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82 articles for “Response Surface Method”
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Research ArticleOpen accessIn the keywordsNattokinase Activity Guided Natto Fermentation Process OptimizationXiaojie Ren, Chao Huang, Xin Shan et al.The natto kinase in natto has obvious thrombolytic effect, has the advantages of low cost, small side effects, long half-life and can be taken orally, so it has attracted much attention. At present, the research on natto kinase in our country mainly focuses on the selection of natto fermentation strains, the optimization of gene expression conditions and the exploration of … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 4 · 20 Dec 2021 · 7,151 accessesView PDFCite
Research ArticleOpen accessIn the keywordsPhosphorylation, Characterization, and Antioxidant Activity of Polysaccharides from Flammulina Velutipes ScrapsYingyun Peng, Xue Bai, Hanwen Xu et al.In this study, polysaccharides from Flammulina velutipes Scraps(FVSP) were extracted. The preparation conditions of the Phosphorylated derivativeof FVSP (Ph-FVSP) were optimized based on single experiments and responsesurface analysis. Characterization and antioxidant properties of FVSP andPh-FVSP were investigated. The optimum phosphorylation modification process ofFVSP obtained was as follows: The mass ratio of STPP/STMP was 1:2, the reaction temperature was 70℃, the … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 3 · 16 Aug 2022 · 6,007 accessesView PDFCite
Research ArticleOpen accessIn the keywordsAssessment of Surface Treatment on Fatigue Life of Cylinder Block for Linear Engine using Frequency Response ApproachM. M. Rahman, A. K. Ariffin, S. Abdullah et al.Objectives: This study was focused on the finite element techniques to investigate the effect of surface treatment on the fatigue life of the vibrating cylinder block for new two-stroke free piston engine using random loading conditions. Motivation: An understanding of the effects related to the random loading is necessary to improve the ability of designers to accurately predict the fatigue … …American Journal of Applied Sciences, Vol. 6, Issue 4 · 30 Apr 2009 · 8,139 accessesView PDFCite
Research ArticleOpen accessIn the abstractDevelopment of Multifunctional Health Food Based on Smilax Glabra ExtractLiuzhou ZhangWith the increasing demand for health management, the development of functional foods based on natural plant extracts has received widespread attention. Due to its medicinal and edible properties, the Smilax glabra extract has become an ideal raw material for multifunctional health foods. Therefore, a new type of chewable tablet based on Smilax glabra extract is developed by optimizing the preparation … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 28 Feb 2026 · 1,744 accessesView PDFCite
Research ArticleOpen accessIn the abstractPolygonatum sibiricum Red. With Steaming Yellow Rice Wine: Processing Technology, the Content of 5 Hydroxymethylfurfura and Safety AssessmentShiyu Ji, Shuo Li et al.To investigate the content and safety evaluation of 5 Hydroxymethylfurfural (5-HMF) in the processing of Polygonatum sibiricum Red, the steaming technology was optimized by response surface method combined with analytic hierarchy process of multiple indexes. The content of 5-HMF was quantitatively determined by HPLC. Safety assessment was conducted using a zebrafish model. The optimized conditions were a steaming time of … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 2 · 20 Nov 2025 · 2,587 accessesView PDFCite
Research ArticleOpen accessIn the abstractPreparation of D-Phenyllactic Acid-Chitosan Biodegradable Composite Coating and Its Preservation Effect on Shine-Muscat GrapeDongxing Zhu, Guanglun Xiong, Wenli Tang et al.Considering the pollution of plastic packaging and the harm of traditional food containing sulphur to the environment and human health, the development of green and edible coating materials with biodegradable power has become the focus of attention in recent years. In this study, based on a single factor test, D-Phenyl Lactic Acid-Chitosan Biodegradable Composite Coating (PACBC) was prepared by optimizing … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 1 · 23 Mar 2025 · 5,057 accessesView PDFCite
Research ArticleOpen accessIn the abstractOptimization of Purification Technology and Antioxidant Activity of Total Flavonoids from Sea Buckthorn LeavesJiale Shan, Yang Liu, Pu Zhao et al.China is rich in sea buckthorn (Hippophae rhamnoides L.)resources and a large amount of sea buckthorn fruit is used to extract oil andjuice every year. However, Sea Buckthorn Leaves (SBL), which are full offlavonoids, are discarded as waste. To make full use of resources and turn waste into valuables, theoptimal purification process of flavonoids from SBL was studied and theantioxidant … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 3 · 27 Aug 2022 · 6,073 accessesView PDFCite
Research ArticleOpen accessIn the abstractProducing Functional Fatty Acid DHA from Corn Steep Liquor by Aurantiochytrium SW1Xiaojie Ren, Qi Yan, Baoyue Liu et al.Thraustochytrium has a relatively high lipid content in the cell and its lipid content can account up to 70% of the dry cell weight. It is an important raw material for the third-generation biodiesel production and the production of functional fatty acid Docosahexaenoic Acid (DHA). However, the high cost of traditional fermentation medium has hindered the industrial production of lipid. … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 4 · 20 Nov 2021 · 6,323 accessesView PDFCite
Research ArticleOpen accessIn the abstractOptimization of α-Glucosidase Inhibitors Recovery from Rainbow Trout Hydrolysate Using GA-BP Neural NetworkYingke Chu, Yanling Dong, Qingfeng Rong et al.To enhance the value of by-products from rainbow trout processing, the inhibition rate of α-glucosidase (AGIR) is used as indicators. Optimization of rainbow trout hydrolysate extraction by comparing Response Surface Methodology (RSM) and BP Neural Network (BPNN) models. The RSM results: the AGIR is 55.02%. BPNN models predicted the optimal extraction conditions: 51℃ for temperature,1:2.3 for solid-liquid ratio, 4.15 h … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 3 · 28 Jan 2026 · 1,734 accessesView PDFCite
Research ArticleOpen accessIn the abstractOptimization of Chelating Process of Polysaccharides of Lyophyllum decastes with Zinc and Its Antioxidant ActivityBing Xu, Yi Dai, Jing Hong, Yiyong ChenIn this study, polysaccharides of Lyophyllum decastes (LDS) were used as raw material. The chelating rate was set as the index, the effect of chelating time, mass ratio and initial mass concentration on chelating rate was investigated. Response surface method was used to optimize the preparation technology of LDS and Zinc (Ⅱ) chelate (LDS-Zn) based on single factor experiments. LDS-Zn … …Current Research in Bioinformatics, Vol. 9, Issue 1 · 26 Aug 2020 · 11,761 accessesView PDFCite