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181 articles for “Receptor”
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Research ArticleOpen accessEvery word in the titleElectromagnetic Field and Γ Aminobutyric Acid a Receptors Interaction in the Fear ResponseM. Taherianfard, A. Bahaodini, M. Fazeli et al.Freezing behavior is a fearful reaction to specific stimuli, most commonly observed by animals. One of the neurotransmission system most consistently linked with fear response is the GABAergic system, in which GABA through GABAA receptor can influence fear response. The aim of the present investigation was to examine the effect of IP injection of muscimol (GABAA agonist) and bicuculline (GABAA … …Current Research in Psychology, Vol. 4, Issue 1 · 4 Sep 2013 · 7,520 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleSpatial Distribution of Fibroblast Growth Factor Receptor 2 in Normal and Lesioned Central Nervous System of Pleurodeles waltliiMarie Moftah, Marc Landry, Frederic Nagy, Jean-Marie CabelguenFibroblast Growth Factors (FGFs) have been implicated in numerous cellular processes including proliferation, migration, differentiation and neuronal survival. One of these growth factors, Fibroblast Growth Factor 2 (FGF2), is apparently implicated in the ability of the adult salamander (Pleurodeles waltlii) to recover locomotion following complete transection of the spinal cord. In a previous study, we reported up regulation of FGF2 … …Neuroscience International, Vol. 3, Issue 2 · 4 Sep 2012 · 7,151 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleBlockade of Group I Metabotropic Glutamate Receptors (mGluRs) Activation Inhibits Nociception Following Descending Colon Distension in SheepBogdan F. Kania, Danuta Wrońska, Mikołaj A. GralakExpression of mGluRs of groups I and II was found in structures of CNS closely related with nociception: spinal cord superficial fields, responsible for pain filling or modulation of neurotransmission in the peripheral receptors. The present study examined contribution of mGluRs to the development and maintenance of changes in behavioral and clinical symptoms caused by visceral pain. Experiments were carried … …American Journal of Animal and Veterinary Sciences, Vol. 9, Issue 4 · 24 Dec 2014 · 7,431 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleγAminobutyrate B Receptors in Central Amygdaloid and Medial Amygdaloid Nuclei of Amygdala Modulate Aggression in Male RatsMahnaz Taherianfard, Zahed Abdolahi, Hamid Rajaian et al.One neurochemical system most consistently linked with aggression is the GABAergic system. The aim of the present investigation was to examine the effect of injection of baclofen (GABAB agonist) and CGP35348 (GABAB antagonist) in the Central Amygdaloid (CA) and Medial Amygdaloid (MA) nuclei of the amygdala on offensive aggression behavior in the animal model. Sixty six adult male rats weighing … …Neuroscience International, Vol. 3, Issue 1 · 3 Sep 2012 · 7,261 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleMolecular Detection of Follicle Stimulating Hormone Receptor Polymorphisms and Luteinizing Hormone Gene Variations in Primary and Secondary Iraqi Infertile WomenNoor Basim Naser, Dr. Ezeddin Atia Albayyar, Dr. Susan Abed ZaidanThe current study aimed to determine the role of hormonal disturbances in infertility, moreover assessing variations at the molecular level that could affect this disease. The study examined 90 blood samples, 30 patients with primary infertility, 30 patients with secondary infertility and 30 healthy women as control. FSH and LH were measured using Electrochemiluminescence assay. DNA was isolated for molecular … …OnLine Journal of Biological Sciences, Vol. 18, Issue 4 · 15 Nov 2018 · 7,558 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleSoluble Tumor Necrosis Factor Receptor Type I and Dranulysin as Immunological Markers in Congestive Heart FailureSimone de Lima e Silva Deo, Maria Do Carmo Valente De Crasto, Alda Maria Da-Cruz et al.Previous studies have shown that circulating levels of cytokines are increased in patients with congestive heart failure (CHF), resulting in myocardial depression. In this work, we have determined serum levels of TNF-α and IFN-γ by ELISA, detected sTNFR-I by dot ELISA, as well as TNFα, IL-6, IL-10 and granulysin mRNA in unstimulated peripheral blood mononuclear cells (PBMC) by RT-PCR in … …American Journal of Immunology, Vol. 1, Issue 3 · 30 Sep 2005 · 6,776 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleExpression of Toll-like Receptors (TLRs) and Nucleotide-binding Oligomerization Domain (NODs) in murine peritoneal macrophages on in vitro treatment with Thymosin α 1Shikha Tarang, Ajit SodhiThymosin α 1 (Tα1) treatment of murine peritoneal macrophages in vitro induces the expression of TLRs and Nod2 proteins. Enhanced expressions of TLR2, -4, -5, -6, -7, -8, -9 and Nod2 were observed by RT-PCR and western blotting. Expression of downstream signaling molecules - MyD88, IRAK1, TRAF6, IRF3 were also up regulated on treatment with Tα1. It was also observed … …American Journal of Immunology, Vol. 3, Issue 1 · 30 Jun 2007 · 7,154 accessesView PDFCite
Research ArticleOpen accessIn the keywordsDetermination of Diplotypes Associated with Meat Productivity in Cattle Breeds Common in the Territory of the Republic of KazakhstanAskar Mirzahmetovich Nametov, Indira Saltanovna Beishova, Alena Valentinovna Belaya et al.Technologies for genetic labeling of economically useful traits using polymorphic variants of genes that control the rate of growth and development of animals make it possible to assess the genetic potential of an animal immediately after birth, which significantly reduces time and financial costs. This study aimed to identify paired combinations of the genes growth hormone, growth hormone receptor, and … …OnLine Journal of Biological Sciences, Vol. 22, Issue 3 · 17 Aug 2022 · 6,190 accessesView PDFCite
Research ArticleOpen accessIn the keywordsMarking of Genetic Resistance to Chlamydia, Brucellosis and Mastitis in Holstein Cows by Using Polymorphic Variants of LTF, MBL1 and TLR9 GenesIndira Beishova, Birzhan Nurgaliyev, Alena Belaya et al.The purpose of the research is to study the association of polymorphic variants of the Toll-Like Receptor 9 (TLR9), Mannose-Binding Lectin 1 (MBL1), and Lactoferrin (LTF) genes with the incidence of chlamydia, brucellosis and mastitis in Holstein cows. Samples of Holstein cows with established diagnoses of chlamydia, brucellosis, and mastitis were characterized by the nature of the correspondence of the … …American Journal of Animal and Veterinary Sciences, Vol. 18, Issue 2 · 6 May 2023 · 6,161 accessesView PDFCite
HypothesisOpen accessIn the keywordsCJ-023,423 (Grapiprant) a Potential Novel Active Compound with Antihyperalgetic Properties for Veterinary PatientsMario GiorgiCompanion animals are now living longer and so are more commonly manifesting age- and pain-related disease. Nonsteroidal anti-inflammatory drugs are the most used drug in osteoarthritis and inflammatory pain of various aetiologies. Despite their safety profiles have been amended from the COX-non selective to the COX-2 selective inhibitor class, some adverse effects are still of concern especially in long term … …American Journal of Animal and Veterinary Sciences, Vol. 10, Issue 2 · 14 May 2015 · 8,877 accessesView PDFCite