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284 results for “Inhibitor”
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Research ArticleOpen accessIn the keywordsAnticonvulsant Effect of Pitavastatin in Mice Induced by PentylenetetrazoleKhayatnouri MirhadiProblem statement: The 3-Hydroxy-3-Methylglutaryl-CoA (HMG-CoA) reductase inhibitors (statins) have been unequivocally shown to reduce cardiovascular morbidity and mortality by their lipid-lowering actions. It has been suggested that statins appear to have therapeutic benefits in diseases that are unrelated to elevated serum cholesterol levels. The aim of this study was to evaluation the effect of intraperitoneally injection of different doses of … …American Journal of Animal and Veterinary Sciences, Vol. 6, Issue 4 · 11 Jan 2012 · 7,511 accessesView PDFCite
Research ArticleOpen accessIn the keywordsCharacteristics of Antagonistic Activity of Two Trichoderma Species New to Kazakhstan Against Soil PathogensYelena Rakhimova, Assem Assylbek, Lyazzat Kyzmetova et al.The high efficiency of representatives of the Trichoderma genus in suppressing a wide range of plant pathogens contributes to the conduct of large-scale research on the search for local strains. The purpose of this study is to characterize the antagonistic activity of two Trichoderma species new to Kazakhstan (T. pararogersonii and T. rossicum) isolated from the rhizosphere of Picea schrenkiana … …OnLine Journal of Biological Sciences, Vol. 23, Issue 4 · 17 Oct 2023 · 4,461 accessesView PDFCite
Research ArticleOpen accessIn the keywordsAqueous Extracts of Bay Leaf (Laurus nobilis) and Rosemary (Rosmarinus officinalis) Inhibit Iron-Induced Lipid Peroxidation and Key-Enzymes Implicated in Alzheimer’s Disease in Rat Brain-in VitroAyodeji O. Falade, Goodness I. Omolaiye, Kayode E. Adewole et al.Neurological disorders remain a global health challenge, with Alzheimer’s Disease (AD) as the most famous cause of dementia in old people. Nevertheless, culinary spices and herbs have shown promising potentials in the management of neurological diseases. This study aimed at investigating the neuroprotective property of aqueous extracts of bay leaf (Laurus nobilis) and rosemary (Rosmarinus officinalis) by assessing the antioxidant … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 1 · 25 Jan 2022 · 7,961 accessesView PDFCite
Research ArticleOpen accessIn the keywordsAssessment of Therapeutic Effects of Platelet-Rich Plasma in Knee Osteoarthritis: Possible Role of Inflammatory CytokinesMohammed H. Hassan, Sawsan Abuhamdah et al.Osteoarthritis (OA) is a multifactorial disease that commonly affects the knee. Tumor Necrosis Factor-α (TNF-α) regulates inflammation during OA. Macrophage Migration Inhibitory Factor (MIF) may be involved in the pathophysiology of arthritis. Platelet-Rich Plasma (PRP) may reduce pain associated with OA. The present study assessed the possible therapeutic effects of PRP in patients with OA of the knee with varying … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 2 · 15 Jun 2021 · 6,991 accessesView PDFCite
Research ArticleOpen accessIn the keywordsFrequency of Carbapenem Resistance among Gram Negative Pathogens in a Tertiary Care Hospital in Southern PakistanWaseela Ashraf, Altaf AhmedCarbapenems are considered the treatment of choice for treating the multi-drug resistance Gram negative bacteria. But resistance to these antibiotics has increased worldwide thus limiting therapeutic options for clinicians. To investigate the frequency and Minimum Inhibitory Concentrations (MICs) of carbapenem resistance in Gram negative organisms at a tertiary care hospital in Southern Pakistan. Seven Hundred and ninety-three carbapenem resistant isolates … …American Journal of Infectious Diseases, Vol. 11, Issue 4 · 29 Oct 2015 · 7,582 accessesView PDFCite
Review ArticleOpen accessIn the keywordsVascular Endothelial Growth Factor: An Overview Across Multiple Disease ConditionsMiriam CanaveseVascular Endothelial Growth Factor (VEGF) is the major player in the regulation of physiological angiogenesis as well as it has also been implicated in pathological angiogenesis, associated with cancers and other conditions, among which psoriasis, autoimmune diseases and visual loss in macular degeneration. Interestingly, three regulatory Single Nucleotide Polymorphisms (rSNPs) in the promoter region of VEGF-A gene have been significantly … …American Journal of Pharmacology and Toxicology, Vol. 10, Issue 1 · 6 May 2015 · 7,102 accessesView PDFCite
Research ArticleOpen accessIn the keywordsEVALUATION OF ANTIMICROBIAL ACTIVITY IN OLIVE (OLEA EUROPAEA) LEAF EXTRACTMukadderat Gökmen, Recep Kara, Levent Akkaya et al.In this study the antimicrobial activity of Olive Leaf Extracts (OLE) was screened against five gram-positive and five gram-negative bacteria. The antimicrobial activity was evaluated using disc diffusion and microdilution methods. The diameters of inhibition zones of the olive leaf extract were observed 13.33±2.08 mm against S. typhimurium and 21.67±1.53 mm against B. cereus. There was a similarity between the … …Current Research in Microbiology, Vol. 5, Issue 2 · 15 Jan 2015 · 15,218 accessesView PDFCite
Research ArticleOpen accessIn the keywordsPrevalence and Inhibition of Microbial Load on Chicken Eggs with Special References to Egg Quality and HatchabilityJehan Ismail Ibrahim, H. Dalia Mansour, Hosny Abdellatief AbdelrahmanA total of 304 random chicken egg samples obtained from layers of Balady and Battery systems. 144 of chicken Balady and Battery eggs (72 of each sample were divided into 18 batches) were used for bacteriological evaluation. Enterobactriacae (94.4, 33.3 and 27.7%), Salmonella (77, 29 and 22%), E.coli (44, 0 and 22%) and Staphylococcus aureus (100, 97 and 98%) were … …American Journal of Animal and Veterinary Sciences, Vol. 9, Issue 4 · 26 Dec 2014 · 7,851 accessesView PDFCite
Research ArticleOpen accessIn the keywordsCOMPARATIVE STUDY OF ANTIBACTERIAL ACTIVITY OF PLANT EXTRACTS FROM SEVERAL REGIONS OF ASIAAwatif Al-Judaibi, Ashwag Al-Zahrani, Khadijah A. Altammar et al.This study was designed to investigate the antibacterial activities of alcohol extracts of Phoenix dactylifera (date palm ’type Ajwa’), Nigella sativa (black cumin), Elettaria cardamomum (cardamom), Tinospora crispa (Akar patawali) and Panax ginseng (ginseng). The plant extracts were prepared with methanol and assayed for antibacterial activity against Methicillin-Resistant Staphylococcus Aureus (MRSA) and S. aureus. Extracts of N. sativa, E. cardamomum … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 2 · 2 Apr 2014 · 7,574 accessesView PDFCite
Research ArticleOpen accessIn the keywordsAssessment of Neuropharmacological Activities of Terminalia Chebula in RatsWathita Phachonpai, Jintanaporn Wattanathorn, Terdthai Tong-un et al.Problem statement: Oxidative stress has been implicated in the pathophysiology of many neurodegenerative diseases such as Alzheimer’s Disease (AD). In traditional practices of Ayurvedic medicine, numerous herbs have been used to treat cognitive disorders. Terminalia Chebula (Combretaceae; TC), is a well-known Ayurvedic herbal remedy which possesses an antioxidant activity. The scientific literature strongly supports its in vitro exerted acetylcholinesterase inhibitory … …American Journal of Pharmacology and Toxicology, Vol. 7, Issue 2 · 11 Jun 2012 · 8,297 accessesView PDFCite