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60 articles for “Hepatitis”
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Research ArticleOpen accessIn the abstractDetection of HCV Components and Pathological Reactions in Apoptotic Hepatocytes from Chronically HCV-infected PatientsViviana Falcón, Nelson Acosta-Rivero, Mineko Shibayama et al.Analysis of Hepatitis C Virus (HCV)-infected hepatocytes at the cellular level may contribute to elucidate the mechanisms of HCV pathogenesis. In this work, the presence of HCV components and pathological reactions in apoptotic hepatocytes from chronic HCV-infected patients were studied by electron microscopy and confocal microscopy. Eight samples of liver biopsies from patients with chronic hepatitis C were studied by … …American Journal of Infectious Diseases, Vol. 1, Issue 1 · 31 Mar 2005 · 6,907 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Kit for Multiplexed Detection of Antibodies to Agents of Hemotransmissible InfectionsAlexander Poltavchenko, Anna Ersh, Pavel Filatov et al.The paper presents the results of laboratory trials of method using complex initial testing of antibodies to six agents of hemotransmissible infections: HIV, hepatitis B and C viruses, cytomegalovirus, Treponema pallidum and Toxoplasma gondii. The method is based on multiplexed dot immunoassay using plane protein arrays (immunochips) with the use of colloidal gold conjugates and silver development. We describe composition … …OnLine Journal of Biological Sciences, Vol. 16, Issue 3 · 6 Sep 2016 · 7,165 accessesView PDFCite
Research ArticleOpen accessIn the abstractReverse Pharmacology-A Paradigm Shift for Drug Discovery and DevelopmentAshok D.B. VaidyaThe current scenario of drug discovery and development is facing a model perturbation, despite significant advances in genomics, proteomics, metabolomics, combinatorial chemistry and high through put assays. There is an urgent need of a paradigm shift in approaches to drug discovery. Natural products of Ayurveda offer a vast potential for novel phytomolecules with clinical activity. In India, Ayurveda is availed … …Current Research in Drug Discovery, Vol. 1, Issue 2 · 26 Jan 2015 · 15,398 accessesView PDFCite
Research ArticleOpen accessIn the abstractHEPATOTOXIC EFFECT OF ITRACONAZOLE IN EXPERIMENTAL RATSMohammed El-Hassan Abdelmaged KemeirItraconazole is a widely used antifungal drug. In situations such as managing patients with gastrointestinal basidiobolomycosis, third of which cases world-wide occur in the southwestern region of Saudi Arabia, prolonged treatment with this drug is required. Thus, this is study was designed to investigate the hepatotoxicity of long term administration of itraconazolein in Wistar rats. Two groups of rats were … …American Journal of Animal and Veterinary Sciences, Vol. 9, Issue 1 · 30 Jan 2014 · 9,042 accessesView PDFCite
Research ArticleOpen accessIn the abstractDiagnosis Value of Bone Marrow Study in the Disseminated Infection by Mycobacteria: Case ReportAna Guadalupe Mauricio Campos, Francisco De Paz Andres, Paola Beneit et al.The bone marrow examination is useful in order to get an etiologic diagnosis of cytopenias and for the detection of opportunistic diseases in immunocompromised patients. Nevertheless, its role in the diagnosis of invasive infections caused by mycobacterium has not been clearly defined. We describe the case of a 42-year-old woman who was admitted to study anemia, diarrhea and constitutional syndrome … …American Journal of Infectious Diseases, Vol. 8, Issue 3 · 9 Oct 2012 · 7,829 accessesView PDFCite
Research ArticleOpen accessIn the abstractPrevalence Study of Etiologies of Developmental Defects of Enamel of First Permanent Molar among Six to Seven Years Old ChildrenF. Farrokh Gisoo, A. MohseniProblem statement: The final product of amelogensis which generates in three subsequent phases is dental enamel. These Phases are divided into: excretory, calcification and maturation stage of enamel. While these specific complex events, are affected by specific agents, the act of amelogenic cells will be disturbed and hence the results of this process is improper and imperfect enamel production which … …Current Research in Dentistry, Vol. 1, Issue 2 · 16 Jul 2011 · 7,620 accessesView PDFCite
Research ArticleOpen accessIn the abstractMedical Consequences of Drug Abuse and Co-occurring Infections: A Brief ReviewJag H. KhalsaToday substance abuse remains one of the major problems in the world with millions of people abusing legal and illegal drugs. In addition, almost one-third of the world population of 6.7 billion people may also be infected with one or more infections. Both drugs of abuse and infections are associated with enormous burden of social, economic and health consequences. This … …American Journal of Infectious Diseases, Vol. 3, Issue 4 · 31 Dec 2007 · 6,732 accessesView PDFCite
Research ArticleOpen accessIn the abstractHormonal and Metabolic Disorders of Human Immunodeficiency Virus Infection and Substance AbuseJag H. Khalsa, Frank Vocci, Adrian DobsThere are an estimated 200 million users of an illicit drug in the world today. In addition, an estimated 40 million people are infected with the human immunodeficiency virus (HIV) and an estimated 180 million people are infected with the hepatitis C virus (HCV). Both the use of an illicit drug and the co-occurrence of infections are associated with a … …American Journal of Infectious Diseases, Vol. 2, Issue 3 · 30 Sep 2006 · 6,715 accessesView PDFCite
Research ArticleOpen accessIn the abstractNeuropsychological Dysfunction among HIV Infected Drug AbusersRamani S. Durvasula, Charles H. HinkinHuman immunodeficiency virus (HIV) has been documented to cause direct and indirect central nervous system dysfunction that can be observed as a progressive decline in neuropsychological functioning in a large proportion of persons with HIV and AIDS. Neuropsychological decline in individuals with HIV is characterized by cognitive and motor slowing, attentional deficits, executive dysfunction and memory impairment (characterized by intact … …American Journal of Infectious Diseases, Vol. 2, Issue 2 · 30 Jun 2006 · 7,155 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Changing Pathology of NeuroAIDS Associated with Drug Abuse in the Era of HAARTE Bell Jeanne, C. Anthony Iain, Simmonds PeterCompliance with highly active antiretroviral therapy (HAART) arrests HIV induced immune collapse and reduces the prevalence of severe central nervous system (CNS) complications, including HIV associated dementia and encephalitis. However minor cognitive disorders remain common and recent autopsy studies have demonstrated the presence of subtle neuropathological abnormalities in HAART treated individuals, including persistent neuroinflammation and enhanced deposition in the brain … …American Journal of Infectious Diseases, Vol. 2, Issue 2 · 30 Jun 2006 · 6,872 accessesView PDFCite