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99 results for “Genetic Factor”
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Research ArticleOpen accessIn the abstractRole of Angiotensin-Converting Enzyme and Vitamin D Receptor Gene Polymorphisms in Cancer Anorexia-Cachexia SyndromeAriele Fabris, Paolo Biagioni, Tiziana Punzi et al.The ubiquitin-proteasome pathway is a crucial connection between aberrant immune system activation, systemic inflammation and Cancer Anorexia-Cachexia Syndrome (CACS), a syndrome that culminates in hyper-activation of the ubiquitin-proteasome pathway. Angiotensin directly up-regulates this pathway, while vitamin D down-regulates it indirectly through the insulin-like growth factor-1 pathway. We investigated the genetic predisposition towards CACS in a cancer population, examining Insertion/Deletion (I/D) … …American Journal of Immunology, Vol. 8, Issue 3 · 2 Aug 2012 · 9,563 accessesView PDFCite
Research ArticleOpen accessIn the abstractMetabolic Fingerprinting of Three Malaysian Ginger (Zingiber officinale Roscoe) Using Gas Chromatography-Mass SpectromertryH.J. Mahdi, R. Andayani, IshakProblem statement: There is a chemical variation among different ginger cultivars detected by previous studies including the volatile and non-volatile oleo-resins. In this study we try to determine whether these variations are related to a genetic factor rather than environmental or intrinsic factors. Approach: A comprehensive metabolic fingerprinting from the leaves of three micro-propagated ginger cultivars Bukit Tinggi, Tanjung Sepat … …American Journal of Applied Sciences, Vol. 7, Issue 1 · 31 Jan 2010 · 7,390 accessesView PDFCite
Research ArticleOpen accessIn the abstractIn vitro Polyploid Induction in Phalaenopsis Aphrodite by PendimethalinPrasetyorini Djarot, Deden Sukmadjaja, Fadya Annisa Chaesarani, SukonoPhalaenopsis aphrodite is a type of orchid with high ornamental and economic value. However, its development for commercial needs in Indonesia is still hindered by the limited availability of varieties. Therefore, enhancing genetic diversity is necessary, one of which is through polyploid induction. Several previous studies reported that pendimethalin effectively duplicates the chromosome numbers of various plant species. The aim … …OnLine Journal of Biological Sciences, Vol. 26, Issue 3 · 22 Aug 2026 · 863 accessesView PDFCite
Review ArticleOpen accessIn the abstractResveratrol for Atherosclerosis: Potential MechanismsAnastasia Vladimirovna Poznyak, Sergey Kozlov, Gulalek A Babayeva et al.Cardiovascular disease is a big problem around the world. At the heart of most serious cardiovascular diseases is such a pathology as atherosclerosis. Atherosclerosis is a complex set of interactions between inflammation, oxidative stress, lipid disorders, and other molecular, genetic, and lifestyle factors. It is this complexity and multicomponent nature of atherogenesis that make the treatment of atherosclerosis a non-trivial … …OnLine Journal of Biological Sciences, Vol. 26, Issue 2 · 11 Aug 2026 · 608 accessesView PDFCite
Research ArticleOpen accessIn the abstractInvestigation of Biochemical and Hormonal Parameters in Male Patients with MigraineDua’a AlHassoon, Omar Atrooz, Husni FarahMigraine is a complex neurological disorder, including hormonal and biochemical imbalances. The physiological changes include neural variations due to genetic, environmental, and lifestyle factors. Therefore, the research aims to investigate total testosterone levels, Acetylcholine (Ach), prolactin, and clinical markers (calcium, magnesium, glucose, and lipid profile) across migraine patients. The research employed a case-control observational design conducted at Al-Ahliyya Amman University, … …OnLine Journal of Biological Sciences, Vol. 26, Issue 2 · 22 Jul 2026 · 823 accessesView PDFCite
Literature ReviewOpen accessIn the abstractSigns of Predisposition to Atherosclerosis in Fetal DevelopmentAnastasia Vladimirovna Poznyak, Igor Alexandrovich Sobenin, Elizaveta M. Pleshko et al.Atherosclerotic Cardiovascular Disease (ASCVD) remains a significant global health concern, contributing to a substantial number of deaths worldwide. The etiology of this condition is multifaceted, influenced by a plethora of genetic and environmental determinants. Notably, certain risk factors and predictive markers associated with ASCVD may already present or emerge during the prenatal or neonatal period. Early recognition of these markers … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 15 Feb 2026 · 1,307 accessesView PDFCite
Research ArticleOpen accessIn the abstractEpigenetic Regulation of Extracellular Matrix Remodeling in Skin Aging: Mechanisms and InteractionsJiguang Yang, Yusong Shi, Xiaoqing YanSkin aging results from complex interactions between genetic factors, environmental stressors, and epigenetic modifications that regulate extracellular matrix (ECM) remodeling. Accumulation of senescent cells impairs tissue regeneration through mechanisms including telomere shortening, reactive oxygen species accumulation, and ultraviolet (UV) radiation exposure. While epigenetic pathways regulate skin homeostasis, regeneration, and senescence, the specific epigenetic changes occurring during UV exposure, chronological aging, … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 15 Feb 2026 · 1,461 accessesView PDFCite
Research ArticleOpen accessIn the abstractMaternal Infection and Neurodevelopmental Disorders in the OffspringHeping ZhouProblem statement: Neurodevelopmental disorders such as schizophrenia and autism have been attributed to both genetic and environmental factors. Whether and how maternal infection as an environmental factor contributes to the development of neurological abnormalities in the offspring remains to be clearly defined. Approach: The literature was reviewed to examine the relationship between maternal infection and neurological disorders such as schizophrenia … …American Journal of Immunology, Vol. 8, Issue 1 · 12 Mar 2012 · 8,151 accessesView PDFCite
Research ArticleOpen accessIn the abstractSpikelets Fertility and Quality of Local Upland Rice (Oryza sativa L.) Seeds Due to High Temperature at Various StagesRisky Ridha, Ellis Nihayati et al.Stress from high temperatures is one of the factors that restrict rice plant growth and development. Rice generative stage sensitivity to high temperatures is well established, but its vegetative stage sensitivity is more uncertain. To identify high-temperature tolerance traits in the vegetative and generative stages, four local upland rice genotypes were tested under high-temperature stress treatment (32-36°C) during the vegetative … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 22 Jul 2024 · 5,018 accessesView PDFCite
Research ArticleOpen accessIn the abstractSpace Distribution of Highland Barley GNS and its Relationship with Environmental Factors in the Qinghai-Tibet PlateauXibo Feng, Gaihua Wang, Jianlin WangIn order to study the space distribution of Grain Number per spike (GNS) and its relationship with the environmental factors in the Qinghai-Tibet Plateau, 83 data samples from different ecological areas were selected for GNS inverstigation. Meanwhile, the seeds of highland barley were harvested and planted in the farm of Xizang Agriculture and Animal Husbandry College; the varieties without genetic … …American Journal of Biochemistry and Biotechnology, Vol. 14, Issue 2 · 26 Apr 2018 · 10,838 accessesView PDFCite