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72 results for “Gastrointestinal”

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Research ArticleOpen accessIn the abstractA Phenolic Ester of O-Desmethylvenlafaxine (ODV) Improves Uptake of ODV into the BrainYang Zhang, Zhichao Yang, Sen Zhao, Hongli ZhouIn this study, the in vitro stabilities of a promising O-Desmethylvenlafaxine (ODV) phenolic ester prodrug O-19 in aqueous solution, rat whole blood and rat liver microsomes were investigated. In addition, the in vivo drug metabolites were determined using LC-TOFMS-IDA-MS/MS. O-19 exhibits high stabilities at any pH encountered in the gastrointestinal tract, its half live (t1/2) spans the range 5.0±0.18 d … …American Journal of Biochemistry and Biotechnology, Vol. 12, Issue 4 · 11 Dec 2016 · 7,162 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of a Mushroom (Coriolus versicolor) Based Probiotic on Goat HealthKingsley Ekwemalor, Emmanuel Asiamah, Sarah Adjei-Fremah, Mulumebet WorkuMaintenance of an adequate immune response is essential to goat health. CorPet biomass is a mushroom (Coriolus versicolor) based probiotic used as an immune-stimulant in man, horses and small animals. Fifteen BoerXSpanish goats were used in a crossover design to evaluate the effect of a commercial mushroom based probiotic across two periods on resilience of goats to gastrointestinal parasites in … …American Journal of Animal and Veterinary Sciences, Vol. 11, Issue 3 · 4 Oct 2016 · 7,925 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnatomical Changes of Akar Putra Chicken Digestive System after Partial Ablation of Uropygial GlandHasan Saad Jawad, Lokman Hakim bin Idris, Md Zuki bin Bakar, Azhar bin KassimThe current study proposes anatomical changes in the digestive system of 120 Akar Putra chicken after surgical removing of auropygial gland. The experiment comprised of five treatments (24 chicken/treatment), with 3 replicates (8 chicken/replicate). The experimental treatments consist of a control treatment T1; partial ablation of the uropygial gland were applied on T2, T3, T4 and T5 treatments at 3, … …American Journal of Animal and Veterinary Sciences, Vol. 10, Issue 4 · 28 Oct 2015 · 8,289 accessesView PDFCite
Case ReportOpen accessIn the abstractAbrus Precatorius Induced Hemorrhagic ColitisRajeshkumar Ganesan, Rajalakshmi EttiyanAbrus Precatorius commonly known as Rosary bead or Kundumani (Arena, 1986) is an irritant poison affecting almost all major systems of the body with more damage to the gastrointestinal system. The mortality rate is 10 to 15% for a lethal dose of just 1-2 crushed seeds. Following is the case report of hemorrhagic colitis due to the ingestion of a … …American Journal of Pharmacology and Toxicology, Vol. 10, Issue 2 · 13 Sep 2015 · 7,845 accessesView PDFCite
Research ArticleOpen accessIn the abstractMELATONIN PROTECTS THE INTEGRITY OF GASTRIC STRUCTURE FROM A STERILE TISSUE INJURY AND AUGMENTS BOTH MONONUCLEAR AND POLYMORPHONUCLEAR PERIPHERAL BLOOD CELLS INDUCED BY THE INJURY IN WISTAR ALBINO RATSBahjat Al-AniPeptic ulcer is a common upper gastrointestinal disease that remains a major public health problem. Gastric ulceration caused by Nonsteroidal Anti-Inflammatory Drugs (NSAID), stress and alcohol are the common causes of gastric ulcer formation in humans following helicobacter pylori bacterial infection of the stomach. The neurohormone, melatonin was reported to protect against NSAID- and stress-induced gastric lesions. We sought to … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 2 · 17 Mar 2014 · 7,230 accessesView PDFCite
Research ArticleOpen accessIn the abstractHEPATOTOXIC EFFECT OF ITRACONAZOLE IN EXPERIMENTAL RATSMohammed El-Hassan Abdelmaged KemeirItraconazole is a widely used antifungal drug. In situations such as managing patients with gastrointestinal basidiobolomycosis, third of which cases world-wide occur in the southwestern region of Saudi Arabia, prolonged treatment with this drug is required. Thus, this is study was designed to investigate the hepatotoxicity of long term administration of itraconazolein in Wistar rats. Two groups of rats were … …American Journal of Animal and Veterinary Sciences, Vol. 9, Issue 1 · 30 Jan 2014 · 9,049 accessesView PDFCite
Research ArticleOpen accessIn the abstractPHENOTYPING, VIRULENCE CHARACTERISTICS OF AEROMONAS SPECIES AND THE EFFECTS OF ESSENTIAL PLANT OILS AS ANTIMICROBIAL AGENTS AGAINST PATHOGENIC ISOLATES FROM DIFFERENT SOURCESAhmed M.A. Mansour, Hoda M. Zaki, Nibal A. Hassan, Nihad A.M. El-NasharAeromonas species are increasingly recognized as enteric pathogens. Faecal samples from 20 cow, 45 sheep; 60 goat and 60 camels were examined for the presence of Aeromonas species, which was also sought in the available drinking water (55 well water and 52 drinking chlorinated tap water were also examined). Aeromonas species was isolated more frequently from goats (21.7%) than from … …American Journal of Infectious Diseases, Vol. 10, Issue 1 · 18 Jan 2014 · 8,024 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Chromium(VI) on Serum Iron and Removal of its Toxicity by Combining Deferasirox and Deferiprone Chelators in RatsS. Jamil A. Fatemi, Marzieh Iranmanesh, Faezeh Dahooee BaloochThe present research is aimed to characterize the potential efficiency of two chelators after chromium(VI) administration for 60 days following two doses of 15 and 30 mg kg-1 chromium(VI) per body weight daily to male rats. However, the hypothesis that the two chelators might be more efficient as combined therapy than as single therapy in removing chromium(VI) from bood serum … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 4 · 30 Oct 2013 · 7,156 accessesView PDFCite
Research ArticleOpen accessIn the abstractPrevalence of Abomasal Nematodes in Sheep Slaughtered at Baneh TownGaredaghi Yagoob, Hashemzadefarhang Hossein, Fattahi AssoLivestock production covers up to 40% of the gross value of agricultural production globally. Gastrointestinal nematodes of small ruminants are one of the major causes of productivity loss. This study was carried out to determine the correlation between the prevalence, seasonal incidence and geographical distribution of abomasal worm infection of native sheep in Baneh Town of Iran, suitable for animal … …American Journal of Animal and Veterinary Sciences, Vol. 8, Issue 3 · 9 Sep 2013 · 7,339 accessesView PDFCite
Research ArticleOpen accessIn the abstractISOLATION AND CHARACTERIZATION OF HELICOBACTER PYLORI STRAINS FROM GASTRIC BIOPSIES OF ALGERIAN PATIENTSGuetarni Hassina, Bensoltane AhmedThe objective of this study is to isolate and characterize strains Helicobacetr pylori from gastric biopsies by upper gastrointestinal endoscopy. After a rapid urease test, two Helicobacter pylori strains isolated from four patients on blood agar. After extraction of DNA from these strains from homogenates of gastric biopsies, quantification by real-time PCR was performed to determine Helicobacter pylori on the … …OnLine Journal of Biological Sciences, Vol. 13, Issue 2 · 19 Apr 2013 · 7,266 accessesView PDFCite