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111 articles for “Blood Cells”
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EditorialOpen accessIn the abstractNeutrophil Extracellular Traps as Therapeutic Targets for Inflammatory DiseaseRory R. KoenenNeutrophilic granulocytes, or neutrophils are the most abundant circulating white blood cell and constitute a first line of defense against pathogens. They are characterized by a large polymorphic lobular nucleus and the presence of many secretory granules in their cytoplasm. Neutrophils are essential for a functional host defense, as is evidenced by the occurrence of severe infections in individuals with … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 4 · 25 Feb 2015 · 8,740 accessesView PDFCite
Research ArticleOpen accessIn the abstractHaematological Status for Selected Pig BreedsJanka Kotosová, Janka Poráčová, Ladislav Vaško et al.Changes which are constantly brought by the transformation of our agriculture, as well as the effort to be involved in the EU market economy and change priorities in various areas of our economy. They can be summarized in the quality, productive health and economy. Blood count does not only change in pigs with age, but it also depends on the … …American Journal of Animal and Veterinary Sciences, Vol. 9, Issue 4 · 23 Dec 2014 · 7,335 accessesView PDFCite
EditorialOpen accessIn the abstractGLUTATHIONE: A POSSIBLE LINK TO AUTOPHAGY IN SYSTEMIC LUPUS ERYTHEMATOSUSDilip Shah, Swapan K. NathIncreased free radical formation and altered redox state are of fundamental importance in the pathogenesis of autoimmune diseases including Systemic Lupus Erythematos (SLE). Free radicals are mainly derived from oxygen (Reactive Oxygen Species/ROS) and nitrogen (Reactive Nitrogen Species/RNS) at mitochondria, cellular membranes and the endoplasmic reticulum membrane as physiological responses to a variety of internal and external stress (Shah et … …American Journal of Immunology, Vol. 10, Issue 3 · 3 Sep 2014 · 12,777 accessesView PDFCite
Research ArticleOpen accessIn the abstractHOMOLOGY MODELING AND MOLECULAR DYNAMICS STUDIES OF EC1 DOMAIN OF VE-CADHERIN TO ELUCIDATE DOCKING INTERACTION WITH CADHERIN-DERIVED PEPTIDEVivitri Dewi Prasasty, Usman Sumo Friend Tambunan, Teruna Jaya SiahaanVE-cadherin is a protein in the cadherin family that is found at the adherens junctions of the microvessel endothelial cells of the Blood-Brain Barrier (BBB). It is recognized as the homotypic cell adhesion molecules and there is limited structural information on how VE-cadherins mediate cell-cell adhesion. It has been shown that the EC1 domain of cadherins is important for the … …OnLine Journal of Biological Sciences, Vol. 14, Issue 2 · 25 Jun 2014 · 7,534 accessesView PDFCite
Research ArticleOpen accessIn the abstractATRA AS A POTENTIAL ANTIMETASTATIC AGENT IN COLORECTAL ADENOCARCINOMARobert Edwards, Kambiz Afrasiabi, Kehui WangThe family of Retinoic acid compounds have long been the subject of intense study and interest as chemo prophylactic agents. This dates back to their therapeutic effect in leukoplakia Where ATRA was shown to lead to the reversal of premalignant lesions and Subsequent reports on their use in metastatic colorectal adenocarcinoma and a vast array of other malignant disorders as … …OnLine Journal of Biological Sciences, Vol. 14, Issue 2 · 26 Mar 2014 · 7,348 accessesView PDFCite
Research ArticleOpen accessIn the abstractCYCLIC CHOLECYSTOKININ ANALOGUES EXHIBIT HIGH BLOOD STABILITY AND BINDING AFFINITY WITH CHOLECYSTOKININ RECEPTOREun-Ha Joh, Jae Cheong Lim, Jin Joo Kim et al.Recently, incidence of Cholecystokinin (CCK) receptor is recognized as a factor that determines the aggressive phenotype of pancreatic cancer. In this study, a novel Cholecystokinin (CCK) analogues; DOTA-Nle-cyclo (Glu-Trp-Met-Asp-Phe-Lys-NH2) (DOTA-cCCK) and DOTA-Nle-cyclo (Glu-Trp-Nle-Asp-Phe-Lys-NH2) (DOTA-[Nle]-cCCK) were synthesized and radiolabeled and the targeting abilities on the CCK receptor were evaluated for new CCK receptor targeting agents searching. Peptides were prepared through a … …OnLine Journal of Biological Sciences, Vol. 14, Issue 1 · 2 Jan 2014 · 7,559 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Comparative Study of the Ovine Haemogram: Cell-Dyn 3500 Versus Manual MethodsLabrini V. Athanasiou, Constantinos G. Giannakopoulos, Zoe S. Polizopoulou et al.Manual hematology techniques traditionally applied in farm animal medicine are time consuming and labor-intensive, especially when large numbers of samples have to be processed. As a result, several automated hematology instruments have been developed for use in these species. An automated hematology analyzer (Abbott Cell-Dyne 3500 system) was used in performing a complete blood cell count and differential counts of … …American Journal of Animal and Veterinary Sciences, Vol. 8, Issue 4 · 23 Oct 2013 · 7,183 accessesView PDFCite
Research ArticleOpen accessIn the abstractInvolvement of Bone Marrow Megakaryocytes in the Formation of the Bone Marrow-Blood Barrier in Transgenic MicePawel Laskowski, Karol Ostrowski, Beata Klim et al.Mature cell release takes place through the hypothetical barrier- the bone marrow-blood barrier. It consists of blood vessels and cells that surround them. Such cells are, among others, megakaryocytes. They are involved in the release of platelets or other cellular components of blood. The amount and the development of megakaryocytes and thus the maturity of barrier depends on many factors. … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 3 · 19 Sep 2013 · 7,185 accessesView PDFCite
Research ArticleOpen accessIn the abstractBiochemical and Hematological Alterations in Mice Inoculated with Outer Membrane Protein, Lipopolysaccharides and Whole Cells of Pasteurella multocida Type B: 2Faez Firdaus Jesse Abdullah, Lawan Adamu, Abdinasir Yusuf Osman et al.Haemorrhagic septicaemia in cattle and buffaloes is an economically important livestock disease in Asia including Malaysia. Therefore, the aim of this study was to investigate the biochemical and hematological alterations in mice model inoculated with outer membrane protein, lipopolysaccharides and whole cells of Pasteurella multocida type B: 2. Two hundred healthy male mice of eight to ten weeks old were … …American Journal of Animal and Veterinary Sciences, Vol. 8, Issue 3 · 17 Sep 2013 · 7,318 accessesView PDFCite
Research ArticleOpen accessIn the abstractDiagnosis Value of Bone Marrow Study in the Disseminated Infection by Mycobacteria: Case ReportAna Guadalupe Mauricio Campos, Francisco De Paz Andres, Paola Beneit et al.The bone marrow examination is useful in order to get an etiologic diagnosis of cytopenias and for the detection of opportunistic diseases in immunocompromised patients. Nevertheless, its role in the diagnosis of invasive infections caused by mycobacterium has not been clearly defined. We describe the case of a 42-year-old woman who was admitted to study anemia, diarrhea and constitutional syndrome … …American Journal of Infectious Diseases, Vol. 8, Issue 3 · 9 Oct 2012 · 7,832 accessesView PDFCite