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132 articles for “toxic effect”
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Research ArticleOpen accessIn the abstractUncommon Toxicologic Profile at Toxic Doses of CPI-613 (an Agent Selectively Alters Tumor Energy Metabolism) in Rats and Minipigs Reflects Novel MechanismClaudia Maturo, King C. Lee, Robert Rodriguez, Robert ShorrProblem statement: CPI-613 is a novel anticancer agent and the toxicological profile has not been assessed. Accordingly, the objective of these studies was to thoroughly evaluate the Toxicokinetic (TK) effects of CPI-613 in rats and to compare the toxicological profile of rats to minipigs to determine if there were differences between the two animal species. Approach: These studies involved assessments … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 4 · 13 Jun 2011 · 9,584 accessesView PDFCite
Research ArticleOpen accessIn the abstractEstimation of Pathogenic Microorganisms during Atmospheric Tempestat North AfricaU. Ali RahomaProblem statement: Dust continued to blow across northern Africa and the Mediterranean Sea on March 3, 2005. Many sources are associated with areas where human impacts are well documented. Approach: Nonetheless, the largest and most active sources are located in truly remote areas where there is little or no human activity. Dust activity is extremely sensitive to many environmental parameters. … …Current Research in Medicine, Vol. 2, Issue 1 · 29 Mar 2011 · 7,402 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of an Insecticide Abamectin on Some Biochemical Characteristics of Tilapia Fish (Oreochromis Niloticus)Mohammed A. Al-KahtaniProblem statement: Presence of pesticide in streams and lakes is largely due to the runoff from agricultural fields. Pesticides are not highly selective but are generally toxic to many macrophytes, non-target organisms such as fish. Fish, generally accumulate contaminants from aquatic environments and have been largely used in food safety studies. Approach: The toxic effect of the insecticide abamectin on … …American Journal of Agricultural and Biological Sciences, Vol. 6, Issue 1 · 15 Dec 2010 · 9,600 accessesView PDFCite
Research ArticleOpen accessIn the abstractDoes Predator Go for Size Selection or Preferential Toxic-Nontoxic Species Under Limited Resource?Joydeep Pal, S. Bhattacharya, J. ChattopadhyayProblem statement: Selectivity is common in predator-prey interaction but the selection mechanism is still unexplored and a debatable issue in modern theoretical and experimental ecology for numerous species across the globe. In present investigation we emphasized the hypothesis that the zooplankton is less inclined to opt the food based on size selectivity criteria than the preferential selectivity for the safe … …OnLine Journal of Biological Sciences, Vol. 10, Issue 1 · 30 Jun 2010 · 7,908 accessesView PDFCite
Research ArticleOpen accessIn the abstractResidential Exposure of Environment Toxic Substance Outcome during Menstrual CycleS. Alagendran, G Archunan, M. P. Jonathan et al.Problem statement: It was intended to diagnose and treat the disorders of female reproductive system where they are exposed to environmentally toxic pesticides and estrogenic compounds like bisphenol A which are the main reason for the infertility problems. Approach: Human saliva contains arrays of proteins that have distinct biological functions. Results: Salivary hormones concentrations of luteinising hormone, follicle stimulating hormone, … …American Journal of Environmental Sciences, Vol. 6, Issue 3 · 30 Jun 2010 · 6,880 accessesView PDFCite
Research ArticleOpen accessIn the abstractSuitability of Using Phragmites australis and Tamarix aphylla as Vegetation Filters in Industrial AreasWafa’a A. Al-TaisanProblem Statement: Many soils of different areas of the world are subjected to heavy metal pollution due to human activities especially the industry. These metals are hazardous to human health and could affect ecosystems. Toxic metal pollution in water and soil is a major environmental problem and most conventional remediation approaches do not provide acceptable solution, hence the studies of … …American Journal of Environmental Sciences, Vol. 5, Issue 6 · 31 Dec 2009 · 8,450 accessesView PDFCite
Research ArticleOpen accessIn the abstractCamel's Milk Protects Against Cadmium Chloride Induced Toxicity in White Albino RatsFahaid Al-Hashem, Mohammad Dallak, Nabil Bashir et al.Problem statement: Cadmium is one of the most dangerous occupational and environmental toxins. It is found in drinking water, atmospheric air and even in food. Cadmium is reported to be very toxic to biological systems. Until now in treating intoxication with this metal, chelating Compounds have been used, burdened with numerous undesirable symptoms. For this reason, many researches are carried … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 3 · 30 Sep 2009 · 9,314 accessesView PDFCite
Research ArticleOpen accessIn the abstractCamel's Milk Protects Against Aluminum Chloride-Induced Normocytic Normocromic Anemia, Lipid Peroxidation and Oxidative Stress in Erythrocytes of White Albino RatsFahaid Al-HashemProblem statement: Aluminum (Al) is an indifferent element from a toxicological point of view. In recent years, however, Al has been implicated in the pathogenesis of several clinical disorders. One of the most frequently described problem in aluminum toxicity is anemia. The present study was carried out to determine the effectiveness of Camel’s milk in alleviating the toxicity of aluminum … …American Journal of Biochemistry and Biotechnology, Vol. 5, Issue 3 · 30 Sep 2009 · 8,026 accessesView PDFCite
Research ArticleOpen accessIn the abstractChemical Contaminants and Toxicity of Ganga River Sediment from Up and Down Stream Area at KanpurK. R. Beg, S. AliThe objective of this study was the sediment quality assessment of Ganga River at Kanpur city where effluents from tannery industries are discharged. Sediment samples from upstream and downstream area were collected and analyzed for trace metals and toxicity bioassay. Among various trace metals examined Cr in downstream sediment was 30-fold higher than in upstream sediment and its concentration was … …American Journal of Environmental Sciences, Vol. 4, Issue 4 · 31 Aug 2008 · 7,608 accessesView PDFCite
Research ArticleOpen accessIn the abstractCocaine: A Catalyst for Human Immunodeficiency Virus-Associated DementiaNavneet K. Dhillon, Milind Gadgil, Andy Rahardja et al.Injection drug use has been recognized as a major risk factor for AIDS from the outset of the epidemic. Cocaine, one of the most widely abused drugs in the United States can both impair the functions of macrophages and CD4+ lymphocytes and also activate HIV-1 expression in these cells. Cocaine is a multifactorial agent that acts globally to impair the … …American Journal of Infectious Diseases, Vol. 4, Issue 2 · 30 Jun 2008 · 7,590 accessesView PDFCite