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167 articles for “replication”
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Research ArticleOpen accessIn the abstractA Fast Access Big Data Approach for Configurable and Scalable Object Storage Enabling Mixed Fault-ToleranceCarlos Roberto Valêncio, André Francisco Morielo Caetano, Angelo Cesar Colombini et al.The progressive growth in the volume of digital data has become a technological challenge of great interest in the field of computer science. That comes because, with the spread of personal computers and networks worldwide, content generation is taking larger proportions and very different formats from what had been usual until then. To analyze and extract relevant knowledge from these … …Journal of Computer Science, Vol. 13, Issue 6 · 1 Jul 2017 · 7,888 accessesView PDFCite
Review ArticleOpen accessIn the abstractThe HCV Replicase InteractomeAntonio Mas, Pilar Clemente-Casares, Eugenio Ramírez, Rosario SabariegosViruses are obligate parasites and can only reproduce within host cells because they lack metabolic pathways to complete their replication cycles. Host factors required in viral replication are mainly those involved in lipid metabolism, cell cycle control and apoptosis, cell-to-cell interactions, immune system regulation, etc. Several inhibitors targeting viral polymerases have been designed. However, the rapid appearance of resistant mutants, … …Current Research in Virology, Vol. 5, Issue 1 · 27 Jul 2016 · 13,210 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Bacterial Chromosomal Sequence and Related IssuesThi Huyen Phan, Duc Luong NguyenThere has been a rapid increasing in the number of bacterial genomes that are completely sequenced recently. However, nucleotide arrangement in bacterial chromosome is still not clear, though it is known that the chromosomal strand is symmetric as a whole but asymmetric locally. The unequal distribution of adenine and thymine as well as cytosine and guanine in the local genomic … …Current Research in Virology, Vol. 2, Issue 1 · 29 Jul 2013 · 13,208 accessesView PDFCite
Research ArticleOpen accessIn the abstractFrequency of P/S(XX)P Duplication and FRFE, Absence of LYP in P6Gag of Indian Human Immunodeficiency Virus-1 Subtype C IsolatesKrutika Wadekar, Sudhanshu Pandey, Preeti Jain et al.Problem statement: The presence of a p6 domain at the C-terminus of the Gag polyprotein is a characteristic feature of HIV-1 and other primate lentiviruses. The p6Gag protein is considered as a major phosphoprotein in mature HIV-1 virions and is involved in the viral assembly and budding process. Sequence variation in the p6gag region in HIV-1 has been associated with … …Current Research in Medicine, Vol. 1, Issue 2 · 31 Oct 2010 · 7,529 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Comparative Study of the Performances of the OLS and some GLS Estimators when Stochastic Regressors are both Collinear and Correlated with Error TermsKayode AyindeThe Classical Linear Regression Model assumes that regressors are non – stochastic, independent and uncorrelated with the error terms. These assumptions are not always tenable especially where regressors are not often assumed fixed in repeated sampling. In this paper, with stochastic regressors, the performances of the Ordinary Least Square (OLS) and some Generalized Least Square (GLS) estimators are investigated and … …Journal of Mathematics and Statistics, Vol. 3, Issue 4 · 31 Dec 2007 · 7,343 accessesView PDFCite
Research ArticleOpen accessIn the abstractRedundancy Schemes for High Availability Computer ClustersChristian K. Bassek, Samuel Pierre, Alejandro QuinteroThe primary goal of computer clusters is to improve computing performances by taking advantage of the parallelism they intrinsically provide. Moreover, their use of redundant hardware components enables them to offer high availability services. In this paper, we present an analytical model for analyzing redundancy schemes and their impact on the cluster’s overall performance. Furthermore, several cluster redundancy techniques are … …Journal of Computer Science, Vol. 2, Issue 1 · 31 Jan 2006 · 7,229 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Role of SLC22A4 Gene Polymorphisms in the Response to Salbutamol in Asthmatic PatientsAlshymaa A. Ahmed, Nora M. Said, Alia A. El Shahaway, Nagwan A. IsmailResponse to Bronchodilators is influenced by many factors including genetics. To evaluate the influence of SLC22A4 gene polymorphisms (rs3792876 and rs2073838) on the response to inhaled salbutamol in asthmatic patients, bronchodilator response was assessed in 180 bronchial asthma patients via measuring changes of the Forced Expiratory Volume in one second (FEV1) after the administration of inhaled salbutamol and genotyping for … …American Journal of Immunology, Vol. 15, Issue 1 · 30 Jun 2019 · 7,470 accessesView PDFCite
Research ArticleOpen accessIn the abstractProduction of Immunologically Active Untagged Recombinant DENV-2 NS1 in Escherichia coliDessy Natalia, Christian Heryakusuma, Fernita Puspasari et al.Dengue is an infectious disease affecting 390 millions people in tropical and subtropical region annually. Dengue virus NS1 protein plays an important role in viral replication in the host cell and it is detected in high level in the infected patient serum. A synthetic gene of untagged DENV-2 NS1 with codons optimization for expression in Escherichia coli has been generated … …American Journal of Biochemistry and Biotechnology, Vol. 14, Issue 3 · 10 Oct 2018 · 10,346 accessesView PDFCite
Research ArticleOpen accessIn the abstractChronic Mental Stress Induces Reversible Reduction of Natural Killer Cells and CD56dim SubpopulationManar M. IsmailGenerally, studying to be a health care provider is a stressful and demanding field and the students have to face many stressors that may affect their general health status including the immune system. This work aimed at studying the effect of prolonged naturalistic life-stress exposure on the percentage of peripheral blood T-lymphocytes and Natural Killer (NK) cells in female laboratory … …American Journal of Immunology, Vol. 13, Issue 3 · 30 Aug 2017 · 7,792 accessesView PDFCite
Review ArticleOpen accessIn the abstractInitiatives to Improve the Quality of Life of HIV Positive Diagnosed Subjects: A Review of Diagnosis, Prognosis and Therapeutics under the Light of Science and EthicsMario Enrique Molina, Jeremías Abou Medelej, Jorgelina Zucchi, Carlos ManasseroThe first cases of AIDS occurred about 1981. There are not fully appropriate therapeutic interventions for treating this medical condition. People who are diagnosed HIV-positive or with AIDS suffer a poor quality of life and receive medication that produces severe adverse reactions. We have analyzed a significant number of papers published in several countries on these topics, and we have … …American Journal of Immunology, Vol. 13, Issue 3 · 3 Aug 2017 · 9,055 accessesView PDFCite