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78 articles for “renal”
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Research ArticleOpen accessIn the abstractEvaluation of Mir 29c-3p and Mir 31-5p Serum Values in Predicting Nephropathy in Type 2 Diabetic PatientsMona S. Habieb, Nesreen Gamal Elhelbawy, Khaled M. Elzorkany et al.Diabetic Nephropathy (DN) is a prime complication of diabetes with various pathological mechanisms. microRNAs (miRNAs) have emerged as an important factor in the pathogenesis of renal disorders. We aimed to analyze serum miR 29c-3p and miR 31-5p in diabetic patients in relation to albuminuria and eGFR. Also, the correlations between these miRNAs and cystatin C were assessed. This study was … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 1 · 17 Feb 2022 · 6,456 accessesView PDFCite
Research ArticleOpen accessIn the abstractPreparation, Identification and Antioxidant Evaluation of Citrullus Colocynthis Root and Fruit Extracts Against Doxorubicin in Male RatsSarah Samir Othman, Gamal M. Hamad, Sabria Abo Zaid Hassan et al.Millions of people are affected by diseases in developing or developed countries. Citrullus colocynthis is a high-antioxidant wildflower, it is healthy to eat and may be used as a source of energy or medication. The goal of this research was to conduct a phytochemical analysis of Citrullus colocynthis fruit extract, which is abundant in Egypt. Different extracts from that plant … …OnLine Journal of Biological Sciences, Vol. 22, Issue 1 · 8 Feb 2022 · 6,250 accessesView PDFCite
Research ArticleOpen accessIn the abstractCharacteristics and Incidence of Candidemia in Hospitalized Coronavirus 2019 (COVID-19) PatientsNaana A Boachie, Jackie P. Johnston, Simi A. Philip et al.Management of Coronavirus 2019 (COVID-19) with high-dose corticosteroids and interleukin-2 inhibitors has potential benefits, but is associated with immunosuppression and risk of secondary infections. This single-center, retrospective, cohort study evaluated the incidence of candidemia and associated risk factors in hospitalized COVID-19 patients. Twenty-three patients developed candidemia and were matched to 77 non-candidemic COVID-19 controls. The primary outcome was incidence of … …American Journal of Infectious Diseases, Vol. 18, Issue 1 · 18 Jan 2022 · 7,604 accessesView PDFCite
Case ReportOpen accessIn the abstractA Case of Leptospira Ards- “Obsession with COVID-19 Leading to Delayed Diagnosis of Common DiseasePrakash Tendulkar, Divanshee Sharma, Mukesh Bairwa, Ravi KantLeptospirosis is a bacterial infection caused by spirochaete. It’s a gram-negative bacterium. It spreads Through animal urine or soil or water contaminated with Animal urine (Rat), when coming into contact with mouth, nose, eyes or breach in the skin. It is more common in farmers and people involved in water sports. In leptospirosis symptoms can range from mild muscle pains, … …American Journal of Infectious Diseases, Vol. 17, Issue 2 · 30 Apr 2021 · 6,784 accessesView PDFCite
Letters to the EditorOpen accessIn the abstractIschemic Stroke in the COVID-19 PatientIvan Lozada-Martinez, Daniela M. Torres-Llinás, Luis R. Moscote-Salazar et al.Currently, there are many questions around the real impact of COVID-19 at an organic level and the resolution of these is one of the main objectives of the scientific societies and public health institutions around the world, to establish the most effective and safe management protocol in the approach of this disease (Qureshi et al., 2020). Systematic reviews and meta-analyses … …Neuroscience International, Vol. 12, Issue 1 · 25 Mar 2021 · 11,648 accessesView PDFCite
Research ArticleOpen accessIn the abstractAssessment of Type 2 Anti-Diabetes on Bound Flavonoids of Barringtonia racemosa (L.) Spreng. Kernel in Glucose-Induced Diabetic RatsMusri Musman, Emelda Audina, Fazlia Inda Rahmayani Ratu et al.A study of type 2 anti-diabetes on bound flavonoids fraction from the kernel of Barringtonia racemosa (L.) Spreng. in glucose-induced diabetic rats was performed. This learning aimed to gather scientific information about the possibility to utilize kernel of B. racemosa as a raw material of antidiabetic drug. The antioxidant property of the bound flavonoids was determined by the DPPH scavenging … …American Journal of Pharmacology and Toxicology, Vol. 12, Issue 3 · 16 Dec 2017 · 8,041 accessesView PDFCite
EditorialOpen accessIn the abstractFocalize the Structure of Myd88 in TLR Signaling Pathway to Modulate Innate Immune Response: New Target for Old DiseasesShuai Xing, Ping ZhouAll diseases have their Achilles’ Heel to target and this is especially true for immunorelated diseases which must be treated by targeting the immune system somewhere and somehow correctly. In the most recent decade, immunologists recognized that the Toll-Like Receptor (TLR) signaling pathway in innate immune system plays a double-edged role in the pathogenesis of many notorious diseases. Although the … …American Journal of Immunology, Vol. 13, Issue 3 · 6 Sep 2017 · 7,865 accessesView PDFCite
Case ReportOpen accessIn the abstractEmphysematous Pyelonephritis with Abscesses Masquerading as an Ordinary Urinary Tract InfectionTasnim F. Imran, Frederick Yick, Ahmed H. Qavi et al.Emphysematous Pyelonephritis (EPN) is a rare, gas-forming infection of the renal parenchyma associated with significant morbidity and mortality. We report the case of a 39 year-old woman with uncontrolled diabetes who presented with abdominal pain, fevers and chills for one month. Physical exam was notable for dry oral mucosa and left costovertebral angle tenderness. Labs showed acute kidney injury and … …American Journal of Infectious Diseases, Vol. 11, Issue 4 · 22 Oct 2015 · 7,751 accessesView PDFCite
EditorialOpen accessIn the abstractImpact of Quantitative Pharmacology on Drug DevelopmentAna Ruiz-Garcia, Kourosh ParivarThesuccess of drug development rests over two well defined pillars, a goodunderstanding of the drug’s clinical pharmacology and the appropriate targetpopulation for whom the clinical use is intended. The label for human prescription drugsrequires a good understanding of the pharmacological effects (pharmacodynamicsor PD) and the mechanism of action of the drug as well as detailed informationof the drug’s Pharmacokinetics (PK): … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 4 · 24 Apr 2015 · 7,164 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Combined Fenofibrate and Nicotinamide on Oxidative Stress and Inflammatory Cytokines Involved in Cisplatin-Induced Nephrotoxicity in RatsOmaima M. Abd Allah, Abeer A.I. Sharaf El-Din, Fouad El DebakeyCisplatin (Cis) is an anticancer drug, which is accompanied with major side effects including nephrotoxicity. The current study was performed to assess the possible prophylactic effects of fenofibrate (FEN), Nicotinamide (NAM) and their combination on oxidative stress and inflammatory cytokines associated with cisplatin-induced renal damage. Rats were randomly divided into seven groups (8 each) as follows; control group; FEN group … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 4 · 9 Jan 2015 · 7,131 accessesView PDFCite