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68 articles for “in vitro Analysis”
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Review ArticleOpen accessIn the abstractEnvironmental Concerns and Toxicogenetic Endpoints of Priority Substances (PSs) and Contaminants of Emerging Concerns (CECs): A Comprehensive ReviewDe-Sheng Pei, Chun-Di Chen, Naima Hamid et al.Priority Substance (PSs) and Contaminant of Emerging Concerns (CECs) exhibited a wide range of environmental and public health concerns worldwide. This review summarized the documented studies related to the current surface water occurrence, spatial distribution, ecological risks and toxicity of selected PSs, such as polycyclic aromatic hydrocarbons (PAHs) and CECs, such as Di(2-Ethylhexyl) Phthalate (DEHP) and Pharmaceuticals and Personal Care … …American Journal of Environmental Sciences, Vol. 14, Issue 3 · 10 Jul 2018 · 8,393 accessesView PDFCite
Research ArticleOpen accessIn the abstractEssential Oil Chemical Composition of Myrtle Growing in Northeastern Algeria and Estimation of its Antibacterial EffectivenessBarhouchi Badra, Aouadi Saoudi, Abdi AkilaThe aim of this study is to determine the antibacterial effectiveness of leaves essential oil extracted from myrtle growing in Algeria. A cluster analysis of soil and water was effectuated for performing chemical and granulometric analyses. The essential oil was isolated from leaves by hydro distillation and analyzed by Gas Chromatography-Mass Spectrometry (GC/MS). The leaves yield reached a peak at … …American Journal of Biochemistry and Biotechnology, Vol. 12, Issue 2 · 5 Apr 2016 · 8,360 accessesView PDFCite
Research ArticleOpen accessIn the abstractTrace Elements Distribution in the Brain of Stressed RatsZerrouk Kamal, Mohamed Najimi, Mohammed Chigr et al.Because of their ability to modulate the Gamma Aminobutyric Acid (GABA) a receptor complex, the principal aim of the current work is to assess two essential heavy metals: Iron (Fe) and zinc (Zn) by atomic absorption in different brain areas of stressed rats. To do so, we investigated the effect of acute immobilization stress (single 1-hour session) on the distribution … …Neuroscience International, Vol. 3, Issue 2 · 14 Sep 2012 · 7,288 accessesView PDFCite
Research ArticleOpen accessIn the abstractDevelopment of Curcumin Based Ophthalmic FormulationD. Anjana, K. Anitha Nair, N. Somashekara et al.Problem statement: Ophthalmic drug delivery system has been a major challenge due to the distinctive and unique anatomy of the eye. The use of phytochemicals for the application in ocular disease has not been investigated much, due to poor pharmacokinetics of phytochemical and hence poor therapeutic efficacy. Approach: Curcumin is one such phytochemical known for its medicinal properties, but its … …American Journal of Infectious Diseases, Vol. 8, Issue 1 · 24 Feb 2012 · 15,409 accessesView PDFCite
Research ArticleOpen accessIn the abstractMicrowave Assisted Regioselective Synthesis and Biological Evaluation of Pyrano[2,3-c]Pyridine Derivatives Utilizing DMAP as a CatalystAsmaa M. FahimRegioselective facile production of pyrano[2,3-c]pyridine through multicomponent reaction of aromatic aldehydes, ethyl cyano acetate or malononitrile and C-H activated compound of 3-hydroxy picolinic acid in the occurrence of smaller amount of DMAP catalyst utilizing microwave apparatus, which is green and simple environmentally with high yield, recyclability catalyst. Totally the products were partitioned for antimicrobiogical action; it was detected that were … …OnLine Journal of Biological Sciences, Vol. 17, Issue 4 · 14 Dec 2017 · 8,022 accessesView PDFCite
Research ArticleOpen accessIn the abstractDetermination of Optimum Values of Descriptors to Set Filters for Synthetic Tri-Pyrrole Derivatives (Prodiginines) Against Multi Drug Resistant Strain of Plasmodium FalciparumVijay H. Masand, Devidas T. Mahajan, Eslam Pourbasheer et al.In the present study, we have carried out extensive non-linear Quantitative-Structure Activity Relationship (QSAR) analysis to correlate in vitro anti-malarial activity against multi drug resistant strain of Plasmodium falciparum. Forty-three synthetic prodiginines with different structural features were used for their potential antimalarial activity. Linear, bilinear, biexponential and parabolic equations were developed. These equations were compared to determine the optimum values … …Current Research in Drug Discovery, Vol. 1, Issue 2 · 26 Jan 2015 · 14,146 accessesView PDFCite
Research ArticleOpen accessIn the abstractDevelopment and Optimization of Plant Extract Loaded Nanoemulsion Mixtures for the Treatment of Inflammatory DisorderMukesh Gohel, Tejal Soni, Lal Hingorani et al.In current study, a nanoemulsion as drug delivery system (NE) of spray dried Boswellia Serrata Extract (BSE) was developed and characterized to compare it in vitro/Ex vivo diffusion with reference formulation. Pseudo-ternary phase diagrams were constructed by phase diagram by aqueous titration method, of which the evaluation method was improved for solubility, Droplet size and transmittance. The formulation of BSE-loaded … …Current Research in Drug Discovery, Vol. 1, Issue 2 · 26 Jan 2015 · 14,068 accessesView PDFCite
Research ArticleOpen accessIn the abstractInfluence of Degrading Calcium Phosphate on the Remodelling and Mineralisation of Avascular Osseous Tissue in a Rat Calvaria ModelTulio Fernandez, Carlos H. Valencia, Yuann Li et al.Artificial bone graftingis the subject of intensive investigation for craniofacial reconstruction. Among the syntheticcandi date materials, those incorporating Calcium Phosphates (CaP) have gained popularity, due to their osteoinductive properties. Despite many quantitative studies on the degradation rates of CaP biomaterials in vitro, there is lack of quantitative studies in relation to bone remodelling kinetics in vivo. In this investigation, we … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 1 · 24 Dec 2014 · 7,210 accessesView PDFCite
Research ArticleOpen accessIn the abstractISOLATION AND CHARACTERIZATION OF BIFENTHRIN CATABOLIZING BACTERIAL STRAIN BACILLUS CIBI FROM SOIL FOR PYRETHROIDS BIODEGRADATIONPreeti Pandey, Geetika Pant, G. SibiPyrethroids are commonly used in most parts of the world and are reported to have potential health risks. Bifenthrin, a third generation pyrethroid used as insecticide has caused potential effect on aquatic life and human health. Bioremediation is a practical approach to reduce pesticide in the environment and reports of microbial degradation of bifenthrin are meagre. This study was aimed … …OnLine Journal of Biological Sciences, Vol. 14, Issue 3 · 15 Sep 2014 · 7,584 accessesView PDFCite
Research ArticleOpen accessIn the abstractMOLECULAR CHARACTERIZATION AND IMMUNOPROTECTIVE ACTIVITY OF CAPSULAR POLYSACCHARIDE OF KLEBSIELLA PNEUMONIAE ISOLATED FROM FARM ANIMALS AT TAIF GOVERNORATEAhmed M.A. Mansour, Hoda M. Zaki, Nibal A. Hassan, Abdulrahman A. Al-HumianyKlebsiella pneumoniae is a Gram-negative enterobacterium that has historically been and currently remains, a significant cause of human disease and several kinds of infections in animals. In the present work, trials for the isolation of Klebsiella pneumoniae from diseased and apparently healthy farm animals (cows, sheep, goats and camels) were done for recognition of Klebsiella pneumoniae subspecies. It was noticed … …American Journal of Infectious Diseases, Vol. 10, Issue 1 · 6 Jan 2014 · 7,942 accessesView PDFCite