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78 results for “genetic studies”
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Research ArticleOpen accessIn the abstractRole of Angiotensin-Converting Enzyme and Vitamin D Receptor Gene Polymorphisms in Cancer Anorexia-Cachexia SyndromeAriele Fabris, Paolo Biagioni, Tiziana Punzi et al.The ubiquitin-proteasome pathway is a crucial connection between aberrant immune system activation, systemic inflammation and Cancer Anorexia-Cachexia Syndrome (CACS), a syndrome that culminates in hyper-activation of the ubiquitin-proteasome pathway. Angiotensin directly up-regulates this pathway, while vitamin D down-regulates it indirectly through the insulin-like growth factor-1 pathway. We investigated the genetic predisposition towards CACS in a cancer population, examining Insertion/Deletion (I/D) … …American Journal of Immunology, Vol. 8, Issue 3 · 2 Aug 2012 · 9,560 accessesView PDFCite
Research ArticleOpen accessIn the abstractHigh-Order Interactions in Rheumatoid Arthritis Detected by Bayesian Method using Genome-Wide Association Studies DataJing Zhang, Zheyang Wu, Chao Gao, Michael Q. ZhangProblem statement: In order to reveal the missing genetic component of Rheumatoid Arthritis (RA) susceptibility, we carried out a genome-wide high-order epistatic interaction study for RA. Approach: A powerful Bayesian strategy was applied to analyze the data of Genome-Wide Association Studies (GWAS) from the Welcome Trust Case Control Consortium (WTCCC), where 319 high-order interactions were found across the whole genome … …Current Research in Medicine, Vol. 3, Issue 1 · 30 Mar 2012 · 8,379 accessesView PDFCite
Research ArticleOpen accessIn the abstractMaternal Infection and Neurodevelopmental Disorders in the OffspringHeping ZhouProblem statement: Neurodevelopmental disorders such as schizophrenia and autism have been attributed to both genetic and environmental factors. Whether and how maternal infection as an environmental factor contributes to the development of neurological abnormalities in the offspring remains to be clearly defined. Approach: The literature was reviewed to examine the relationship between maternal infection and neurological disorders such as schizophrenia … …American Journal of Immunology, Vol. 8, Issue 1 · 12 Mar 2012 · 8,150 accessesView PDFCite
Research ArticleOpen accessIn the abstractMorphological Characterization and Variation in the Total Content of Reducing Sugars in Wild Populations of Agave angustifolia HawMartin Esqueda, Aldo Gutierrez, Guadalupe Palomino et al.Problem statement: Bacanora, a spirit, is distilled from wild populations of Agave angustifolia Haw. Loss of biodiversity must be taken into account when proposing sustainable management actions for this resource. In this study we identified the morphological variants of this species, as well as the weight and Total Content of Reducing Sugars (TRS) in the stem of the agave. Approach: … …American Journal of Agricultural and Biological Sciences, Vol. 6, Issue 4 · 21 Oct 2011 · 8,553 accessesView PDFCite
Research ArticleOpen accessIn the abstractCharacterization of the Genetic Diversity of Peach Cultivars in Taif by RAPD-PCRMohamed A. Nagaty, Salah El-Din El-Assal, Mahmoud M. RifaatProblem statement: Peach genotypes from the Kingdom of Saudi Arabia were not adequately characterized at the biological and molecular levels. This study was carried out to characterize nine peach cultivars growing in Taif (KSA) at the biological and molecular levels. Approach: For the nine peach cultivars studied, flowering and fruiting indices were determined and eight, 10-base primers were used to … …American Journal of Applied Sciences, Vol. 8, Issue 7 · 24 Jun 2011 · 7,271 accessesView PDFCite
Research ArticleOpen accessIn the abstractEstimation of Genetic Correlations on Sweet Corn Inbred Lines Using SAS Mixed ModelPedram Kashiani, Ghizan SalehProblem statement: Genetic correlations among traits refer to the extent of relatedness among them due to genetic causes. Estimating genetic correlations for quantitative traits is tedious if done manually. Approach: However, the use of the computer software SAS, applying mixed-model analysis of variance has facilitated many recent studies in evolutionary quantitative genetics. Results: In this two-way statistical model, the variance … …American Journal of Agricultural and Biological Sciences, Vol. 5, Issue 3 · 30 Sep 2010 · 10,891 accessesView PDFCite
Research ArticleOpen accessIn the abstractMetabolic Fingerprinting of Three Malaysian Ginger (Zingiber officinale Roscoe) Using Gas Chromatography-Mass SpectromertryH.J. Mahdi, R. Andayani, IshakProblem statement: There is a chemical variation among different ginger cultivars detected by previous studies including the volatile and non-volatile oleo-resins. In this study we try to determine whether these variations are related to a genetic factor rather than environmental or intrinsic factors. Approach: A comprehensive metabolic fingerprinting from the leaves of three micro-propagated ginger cultivars Bukit Tinggi, Tanjung Sepat … …American Journal of Applied Sciences, Vol. 7, Issue 1 · 31 Jan 2010 · 7,387 accessesView PDFCite
Research ArticleOpen accessIn the abstractApplication of Statistical Procedures for Analysis of Genetic Diversity in Domestic Animal PopulationsM. R. Nassiry, A. Javanmard, Reza TohidiProblem statement: A wide range of studies for the assessment of genetic diversity in livestock breed were conducted using genetic distance. For high-accuracy and unbiased estimation sampling methods, criteria of choosing type of DNA markers, distance measurement strategies, cluster analysis will be important for any genetic diversity projects. Approach: Main objective of this short review is focusing on application statistical … …American Journal of Animal and Veterinary Sciences, Vol. 4, Issue 4 · 31 Dec 2009 · 7,646 accessesView PDFCite
Research ArticleOpen accessIn the abstractGenetic Capability of Young Layers for Survival after Salmonella entritidis ChallengeE. S. Soliman, H. Busby, C. Kilpatrick et al.Problem statement: Genetic line differences in resistance of layer hens and young chicks to Salmonella entritidis have been identified through a lot of studies. That is why the agricultural industry was prepared for the potential phasing out of antibiotics for use in controlling bacterial pathogens. Early infection may result in long term colonization of layers with Salmonella entritidis, resulting in … …American Journal of Applied Sciences, Vol. 6, Issue 10 · 31 Oct 2009 · 6,780 accessesView PDFCite
Research ArticleOpen accessIn the abstractOn the Predictability of Risk Box Approach by Genetic Programming Method for Bankruptcy PredictionAlireza Bahiraie, Noor Akma bt Ibrahim, A. K.M. AzharProblem statement: Theoretical based data representation is an important tool for model selection and interpretations in bankruptcy analysis since the numerical representation are much less transparent. Some methodological problems concerning financial ratios such as non-proportionality, non-asymetricity, non-scalicity are solved in this study and we presented a complementary technique for empirical analysis of financial ratios and bankruptcy risk. Approach: This study … …American Journal of Applied Sciences, Vol. 6, Issue 9 · 30 Sep 2009 · 7,948 accessesView PDFCite