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79 articles for “effective dose”
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Research ArticleOpen accessIn the abstractAssessment of the Annona muricata Leaf Ethanol Extract Effect on The Diameter of Pancreatic Islets in Alloxan-Induced MiceSyafira N. Dewi, Supri I. Handayani, Marini Stephanie et al.Diabetes mellitus is one of a non-communicable disease whose prevalence continues to increase from year to year in both developed and developing countries. In Indonesia, it is estimated that 12 million people aged ≥15 years old had diabetes mellitus in 2013. Treatment of diabetes mellitus by using plant extract has been reported to have good results. One of the plants … …OnLine Journal of Biological Sciences, Vol. 20, Issue 1 · 9 Mar 2020 · 8,065 accessesView PDFCite
Review ArticleOpen accessIn the abstractImmune Metabolism in Functional Aspects of the BrainElisa Gonzalez Cuevas, Nitya G. ChakrabortyThe brain interacts with the immune system in a highly regulated and restricted manner. Immune signals initiate pro- and anti-inflammatory activity in most body tissues in response to disease states and injury. An accumulation of inflammatory insults can disrupt immune metabolic homeostasis and give rise to pathology in sensitive areas. Here, we provide an overview of interactions between immune metabolism … …American Journal of Immunology, Vol. 15, Issue 1 · 18 Dec 2019 · 7,222 accessesView PDFCite
Research ArticleOpen accessIn the abstractDetermination of the Probiotic Potential and Metabolic Function of Lactobacillus Strains for Healthy Calf RearingRaya Myktybayeva, Serkan Özkaya, Elif Rabia Şanlı et al.This research investigstes the impact of probiotic supplementation on the growth performance, health status, and physiological traits in Holstein calves. A total of thirty calves were randomly divided into three experimental groups: a control group and two treatment groups receiving probiotics at doses of 1 g/10 kg and 1.5gt/10 kg live weight. Key indicators, including Live Weight (LW), Body Measurements … …OnLine Journal of Biological Sciences, Vol. 25, Issue 3 · 23 Jul 2025 · 3,635 accessesView PDFCite
Research ArticleOpen accessIn the abstractAmeliorative Impacts of Tribulus terrestris Against Ivermectin-Induced Hepato-Renal Toxicity in Rabbit: Pharmacological and Histopathological StudySally I. Ismaiel, Sameh M. Farouk, Raafat A. El-Ramady, Waleed F. KhalilThe current work aimed to investigate the protective effects of Tribulus terrestris extracts against ivermectin-induced hepatic and renal toxicity in male rabbit. Selenium plus vitamin E was used as a comparative standard drug to evaluate the efficacy of Tribulus terrestris extract on some hematological parameters, kidney and liver enzymes as well as associated histopathological changes. This work was carried out … …American Journal of Animal and Veterinary Sciences, Vol. 12, Issue 1 · 12 Jan 2017 · 7,771 accessesView PDFCite
Research ArticleOpen accessIn the abstractRoboBrew: The Fully Autonomous Coffee MachineAnthony Achkar, Maroun Hannoun, Rita Younes et al.Robotics has emerged in several domains in the current century. However, in the restoration field, mainly in coffee shops, applications are still limited. Therefore, RoboBrew presents a groundbreaking fully automated system poised to transform the restaurant and coffee industries into a new era. At its core, RoboBrew features an advanced coffee maker system designed to deliver exceptional performance. This system … …Journal of Mechatronics and Robotics, Vol. 8, Issue 1 · 1 Oct 2024 · 8,520 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of a Phytomineral Complex and an Enzyme Preparation on the Absorption of Nutrients and the Energy Balance of Calves' DietEvgeniia Erenko, Aleksandr Ovchinnikov, Marat Aubakirov et al.Cost-effective animal husbandry directly depends on the correct breeding of replacement young animals using diets corresponding to the feeding rate for all nutrition elements of the detailed system. Critical to these diets are biogenic elements, pivotal in enzymatic reactions and immune defense. However, specifics on enhancing nutrient absorption through dietary supplements remain underexplored, particularly in the context of calves' preweaning … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 12 Jun 2024 · 4,595 accessesView PDFCite
Review ArticleOpen accessIn the abstractThe Exposure of Pesticides to Honeybees: A Global Threat to Food SecurityHalima Sadia, Pratik Raj Karki, Mansura Afroz et al.The pivotal role of honeybees as global pollinators underscores their significance in ecological and agricultural systems. However, the beekeeping industry faces a significant challenge due to the improper utilization of pesticides, resulting in adverse effects on honeybee populations. This comprehensive review endeavors to investigate the toxicity of pesticides to honeybees, examining the various routes of exposure. Furthermore, it aims to … …OnLine Journal of Biological Sciences, Vol. 24, Issue 2 · 20 Jan 2024 · 6,061 accessesView PDFCite
Research ArticleOpen accessIn the abstractProposed Insights in the Pharmaco-Dynamic Theory of Ascorbate Pro-Oxidant ActivityKheir Eddine Kerboua, Fatma Haiba, Fatima Bendjemia et al.Ascorbate pro-drug theory promising possible effective and nontoxic treatment is intensively examined and centered on the importance of both extracellular and intra-cellular effects of ascorbate. In this study, we sought to determine the in vitro cell responsiveness in a plasma free milieu with or without an extracellular catalyst and/or hydrogen peroxide. This project brought to light how ascorbic acid would … …OnLine Journal of Biological Sciences, Vol. 16, Issue 1 · 24 Nov 2015 · 6,969 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntibacterial and Anti-Quorum Sensing Activities of Selected Italian Honeys against Antibiotic-Resistant PathogensMarco Fidaleo, Roberto Lavecchia, Antonio ZuorroThree nectar honeys (eucalyptus, thyme and forest) and two honeydew honeys (fir and Metcalfa) from Italy were tested for their antibacterial activity against pathogens commonly associated with wound and burn infections, including Methicillin-Resistant Staphylococcus Aureus (MRSA), methicillin-resistant Staphylococcus epidermidis (MRSE) and Vancomycin-Resistant Enterococcus Faecalis (VREF). All honeys showed bactericidal activity against the microorganisms used, with honeydew honeys being the most … …OnLine Journal of Biological Sciences, Vol. 15, Issue 4 · 27 Oct 2015 · 7,052 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Combined Fenofibrate and Nicotinamide on Oxidative Stress and Inflammatory Cytokines Involved in Cisplatin-Induced Nephrotoxicity in RatsOmaima M. Abd Allah, Abeer A.I. Sharaf El-Din, Fouad El DebakeyCisplatin (Cis) is an anticancer drug, which is accompanied with major side effects including nephrotoxicity. The current study was performed to assess the possible prophylactic effects of fenofibrate (FEN), Nicotinamide (NAM) and their combination on oxidative stress and inflammatory cytokines associated with cisplatin-induced renal damage. Rats were randomly divided into seven groups (8 each) as follows; control group; FEN group … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 4 · 9 Jan 2015 · 7,131 accessesView PDFCite