Sign inSubmit
Tips: “quotes” for a phrase · author:Lee · a DOI goes straight to its article

79 results for “effective dose”
Set a search alert
Research ArticleOpen accessIn the abstractAssessment of the Annona muricata Leaf Ethanol Extract Effect on The Diameter of Pancreatic Islets in Alloxan-Induced MiceSyafira N. Dewi, Supri I. Handayani, Marini Stephanie et al.Diabetes mellitus is one of a non-communicable disease whose prevalence continues to increase from year to year in both developed and developing countries. In Indonesia, it is estimated that 12 million people aged ≥15 years old had diabetes mellitus in 2013. Treatment of diabetes mellitus by using plant extract has been reported to have good results. One of the plants … …OnLine Journal of Biological Sciences, Vol. 20, Issue 1 · 9 Mar 2020 · 8,061 accessesView PDFCite
Review ArticleOpen accessIn the abstractImmune Metabolism in Functional Aspects of the BrainElisa Gonzalez Cuevas, Nitya G. ChakrabortyThe brain interacts with the immune system in a highly regulated and restricted manner. Immune signals initiate pro- and anti-inflammatory activity in most body tissues in response to disease states and injury. An accumulation of inflammatory insults can disrupt immune metabolic homeostasis and give rise to pathology in sensitive areas. Here, we provide an overview of interactions between immune metabolism … …American Journal of Immunology, Vol. 15, Issue 1 · 18 Dec 2019 · 7,219 accessesView PDFCite
Research ArticleOpen accessIn the abstractAmeliorative Impacts of Tribulus terrestris Against Ivermectin-Induced Hepato-Renal Toxicity in Rabbit: Pharmacological and Histopathological StudySally I. Ismaiel, Sameh M. Farouk, Raafat A. El-Ramady, Waleed F. KhalilThe current work aimed to investigate the protective effects of Tribulus terrestris extracts against ivermectin-induced hepatic and renal toxicity in male rabbit. Selenium plus vitamin E was used as a comparative standard drug to evaluate the efficacy of Tribulus terrestris extract on some hematological parameters, kidney and liver enzymes as well as associated histopathological changes. This work was carried out … …American Journal of Animal and Veterinary Sciences, Vol. 12, Issue 1 · 12 Jan 2017 · 7,766 accessesView PDFCite
Research ArticleOpen accessIn the abstractDetermination of the Probiotic Potential and Metabolic Function of Lactobacillus Strains for Healthy Calf RearingRaya Myktybayeva, Serkan Özkaya, Elif Rabia Şanlı et al.This research investigstes the impact of probiotic supplementation on the growth performance, health status, and physiological traits in Holstein calves. A total of thirty calves were randomly divided into three experimental groups: a control group and two treatment groups receiving probiotics at doses of 1 g/10 kg and 1.5gt/10 kg live weight. Key indicators, including Live Weight (LW), Body Measurements … …OnLine Journal of Biological Sciences, Vol. 25, Issue 3 · 23 Jul 2025 · 3,626 accessesView PDFCite
Research ArticleOpen accessIn the abstractProposed Insights in the Pharmaco-Dynamic Theory of Ascorbate Pro-Oxidant ActivityKheir Eddine Kerboua, Fatma Haiba, Fatima Bendjemia et al.Ascorbate pro-drug theory promising possible effective and nontoxic treatment is intensively examined and centered on the importance of both extracellular and intra-cellular effects of ascorbate. In this study, we sought to determine the in vitro cell responsiveness in a plasma free milieu with or without an extracellular catalyst and/or hydrogen peroxide. This project brought to light how ascorbic acid would … …OnLine Journal of Biological Sciences, Vol. 16, Issue 1 · 24 Nov 2015 · 6,966 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntibacterial and Anti-Quorum Sensing Activities of Selected Italian Honeys against Antibiotic-Resistant PathogensMarco Fidaleo, Roberto Lavecchia, Antonio ZuorroThree nectar honeys (eucalyptus, thyme and forest) and two honeydew honeys (fir and Metcalfa) from Italy were tested for their antibacterial activity against pathogens commonly associated with wound and burn infections, including Methicillin-Resistant Staphylococcus Aureus (MRSA), methicillin-resistant Staphylococcus epidermidis (MRSE) and Vancomycin-Resistant Enterococcus Faecalis (VREF). All honeys showed bactericidal activity against the microorganisms used, with honeydew honeys being the most … …OnLine Journal of Biological Sciences, Vol. 15, Issue 4 · 27 Oct 2015 · 7,050 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Combined Fenofibrate and Nicotinamide on Oxidative Stress and Inflammatory Cytokines Involved in Cisplatin-Induced Nephrotoxicity in RatsOmaima M. Abd Allah, Abeer A.I. Sharaf El-Din, Fouad El DebakeyCisplatin (Cis) is an anticancer drug, which is accompanied with major side effects including nephrotoxicity. The current study was performed to assess the possible prophylactic effects of fenofibrate (FEN), Nicotinamide (NAM) and their combination on oxidative stress and inflammatory cytokines associated with cisplatin-induced renal damage. Rats were randomly divided into seven groups (8 each) as follows; control group; FEN group … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 4 · 9 Jan 2015 · 7,128 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Leptospirosis on the Concentrations of Streptomycin in Liver and Kidneys of PigsLabrini V. Athanasiou, Vassilios Papatsiros, George Valiakos et al.Leptospirosis is a re-emerging infectious disease with zoonotic potential. Pigs are reservoir hosts of the pathogen and streptomycin is among the antibiotics proposed to eliminate leptospiral infection. The purpose of this study was to determine streptomycin concentrations and the possible effect of the presence of Leptospira in the liver and kidneys on drug distribution. Six pigs with leptospirosis and six … …American Journal of Animal and Veterinary Sciences, Vol. 8, Issue 1 · 28 Mar 2013 · 7,485 accessesView PDFCite
Research ArticleOpen accessIn the abstractKEY PARAMETERS OF MEASLES VIRUS PRODUCTION FOR ONCOLYTIC VIROTHERAPYK. Weiss, D. Salzig, M. D. Mühlebach et al.Attenuated measles virus has revealed selective tumor cell killing and is currently tested in clinical trials for the therapy of cancer patients. The amount of infectious particles per dose needed for oncolytic therapy can be more than a million times higher compared to vaccination. This requires highly effective production processes which guarantee the measles virus quantities needed for its use … …American Journal of Biochemistry and Biotechnology, Vol. 8, Issue 2 · 22 Jun 2012 · 9,785 accessesView PDFCite
Research ArticleOpen accessIn the abstractMoringa oleifera Leaves Extract Attenuates Neuropathic Pain Induced by Chronic Constriction InjuryJurairat Khongrum, Jintanaporn Wattanathorn, Supaporn Muchimapura et al.Problem statement: Neuropathic pain, a challenge of this decade, has been reported to be associated with the diversity conditions including diabetes. At present, there are no conventional analgesics that can effectively treat neuropathic pain with a satisfactory outcome. Due to the limitation of therapeutic efficacy, the searching for novel effective remedies in the management of neuropathic pain is required. Approach: … …American Journal of Applied Sciences, Vol. 9, Issue 8 · 18 Jun 2012 · 17,239 accessesView PDFCite