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734 results for “Th Cells”
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Research ArticleOpen accessEvery word in the titleThe Role of Treg Cells in the Cancer Immunological ResponseZhi-Zhang Yang, Stephen M. AnsellProblem statement: T cell-mediated immunosuppression has been observed for decades without clarification as to which factor was responsible for this observation. The identification of CD4+CD25+ regulatory T (Treg) cells represents a milestone in the filed of immunology and provides an explanation for T-cell-mediated immunosuppression. Although Treg cells were originally identified for their ability to prevent organ-specific autoimmune disease in mice, … …American Journal of Immunology, Vol. 5, Issue 1 · 31 Mar 2009 · 8,524 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAn Efficient Production of Oligosaccharides by a Reaction using Whole Mammalian Cells as BiocatalystsTomohisa Kato, Rie Mitsumori, Kenichi HatanakaProblem statement: Mammalian cells were used for the production of oligosaccharides by saccharide primer method. However, because cells in culture are used, productivity of oligosaccharides is low. Approach: In saccharide primer method employing cells under culture, glycosylation was performed only by mixing the collected cells in reaction mixtures. Saccharide primer, 12-azidododecyl β-lactoside that mimics lactosylceramide (LacCer), was incubated with various … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 4 · 31 Dec 2008 · 6,441 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEffects of D- and L-Glucose and Mannitol on Retinal Capillary Cells: Inhibition by Nanomolar AminoguanidineYongxin Yu, Wei Li, Barbara Wojciechowski et al.Hyperglycemia may contribute directly to pericyte loss and capillary leakage in early diabetic retinopathy. To elucidate relative contributions of glycation, glycoxidation, sugar autoxidation, osmotic stress and metabolic effects in glucose-mediated capillary damage, we tested the effects of D-glucose, L-glucose, mannitol and the potentially protective effects of aminoguanidine on cultured bovine retinal capillary pericytes and endothelial cells. Media (containing 5 mM … …American Journal of Pharmacology and Toxicology, Vol. 2, Issue 4 · 31 Dec 2007 · 7,751 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleCo-expression of Apoptosis-Related Molecules on Activated CD8+ CD38+ T-cells is Associated with HIV-1 Disease ProgressionJosé W. Rodríguez, Luis A. Rodríguez, Griselle Font et al.CD8+ T cells play a major role in controlling HIV-1 infection through the release of soluble lytic and non-lytic antiviral factors. Their decrease or defective function contributes to the HIV-1 disease progression. HIV-1 disease progression has been associated with a remarkable increase of CD38 expression on CD8+ T-cells. It has been also documented that a significant distribution of HIV-specific CD8+T-cells … …American Journal of Infectious Diseases, Vol. 3, Issue 4 · 31 Dec 2007 · 7,016 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleSuppression of Basal and Cytokine Induced Expression of MHC, ICAM 1 and B7 Markers on Mouse Lung Epithelial Cells Exposed to Diesel Exhaust ParticlesRajiv K. Saxena, Wanda Williams, M. Ian GilmourDiesel exhaust particles (DEP) constitute a significant component of airborne particulates in urban environment. Exposure to DEP is known to enhance susceptibility to viral and bacterial infections. We hypothesized that DEP could partially exert its effect on disease susceptibility by interfering with antigen presentation required for the generation of protective adaptive immune responses. MHC class I and class II molecules, … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 4 · 31 Dec 2007 · 6,610 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAn Ultrastructural Study of Endoplasmic Reticulum of Mammary Secretory Cells in Rabbits During Lactation and Regression StagesSvatoslav Hluchy, Robert TomanThe objective of the research was to study the changes of the Endoplasmic Reticulum (ER) in mammary epithelial cells of rabbits during lactation and regression stages. Our results using conventional transmission electron microscopy has shown that ER is changed during the various mammary gland development stages. We found that the average relative volume of ER achieves 17.7±2.464% of cytoplasm volume … …American Journal of Animal and Veterinary Sciences, Vol. 9, Issue 4 · 15 Dec 2014 · 7,326 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleDEVELOPMENT OF A FUZZY-SIMULATION MODEL OF SCHEDULING ROBOTIC FLEXIBLE ASSEMBLY CELLSKhalid Abd, Kazem Abhary, Romeo MarianDue to the complexity of scheduling flexible manufacturing systems, the generation of production schedules requires an intelligent technique. Many artificial intelligence techniques such as fuzzy logic, genetic algorithms and neural networks have been successfully applied to the scheduling of advanced manufacturing systems. One such system is Robotic Flexible Assembly Cells (RFACs). Few studies have addressed the problem of scheduling RFACs. … …Journal of Computer Science, Vol. 9, Issue 12 · 25 Nov 2013 · 6,796 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleNatural Sensitizer for Dye-Sensitized Solar Cells Using Three Layers of Photoelectrode Thin Films with a Schottky BarrierHo Chang, Mu-Jung Kao, Tien-Li Chen et al.Problem statement: This study combines Au nanoparticles with TiO2 nanoparticles to form a Schottky barrier and applies it to the photoelectrode thin film of Dye-Sensitized Solar cells (DSSCs). Approach: First, commercial TiO2 powder (Degussa P25) was put into the alkaline solution to prepare TiO nanotubes (Tnt) by a hydrothermal process. Tnt were sintered at 550° to obtain TntC550 particles and … …Current Research in Nanotechnology, Vol. 1, Issue 1 · 15 Jun 2011 · 7,990 accessesView PDFCite
Review ArticleOpen accessEvery word in the titleOverview of Vascular Smooth Muscle Cells, Endothelial Cells, and Macrophages Apoptosis During Atherosclerosis DevelopmentAnastasia Vladimirovna Poznyak, Varvara Alexandrovna Orekhova, Vasily Nikolaevich Sukhorukov et al.Atherosclerosis is a complex disease that has garnered significant attention from researchers studying its various aspects. Its pathogenesis involves a wide array of cellular and molecular components, as well as crucial mechanisms and processes crucial for cellular and organismal functioning. Atherosclerosis is considered a chronic inflammatory disease characterized by disrupted lipid metabolism, oxidative stress, and immune response. Apoptosis, a fundamental … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 5 Jul 2024 · 4,677 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleInterleukin 10 Induces the Maturation of Putative Tolerogenic Monocyte-derived Dendritic Cells as Revealed by GeneArray AnalysisMarianne A. Jakobsen, Bjarne K. MØller, Klaus Rieneck et al.IL-10 is a multifunctional cytokine with known inhibitory effect on DC maturation. In the present study, we show that the presence of IL-10 during the first 6 days of maturation of Mo-DC has severe effects on the phenotype with IL-10 treated Mo-DC retaining a high expression of factors involved in antigen uptake and having low expression of costimulatory factors and … …American Journal of Immunology, Vol. 1, Issue 4 · 31 Dec 2005 · 6,626 accessesView PDFCite