82 results for “Side effects”

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Research ArticleOpen accessIn the abstractEffect of Combined Fenofibrate and Nicotinamide on Oxidative Stress and Inflammatory Cytokines Involved in Cisplatin-Induced Nephrotoxicity in RatsOmaima M. Abd Allah, Abeer A.I. Sharaf El-Din, Fouad El DebakeyCisplatin (Cis) is an anticancer drug, which is accompanied with major side effects including nephrotoxicity. The current study was performed to assess the possible prophylactic effects of fenofibrate (FEN), Nicotinamide (NAM) and their combination on oxidative stress and inflammatory cytokines associated with cisplatin-induced renal damage. Rats were randomly divided into seven groups (8 each) as follows; control group; FEN group … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 4 · 9 Jan 2015 · 7,131 accessesView PDF Cite

Research ArticleOpen accessIn the abstractSerum TGF-β and TNF-α During Psoriasis Therapy with Narrowband Ultraviolet BAhmad Taha Khalaf, Yan YuehuaAlthough it is now an accepted concept that narrow-band UVB therapy is an efficacious therapy for psoriasis, the relationship between the response rate and the potential effects on serum cytokines is less well-established. The purpose of this study was to investigate the correlation between the response rate and the changes of serum TGF-β and TNF-α necessary for understanding the underlying … …American Journal of Applied Sciences, Vol. 11, Issue 12 · 6 Jan 2015 · 6,095 accessesView PDF Cite

Research ArticleOpen accessIn the abstractEvaluation of Neuropharmacological Activities of Stephania venosa Herb Consumption in Healthy RatsTerdthai Tong-Un, Wathita Phachonpai, Supaporn Muchimapura et al.Public concern on mental health has noticeably increased given the high prevalence of neuropsychiatric disorders especially anxiety and depression. Most of the drugs for these conditions used nowadays have adverse side effects so the need for newer, better-tolerated and more efficacious treatments is remaining high. Growing attention is being paid to traditional herbal medicines. Stephania venosa Spreng (S. venosa; SV) … …American Journal of Agricultural and Biological Sciences, Vol. 7, Issue 3 · 5 Jul 2012 · 7,679 accessesView PDF Cite

Research ArticleOpen accessIn the abstractStudy of Electromagnetic Radiation and Specific Absorption Rate of Mobile Phones with Fractional Human Head Models via Green's FunctionsNookala Srinivasa Rao, G. R. Babu, P. V.S. SrinivasProblem statement: Electromagnetic Radiation from mobile hand set is identified as one of the side effects for increasing rate of brain tumor. Due to this reason, Mobile phone industries are attentive towards safety issues of human health. Specific Absorption Rate is one of the important parameter while modeling the radiation effect on human head. Brain material with homogeneity is treated … …Journal of Computer Science, Vol. 7, Issue 8 · 16 Jul 2011 · 6,701 accessesView PDF Cite

Research ArticleOpen accessIn the abstractEffects of Complexing Agent on Electrochemical Micro Machining of Stainless SteelChen Hui, Wang Yu-Kui, Wang Zhen-Long, Zhao Wan-ShengProblem statement: Electrochemical Machining (ECM) is a prospective technique in micro machining. The productions of work piece in ECM are precipitation of hydroxide, which will block the machining gap. To prevent the formation of hydroxide, acids were often used. To machining work piece which is not acid-resistant, acids are not suitable. Approach: This study is conducted to find the effects … …Current Research in Nanotechnology, Vol. 1, Issue 1 · 15 Jun 2011 · 7,120 accessesView PDF Cite

Research ArticleOpen accessIn the abstractQuercetin Liposomes via Nasal Administration Reduce Anxiety and Depression-Like Behaviors and Enhance Cognitive Performances in RatsTerdthai Tong-Un, Panakaporn Wannanon, Jintanaporn Wattanathorn, Wathita PhachonpaiProblem statement: At present, the prevalence of neuropsychological disorders particularly anxiety, depression and dementia are increase. Many strategies have been developed in order to increase the efficiency of treatment and decrease side effects. Oxidative stress has been reported to play an important role on various path physiological states. Quercetin is a flavonoid commonly found in fruits and vegetables. It has … …American Journal of Pharmacology and Toxicology, Vol. 5, Issue 2 · 30 Jun 2010 · 9,036 accessesView PDF Cite

Research ArticleOpen accessIn the abstractAnti-Inflammatory Activity of Vitex leucoxylon L. Bark Extracts Against Freund's Complete Adjuvant Induced Arthritis in Sprague Dawley RatAlluri V. Krishnaraju, Chundi B.M. Rao, Dodda Sundararaju et al.Problem statement: Anti-inflammatory agents, particularly steroids and cyclooxygenase inhibitors are often associated with adverse side effects including, GI irritation, ulcers, hypertension and cardiac abnormalities. A safe and effective intervention is essential for the treatment of inflammatory disorders. Approach: Abstract Vitex leucoxylon L., a medicinal plant of the verbenaceae family, used in traditional medicine for relieving headache and catarrh. VL-89/185A, was … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 8,047 accessesView PDF Cite

Research ArticleOpen accessIn the abstractEffect of Adding Dexmedetomidine versus Fentanyl to Intrathecal Bupivacaine on Spinal Block Characteristics in Gynecological Procedures: A Double Blind Controlled StudySubhi M. Al-Ghanem, Islam M. Massad, Mahmoud M. Al-Mustafa et al.Problem statement: The purpose of this study was to evaluate the onset and duration of sensory and motor block as well as operative analgesia and adverse effects of Dex Metedo Midine (DXM) or fentanyl given intrathecally with plain 0.5% bupivacaine for spinal anesthesia. Approach: seventy six patients classified as American Society of Anesthesiologists (ASA) status I, II and III scheduled … …American Journal of Applied Sciences, Vol. 6, Issue 5 · 31 May 2009 · 14,177 accessesView PDF Cite

Research ArticleOpen accessIn the abstractExperimental Modeling of Pile-Leg Interaction in Jacket Type Offshore Platforms Cyclic Inelastic BehaviorM.R. Honarvar, M.R. Bahaari, B. AsgarianOffshore platforms in seismically active areas should be designed to survive in the event of severe ground excitations with no global structural failure. The annulus between the pile and leg in jacket-type offshore platforms can be filled with cement grout as a means of reducing horizontal deflections, inhibiting corrosion and preventing local damages. This paper discusses an experimental approach which … …American Journal of Applied Sciences, Vol. 5, Issue 11 · 30 Nov 2008 · 7,009 accessesView PDF Cite

Research ArticleOpen accessIn the abstractNarrow-band ultraviolet B and Conventional UVB phototherapy in Psoriasis: a Randomised Controlled TrialYan Yuehua, Ahmad T. Khalaf, Zhai Xiaoxiang, Wang XinggangThe narrow-band (NB-UVB) was developed for use in phototherapy, as an alternative to a broad-band UVB source and to photochemotherapy, both of which have significant side effects and carry a risk of carcinogenesis. NB-UVB is a new phototherapy option that has proved to be particularly effective at clearing psoriasis vulgaris, with a reduced capacity to produce erythema. This study was … …American Journal of Applied Sciences, Vol. 5, Issue 8 · 31 Aug 2008 · 6,953 accessesView PDF Cite