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62 articles for “R.J.A. Richard”
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Research ArticleOpen accessIn the author namesEnvironmental Factors and Limbic Vulnerability in Childhood AutismRichard LatheThe rise in prevalence of autism spectrum disorders (ASD) is suggestive of a new etiology. Diagnostic substitution alone is unlikely to account for the increase, while genetic association with detoxification gene alleles points to an environmental contribution. Subtle structural anomalies in the ASD brain are widespread but limbic damage seems important for the development of behaviors diagnostic of ASD. The … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 2 · 30 Jun 2008 · 7,680 accessesView PDFCite
Research ArticleOpen accessIn the author namesLoss of Morphine-induced Suppression of NK Cell activity and T-cell Functions in µ-Opioid Receptor Knockout MiceRichard J. Weber, Ricardo Gomez-Flores, Ichiro Sora, George R. UhlIn vivo administration of µ-opioid receptor selective agonists to various species is known to suppress lymphocyte, NK cell, and macrophage functions, in addition to mediate pain relief and euphoria. Using a mouse model in which the µ-opioid receptor gene was disrupted by targeted homologous recombination, we explored the involvement of this receptor in natural killer (NK) cell activity and T … …American Journal of Immunology, Vol. 2, Issue 2 · 30 Jun 2006 · 6,941 accessesView PDFCite
Research ArticleOpen accessIn the author namesIn vitro Activation of Human and Rat Lymphocyte and Macrophage Functions by NorepinephrineRicardo Gomez-Flores, Diana Caballero-Hernandez, Richard J. Weber et al.Norepinephrine (NE) has been associated not only with increasing blood pressure, atherosclerosis, heart disease, and other life threatening conditions, but also with altering immune responses by influencing leukocyte functions. In the present study, we evaluated the in vitro effects of NE on rat thymic lymphocyte and human peripheral blood mononuclear cells (HPBMC) functions. We observed that NE marginally, but significantly … …American Journal of Immunology, Vol. 1, Issue 4 · 31 Dec 2005 · 7,078 accessesView PDFCite
Research ArticleOpen accessIn the author namesNoninvasive Environmental Monitoring of Mercury in Alaskan ReindeerLawrence K. Duffy, Richard J. Hallock, Greg Finstad, R. T. BowyerReindeer, Rangifer tarandus, are terrestrial herbivores used by Alaskan Native herders for both subsistence food and commercial export. Reindeer are a renewable resource and as part of the food system are monitored for Mercury (Hg) levels in relation to the changing Arctic environment. In this study, both free-ranging reindeer from the Seward Peninsula, Alaska, and reindeer reared at the University … …American Journal of Environmental Sciences, Vol. 1, Issue 4 · 31 Dec 2005 · 6,746 accessesView PDFCite
Research ArticleOpen accessIn the author namesA General Probability Distribution Using Burmann Power SeriesRichard F. Patterson, Pali SenThe goal of this study is to present a general power series distribution that exhibits the properties of some well known distributions. To accomplish this goal we examine an infinite sequence of independent random variables having a Bürmann’s power series distribution. Consequently, we derive moment generating function of the distribution and establish the maximum likelihood estimate of the component that … …Journal of Mathematics and Statistics, Vol. 1, Issue 3 · 30 Sep 2005 · 6,295 accessesView PDFCite
Research ArticleOpen accessIn the author namesA Feasibility Study of Challenges and Opportunities in Computational Biology: A Malaysian PerspectiveR. J.A. Richard, N. SriraamThe term computational biology refers to the knowledge derived from a computer analysis of biological data that includes identification of genes in DNA sequence of different organisms, prediction of structural and functional mechanism of proteins, feature extraction and classification of genomics and proteomics. Computational biology is a rapidly developing branch of science and is highly interdisciplinary, using techniques and Concepts … …American Journal of Applied Sciences, Vol. 2, Issue 9 · 30 Sep 2005 · 6,931 accessesView PDFCite
Research ArticleOpen accessIn the author namesKorovkin and Weierstrass Approximation via Lacunary Statistical SequencesRichard F. Patterson, Ekrem SavaşIn this study we shall extended Korovkin and Weierstrass approximation theorem to lacunary statistical convergent sequences. In addition, to these approximation theorems, we established also introduced lacunary statistically convergent of degree β and establish a corresponding Korovkin type theorem namely the following: If the sequence of positive linear operators Pn: CM [a, b]→ B[a, b] satisfies the conditions: * ||Pn(1, … …Journal of Mathematics and Statistics, Vol. 1, Issue 2 · 30 Jun 2005 · 6,668 accessesView PDFCite
Research ArticleOpen accessIn the author namesMorphing Mechanisms Part 2: Using Repetitive Control to Morph Cam Follower MotionNonglak Phetkong, Meng-Sang Chew, Richard W. LongmanThis research utilizes the repetitive control approach in morphing a high-speed cam mechanism so that its output displacement tracks the desired output trajectory. The main objective is to reduce the output tracking error, which is the difference between the actual and desired output displacements of the output mass. A 3-degree of freedom mathematical model is used to analyze and represent … …American Journal of Applied Sciences, Vol. 2, Issue 5 · 31 May 2005 · 7,373 accessesView PDFCite
Research ArticleOpen accessIn the author namesMorphing Mechanisms Part 1: Using Iterative Learning Control to Morph Cam Follower MotionNonglak Phetkong, Meng-Sang Chew, Richard W. LongmanThis study introduces the concept of morphing mechanisms. Mechanisms are normally designed for specific operating conditions and once they are built one may wish to use them under different operating conditions. In some cases, a mechanism may be imperfectly fabricated and one would like to get the intended ideal performance. In these cases, instead of designing, fabricating and replacing the … …American Journal of Applied Sciences, Vol. 2, Issue 5 · 31 May 2005 · 6,840 accessesView PDFCite
Research ArticleOpen accessIn the author namesA Model for the CD4 Cell Counts in an HIV/AIDS Patient and its Application in Treatment InterventionsRichard O. Simwa, Joseph Y.T. MugishaThe number of CD4 white blood cells has been established as an important clinical marker of disease progression to acquired immunodeficiency syndrome (AIDS) for persons infected with human immunodeficiency virus (HIV). The number of CD4 cells per unit volume is expected to decrease with time since infection by the virus. However on introduction of treatment interventions, the process is expected … …American Journal of Infectious Diseases, Vol. 1, Issue 1 · 31 Mar 2005 · 6,848 accessesView PDFCite