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58 articles for “Prognosis”
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Research ArticleOpen accessIn the abstractP53 Gene: Mutation and Immunohistochemical Analysis in Patients with Invasive Ductal Carcinoma of BreastShinjini Singh, Sandeep Kumar Rajput, Mritunjai Singh et al.The p53 tumor suppressor gene is the most commonly mutated gene in cancer. In breast cancer, the presence of p53 gene alterations has been associated with worse prognosis. This study was attempted to associate p53 gene mutations with its protein expression in North Eastern Indian population. We used single-stranded conformation polymorphism to screen samples for mutations in five conserved regions, … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 4 · 20 Dec 2013 · 7,244 accessesView PDFCite
Research ArticleOpen accessIn the abstractIMMUNOHISTOCHEMICAL ANALYSIS OF UROTHELIAL BLADDER CANCERSKatarina Bevizova, Jan Jakubovsky, Jan Luha et al.Malignant cancers of urinary bladder are the second most common malignancy of the urinary tract and the fourth most common malignancy in general, especially in men. The aim of this study was a retrospective analysis of selected markers (p53, Ki-67 and E-cadherin) of urinary bladder cancers from the Department of Urology in Bratislava, Slovak Republic between years 2007 and 2009. … …OnLine Journal of Biological Sciences, Vol. 13, Issue 2 · 17 Jul 2013 · 7,372 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Role of Inflammation in Development and Therapy of Malignant MesotheliomaArti Shukla, Jill MillerMalignant Mesothelioma (MM) is an asbestos related malignancy with a poor prognosis and limited therapeutic approaches. The pathogenesis of MM has been linked to asbestos induced inflammation. Asbestos exposure results in reactive oxygen species generation, infiltration of inflammatory cells and prolonged release of multiple cytokines, oxidants and growth factors. The role of inflammation in MM has led to the evaluation … …Current Research in Medicine, Vol. 3, Issue 2 · 30 Aug 2012 · 7,437 accessesView PDFCite
Research ArticleOpen accessIn the abstractRamsay Hunt Syndrome: Case ReportJuliana Oliveira Freitas Silveira, Fernanda Schettini de Oliveira, Yanes Brum Bello et al.Problem statement: Ramsay Hunt syndrome is characterized by peripheral facial palsy and eruptions in external ear reportedly due to the reactivation of latent varicela zoster virus in the sensory ganglia of facial nerve. Our purpose is to describe a case of this syndrome accompanied by the Neurology Service of Nova Iguacu General Hospital. Approach: A 60-year old female patient sought … …Current Research in Medicine, Vol. 3, Issue 2 · 30 Aug 2012 · 8,241 accessesView PDFCite
Research ArticleOpen accessIn the abstractSchizencephaly: Case ReportJuliana Oliveira Freitas Silveira, Fernanda Schettini de Oliveira, Fernanda Arrua Vares et al.Problem statement: Whereas schizencephaly is a malformation of cortical development which exact cause remains unknown, is almost entirely characterized by clefts extending from the pial surface to ependymal surface and could be unilateral or bilateral. Oftentimes, it also occurs in association with other abnormalities. Over the years, two types were described in literature, lips closed and open. Therefore, our intention … …Current Research in Medicine, Vol. 3, Issue 2 · 28 Aug 2012 · 8,184 accessesView PDFCite
Research ArticleOpen accessIn the abstractCoronary Endothelial Dysfunction after Drug-Eluting Stent ImplantationShigenori ItoProblem statement: Stent thrombosis, which may occur even one year after stent implantation, is a drawback of Drug-Eluting Stents (DES). Among the variety of causes of stent thrombosis after DES implantation, coronary endothelial dysfunction manifested or exaggerated by DES implantation should not be overlooked. This review article summarizes previous reports on coronary endothelial dysfunction after DES implantation and/or coronary spasm … …Current Research in Medicine, Vol. 3, Issue 2 · 30 Apr 2012 · 7,936 accessesView PDFCite
Research ArticleOpen accessIn the abstractRole of Cardioprotective Diet in Acute Coronary SyndromeR. B. Singh, Suniti Dharwadkar, Fabien DeMeester et al.Problem statement: Nutritional factors appear to be quite important in the pathogenesis and prognosis among patients of Acute Myocardial Infarction (AMI) or Acute Coronary Syndrome (ACS). Increased consumption of proinflammatory foods; such as refined starches and sugar, trans fat, saturated fat and w-6 fatty acids may increase proinflammatory cytokines, oxidative stress and free fatty acids causing endothelial dysfunction. Approach: Columbus … …Current Research in Medicine, Vol. 2, Issue 2 · 15 Oct 2011 · 7,460 accessesView PDFCite
Research ArticleOpen accessIn the abstractHepatitis B and C Positivity in Various Categories of Human Immunodeficiency Virus Seropositive Individuals in a Regional STD Centre-an Eight-Year Evaluation of Trends and Risk FactorsSumathi Muralidhar, Manju Bala, Rakesh Kumar Jain et al.Problem statement: Among the various infections whose incidence has increased since the advent of HIV/AIDS, Hepatitis B and C stand out clearly. This is so because the routes of transmission of these infections are essentially the same as those of HIV/AIDS, making co-infections a common occurrence. The risk of infection for Hepatitis B and C is several times more than … …Current Research in Medicine, Vol. 1, Issue 2 · 31 Oct 2010 · 6,925 accessesView PDFCite
Research ArticleOpen accessIn the abstractSusceptibility of Candida Species Isolated From HIV Infected and Newborn Candidaemia Patients to Amphotericin BSaikat Basu, Debasrita Chakraborty, Satadal DasProblem statement: HIV infected and neonatal candidaemia is a serious condition where proper selection of the antifungal agent is the key factor in the prognosis of the disease. Thus in this study susceptibility of Candida species to Amphotericin B was explored in such patients. Approach: Forty different Candida isolates obtained from blood culture of such candidaemia cases were tested for … …OnLine Journal of Biological Sciences, Vol. 10, Issue 2 · 30 Jun 2010 · 7,466 accessesView PDFCite
Research ArticleOpen accessIn the abstractTotal Level of Serum Homocysteine in Males and Females with Coronary Heart Disease of Different Age GroupsFaisal I. Mohammad, Sally Awawdeh, Akram Saleh, Nabil A. BashirProblem statement: Elevated plasma total homocysteine concentration is a risk factor of cardiovascular disease. Total homocysteine level is a strong predictor of mortality in-patient with an angiographically confirmed Coronary Heart Disease (CHD), so we want to know at what age in males and females elevated homocysteine will be significantly elevated and this will help for better management and prognosis by … …American Journal of Biochemistry and Biotechnology, Vol. 6, Issue 2 · 30 Jun 2010 · 7,540 accessesView PDFCite