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75 results for “Necrosis”
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Research ArticleOpen accessIn the abstractTherapeutic Effects of Phyllanthus Species: Induction of TNF-α-mediated Apoptosis in HepG2 Hepatocellular Carcinoma CellsSripathi M. Sureban, Dharmalingam Subramaniam, Paramasivam Rajendran et al.Phyllanthus species, especially P. amarus is a medicinal plant with hepatoprotective activity, believed to occur in part by inhibiting hepatitis B virus function. The pathogenesis mechanism of viral hepatitis is closely related to hepatocyte necrosis apoptosis. The aim of our study was to investigate the in vitro effects of extracts from three Phyllanthus species, P. urinaria, P. amarus and P. … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 4 · 31 Dec 2007 · 9,005 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Action of Bovine Cartilage on Tumor Cells In Vitro And In VivoArax Tanelian, Alexander M. AbdelnoorIn an earlier study we had investigated the effect of Bovine Cartilage (BC) on mouse melanoma cells. In pursuant to this study BC anti-tumor activity in vitro against several human tumor cell lines was evaluated, mechanism by which BC induces tumor cell death was studied and its immunogenicity was assessed. Five mice received Intraperitoneal (IP) injection of BC once every … …American Journal of Immunology, Vol. 14, Issue 1 · 23 Jan 2018 · 9,664 accessesView PDFCite
Research ArticleOpen accessIn the abstractEimeria Legionensis and Eimeria kofoidi (Apicomplexa: Eimeriidae) Infection and Associated Lesions in Naturally Infected Red-Legged Partridges (Alectoris rufa)G. Fichi, G. Rossi, Stefania PerrucciWith the aim to identify the Eimeria species responsible for coccidiosis in 50 deceased red-legged partridges (Alectoris rufa), individual faecal samples were collected, dissolved in 2.5% K2Cr2O7 solution and maintained at room temperature to allow sporulation of the oocysts. Morphology and dimensions of sporulated oocysts were microscopically evaluated. To assess Eimeria intestinal localisation, faecal samples and scrapings taken from the … …American Journal of Animal and Veterinary Sciences, Vol. 12, Issue 4 · 9 Nov 2017 · 7,689 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe -863 TNF-α Polymorphism and Primary Open Angle Glaucoma in EgyptiansWalaa Bayoumie Abdulwahhab El Gazzar, Shaymaa Mohamed Abd El Rahman, Mohamed Nagy Elmohamady et al.Growing evidence indicates that TNF-alpha is involved in the pathogenesis of POAG in several ways, primarly by induction of retinal ganglion cells apoptosis and therefore optic nerve degeneration. TNF-alpha and POAG relationship has been studied at the genetic level with variable results in different populations. The transcription rate and the release of the TNF-alpha cytokine have been reported to be … …American Journal of Biochemistry and Biotechnology, Vol. 13, Issue 2 · 1 Jun 2017 · 7,356 accessesView PDFCite
EditorialOpen accessIn the abstractIs Rerum® the New Coley's Vaccine?Marco RuggieroColey's Vaccine and Cancer Immunotherapy Dr. William B. Coley is credited for having been the first to translate the observation of an association between bacterial infections, high fever and cancer remission into a successful cancer treatment. However, it is worth noting that such an association dates back to at least one century before Coley's times; as Wiemann and Starnes from … …American Journal of Immunology, Vol. 13, Issue 2 · 31 May 2017 · 12,281 accessesView PDFCite
Research ArticleOpen accessIn the abstractBurn Wound Healing Effect and Hair Growth Promoting Activity of Lawsonia inermis L. and Honey in Oryctolagus cuniculus RabbitsZouhir Djerrou, Imane Mokhbi, Khadidja Saci Hadef et al.This study aimed to assess Lawsonia inermis L. and honey mixture effects on burn wounds and hair growth in rabbits. Nine male Oryctolagus cuniculus local rabbits were allocated randomly in 3 groups. After antisepsis and local anesthesia, four circular burns were created on the animal’s backs. Immediately after burning, the wounds were covered with honey in three rabbits (HON group), … …OnLine Journal of Biological Sciences, Vol. 16, Issue 2 · 23 Apr 2016 · 7,812 accessesView PDFCite
Review ArticleOpen accessIn the abstractRole of Cytokines and Transcription Factors in Periodontitis: A Review of Cellular and Molecular MechanismsAnne Carolina Eleutério Leite, Valéria Martins de Araújo Carneiro, Júlia Faria Nunes et al.Periodontal Diseases (PD) are characterized by pathological manifestation of host immune response to bacterial infection at the tooth/gingival interface. Evidences points periodontitis as a risk factor for pathological systemic conditions, such as, cardiovascular diseases and diabetes. The identification of host factors that determine their susceptibility to immune subversion can provide useful information in the pathogenesis of periodontitis. Protective acute inflammatory … …American Journal of Immunology, Vol. 11, Issue 4 · 9 Dec 2015 · 7,807 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of Serum Interleukin-8 (CXCL8) Concentrations in Tumor Bearing DogsMelanie Haas, Franz-Josef Kaup, Stephan NeumannInterleukin-8 (IL-8 or CXCL8) is a pro-inflammatory and angiogenic chemokine involved in tumorigenesis. Serum CXCL8 is elevated in various neoplastic diseases, but its potential value as a tumor marker in veterinary medicine is unknown. Here, we measured serum CXCL8 concentrations in dogs with various neoplastic diseases using a commercially available canine ELISA kit and analyzed its relationship with patient and … …American Journal of Animal and Veterinary Sciences, Vol. 10, Issue 4 · 24 Nov 2015 · 6,975 accessesView PDFCite
Research ArticleOpen accessIn the abstractHippocampal Pyramidal Cell Degeneration and Changes in Creb Protein in Datura stramonium Treated RatsPeter Etim Ekanem, Dare S. Sunday, Sunday Abba, Amanuel TesfayDatura Stramonium (DS) is a tropical shrub which is available worldwide. It has various uses and is often used to increase the intoxication of certain beverages. The seeds of this plant are very toxic but are commonly smoked in like manner as tobacco. The present study investigated the potential harmful effects of DS on pyramidal cells and CREB protein in … …Neuroscience International, Vol. 6, Issue 2 · 17 Sep 2015 · 7,062 accessesView PDFCite
Research ArticleOpen accessIn the abstractFactors Those Up Regulate Klotho and Glutathione Peroxidase-1 Gene Expression Improve Renal Function in Rats with Acute Renal FailureFatma E. El-Gendey, Shabaan A. Hemeda, Gamal A. Sosa, Naglaa F. AlhusseiniAcute Renal Failure (ARF) has traditionally been defined as the abrupt and progressive loss of kidney functions resulting in the retention of urea and other nitrogenous waste products associated with interstitial inflammation, tubular injury and increasing Tumor Necrosis Factor (TNF). Mortality in patients with ARF remains high >50% in severely ill patients. Klotho gene is a new anti-aging gene. Genetic … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 3 · 15 Aug 2015 · 7,097 accessesView PDFCite