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Research ArticleOpen accessEvery word in the titleAn Integrated Machine Learning Model for Heart Disease Classification and CategorizationSrikanth Meda, Raveendrababu BhogapathiProgressions in the coordination among the machine learning algorithms, helped to achieve high accuracy and reliability in decision-making systems. Due to the impact and importance of heart diseases in real life, designing the efficient heart disease prediction model become a pivotal aspect today. Former research scholars applied the popular supervised machine learning models like Decision Trees, Naïve Bayes, ANN's, and … …Journal of Computer Science, Vol. 18, Issue 4 · 19 Apr 2022 · 6,539 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleDiagnosing Alzheimer’s Disease using Convolution Neural NetworksSarita, Saurabh Mukherjee, Tanupriya Choudhury et al.Alzheimer’s is a disease wherein constant degeneration of neurons and their synapses result in impaired brain functioning which leads to personality changes, memory loss, thinking and speech disorder. So, there is a requirement of an automated and early diagnosis of this disease to decrease the death rate. The proposed work is coupled with deep learning techniques to predict the Alzheimer’s … …Journal of Computer Science, Vol. 18, Issue 2 · 21 Feb 2022 · 7,350 accessesView PDFCite
Literature ReviewOpen accessEvery word in the titleAtherosclerosis as Age-Related Disease: The Potential of Sirtuins TreatmentAnastasia Vladimirovna Poznyak, Victor Yurievich Glanz, Vasily Nikolaevich Sukhorukov et al.Atherosclerosis, a global health concern, has attracted researchers worldwide due to its severe consequences. The elderly are particularly susceptible to cardiovascular diseases and events, making them a high-risk group. Although gaps in our understanding of atherosclerosis pathogenesis persist, it is evident that oxidative stress, endothelial dysfunction, inflammation, mitochondrial dysfunction, and autophagy impairments are key components of its development. Remarkably, these … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 16 May 2024 · 4,718 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAnalysis of Plasma Amyloid-Beta and Apolipoprotein E Genotypes as Markers of Alzheimer’s Disease in Healthy Korean AdultsEun Ju Oh, Jung Jae Lee, Bo Kyeung Jung, Jae Kyung KimThe presence of the ApoE4 allele interferes with human Amyloid-Beta (Aβ) clearance and reduces the neuronal damage response, which, in turn, is associated with increased Alzheimer’s Disease (AD) risk. Identifying individuals with the highest genetic risk may aid clinical AD diagnosis and prognosis. However, to the best of our knowledge, no previous study has performed blood-based analysis of ApoE polymorphisms … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 1 · 26 Mar 2024 · 4,495 accessesView PDFCite
Case ReportOpen accessEvery word in the titleA Unique Presentation of Creutzfeldt-Jakob Disease in a Patient Consuming Deer Antler VelvetJoseph Wiedemer, Yanely Sanchez Ceja, An Cao, Ibrahim MustafaCreutzfeldt-Jakob Disease (CJD) is a rare rapidly progressive neurodegenerative prion disorder that is usually sporadic but may also be acquired from exposure to infected sources, classically via infections of bovine or human etiology. Cervid transmission of CJD is of particular concern in North America given the rapid spread of Chronic Wasting Disease (CWD)- the Cervid version of CJD. We present … …American Journal of Infectious Diseases, Vol. 17, Issue 1 · 18 Mar 2021 · 7,560 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleKRLSMDA: Identifying Human miRNA–Disease Association Based on Similarity and Kronecker Regularized Least Squares MethodLingzhi Zhu, Weimin Gao, Guixiang Li et al.A growing number of studies have suggested that miRNAs (microRNAs) have associations with human diseases, the design and discovery of drug. But so far, we do not yet fully understand the molecular mechanism of miRNAs in the development of human diseases. Predicting miRNA-disease associations is helpful for understanding the molecular mechanism of miRNAs in the development of human diseases. However, … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 1 · 15 Mar 2021 · 6,408 accessesView PDFCite
Review ArticleOpen accessEvery word in the titleBioactive Functional Foods for Cardiovascular DiseasesKiren Mustafa, Iqra Ajmal, Tahira Naz et al.Cardiovascular Disease (CVD) is a chronic pathological disorder regarded as a serious health concern round the globe. It is a multifactorial disease, with a range of various causative agents, among that dietary factor is considered the most important and may to a large degree determine CVD risk. Unfortunately, it has been less widely investigated. This review outlines the general aspects … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 3 · 17 Aug 2020 · 7,842 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleStudy and Analysis of Prediction Model for Heart Disease Data Using Machine Learning TechniquesB. Santhi, K. RenukaHeart disease is the number one cause of death for all communities of individuals in advanced countries and a major problem for emerging nations too. Doctors’ availability to care for the general population could not catch up with the present demand for healthcare. So, there is a severe need for a support system to assist save individuals. With novel ML … …Journal of Computer Science, Vol. 16, Issue 3 · 26 Mar 2020 · 7,794 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAn Analysis of Heart Disease for Diabetic Patients Using Recursive Feature Elimination with Random ForestBindushree Doddasiddavanahalli Channabasavaraju, Udayarani VinayakamurthyData Mining Techniques are used in many areas like banking, healthcare, education because of extracting relevant information from the database. Many algorithms in data mining are used to predict the disease to reduce the patient treatment cost as well as increase the diagnosis accuracy. In this research work, the risk level of diabetic heart disease patient can be predicted using … …Journal of Computer Science, Vol. 16, Issue 1 · 27 Jan 2020 · 7,936 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleClinical Analysis of Pulmonary Mycobacterium kansasii DiseaseYoshihiro Kobashi, Masaaki Abe, Daisuke Yoshioka et al.To investigate the clinical aspects of pulmonary Mycobacterium kansasii (M. kansasii) disease. In 25 patients who satisfied the diagnostic criteria of the American Thoracic Society, we retrospectively evaluated the background, diagnostic methods, laboratory findings, radiological findings, treatment and prognosis. The median age was 61 years old (20 males, 5 females). Nine patients (36%) had no underlying diseases. The definite diagnosis … …American Journal of Infectious Diseases, Vol. 16, Issue 1 · 21 Jan 2020 · 7,115 accessesView PDFCite