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57 articles for “Cytotoxicity”
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Research ArticleOpen accessIn the abstractCytotoxic Activity of Tinospora crispa Crude Extracts (Stem) Against K562 Human Leukemia CellsNormah Awang, Haziratul Iffah Ruzali, Rapidah Mohamad et al.Tinospora crispa (T. crispa) is traditionally used as an herbal medicine for treatment of gout and is an analgesic, anti-inflammatory and antihyperuricemic agent. Cytotoxicity of hexane, dichloromethane, ethanol and aqueous extracts of T. crispa stem against K562 cells was assessed. Crude extracts of T. crispa stem were obtained by sonication and maceration methods. T. crispa stem powder was macerated and … …OnLine Journal of Biological Sciences, Vol. 19, Issue 2 · 11 May 2019 · 7,870 accessesView PDFCite
Literature ReviewOpen accessIn the abstractFundamental Questions about γδT CellsMoulay Yassine Belghali, Saadia Ba-M’hamed, Mouna Khouchani, Brahim AdmouγδT cells is a minor subgroup of T lymphocytes expressing γδ-T Cell Receptor (TCR), with many subsets, dominated by Vδ2 and Vδ1. γδT cells recognize antigens independently of the context of MHC class I, MHC class II, or CD1 presenting molecules. However, this recognition requires the expression of the transmembrane Butyrophilin proteins by the presenting cells. Their activation is controlled … …OnLine Journal of Biological Sciences, Vol. 20, Issue 4 · 15 Dec 2020 · 6,382 accessesView PDFCite
Research ArticleOpen accessIn the abstractIn Vitro Biological Profiles and Chemical Contents of Ethanolic Nest Entrance Extracts of Thai Stingless Bees Tetrigona apicalisTouchkanin Jongjitvimol, Sathirapong Kraikongjit, Pussadee Paensuwan, Jirapas JongjitwimolTetrigona apicalis is a species of stingless bees found in Lower Northern Thailand. They normally construct their nest entrances as an external structure for protecting themselves from enemies. Their biological properties have not well characterized yet. The objectives of this study were to evaluate the antibacterial, antifungal and anti-proliferative activities of their nest entrances. Samples were collected from four provinces … …OnLine Journal of Biological Sciences, Vol. 20, Issue 3 · 2 Nov 2020 · 6,781 accessesView PDFCite
Research ArticleOpen accessIn the abstractHousing Pregnant Sows in Turnaround Stalls During Gestation Impacts Behavior, Immune and Well-BeingAshley DeDecker, Michael Mandru, Janeen L. Salak-JohnsonThis study aimed to determine the effects of housing gestating multiparous sows in alternative turn-around stalls on selective measures of well-being. Sows were randomly assigned to either a Turn-Around Stall (TAS) or standard Straight Stall (STS) from gestational day 6 until 110. Behavior was registered on days 6, 30, 45, 65, 90 and 110 of gestation and immune and cortisol … …American Journal of Animal and Veterinary Sciences, Vol. 13, Issue 4 · 14 Nov 2018 · 7,965 accessesView PDFCite
Research ArticleOpen accessIn the abstractSynthesis, Characterization and Biological Activities of Organotin (IV) Methylcyclohexyldithiocarbamate CompoundsNormah Awang, Ibrahim Baba, Bohari M. Yamin et al.Problem statement: The growing interest in the chemistry of sulphur donor ligands are due to their encouraging anticancer, antibacterial and antifungal activities as well as their widespread industrial application. Dithiocarbamates belong to this class and much attention has been paid to them. Approach: Novel organotin compounds with the molecular formula RmSn[S2CN(CH3)(C6H11)]4-m (where m = 2, R = CH3, C2H5; m … …American Journal of Applied Sciences, Vol. 8, Issue 4 · 18 Apr 2011 · 9,210 accessesView PDFCite
Research ArticleOpen accessIn the abstractCytotoxic and Antimicrobial Potential of Actinomycete Species Saccharopolyspora salina VITSDK4 Isolated from the Bay of Bengal Coast of IndiaK. Suthindhiran, K. KannabiranProblem statement: Although the diversity of marine Actinobacteria have been studied and biotechnologically exploited throughout the world, the studies on marine actinobacteria in Indian peninsula are largely unexplored. Of 9 maritime states in India, only 4 states have been extensively studied for the diversity of actinobacteria. Further, the studies on bioactive actinomycetes from saline soil are very scanty. In the … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 11,440 accessesView PDFCite
Research ArticleOpen accessIn the abstractChronic Mental Stress Induces Reversible Reduction of Natural Killer Cells and CD56dim SubpopulationManar M. IsmailGenerally, studying to be a health care provider is a stressful and demanding field and the students have to face many stressors that may affect their general health status including the immune system. This work aimed at studying the effect of prolonged naturalistic life-stress exposure on the percentage of peripheral blood T-lymphocytes and Natural Killer (NK) cells in female laboratory … …American Journal of Immunology, Vol. 13, Issue 3 · 30 Aug 2017 · 7,792 accessesView PDFCite
Research ArticleOpen accessIn the abstractBiocompatibility of Orthodontic Resins: In vitro Evaluation of Monomer Leaching and Cytotoxic EffectsRoberto Uomo, Gianrico Spagnuolo, Giuseppina Nocca et al.The aim of this study was to investigate the effect of orthodontic resins on cell survival and to evaluate monomer leaching both before and after resin polymerization. Materials and methods: 3T3 mouse fibroblasts were exposed to three cured and uncured orthodontic resins. Cellular viability was assessed by Alamar Blue assay after 24, 48 and 72 h. High Performance Liquid Chromatography … …Current Research in Dentistry, Vol. 8, Issue 1 · 7 Jul 2017 · 16,333 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnticancer Activity of Isolated Chemical Constituents from Miliusa smithiaeChonthicha Naphong, Wilart Pompimon, Punchavee SombutsiriMiliusa plants belonging to the family Annonaceae are found in Thailand and have been used as Thai traditional medicines. There have been a few previously reports on the chemical constituents of plants in this genus, describing the presence of aporphine alkaloids, terpenoids, flavonoids, phenylpropanoids, styrylpyrones, bis-styryls and homogentisic acid derivatives. Miliusa smithiae, a new species for Thailand and world, has … …American Journal of Applied Sciences, Vol. 10, Issue 8 · 24 Jul 2013 · 7,259 accessesView PDFCite
Research ArticleOpen accessIn the abstractBio-Guided Study on Melastoma malabathricum Linn Leaves and Elucidation of its Biological ActivitiesMourouge Saadi Alwash, Nazlina Ibrahim, Wan Yaacob AhmadThe present study aimed to isolate and identify constituents with antibacterial activity from the Methanol extract of Melastoma malabathricum leaves (MMML) through bioassay guided fractionation. Furthermore, the study scoped to evaluate the cytotoxic effects of M. malabathricum leaves fractions for possible protective effect of antoxidative constituents present in the fractions. The MMML extract was fractionated by Vacuum Liquid Chromatography (VLC) … …American Journal of Applied Sciences, Vol. 10, Issue 8 · 24 Jul 2013 · 9,513 accessesView PDFCite