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154 results for “Cancer Cell”
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Research ArticleOpen accessIn the abstractCPF-Net: Cross-modal CT and Pathology Guided Feature Learning for CT-based Lung Cancer Subtype ClassificationPeizhi Tan, Debiao YanAccurate classification of lung cancer subtypes from CT images remains challenging due to the subtle radiological differences between adenocarcinoma (LUAD) and squamous cell carcinoma (LUSC). We propose CPF-Net, a deep learning framework that integrates CT and pathological information through a Linear Spatial Reduction Attention (LSRA) module. The framework processes whole slide images using a modified CTransPath architecture for pathological feature … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 3 · 23 Jan 2026 · 1,856 accessesView PDFCite
Review ArticleOpen accessIn the abstractUnveiling Skin Cancer: A Review of Deep Learning Techniques for DetectionGoutham Lal Shanmughamadom Harilal, Tamilselvi PanneerselvamEarly identification is essential for successful treatment and better patient outcomes since skin cancer is caused by damage to DNA in skin cells, which can result in genetic abnormalities and the possibility of metastasis. The present systematic review scrutinizes the efficacy and obstacles of early detection techniques, which differentiate between benign and malignant lesions by examining lesion attributes such as … …Journal of Computer Science, Vol. 21, Issue 9 · 23 Oct 2025 · 2,602 accessesView PDFCite
Research ArticleOpen accessIn the abstractCytotoxicity and Apoptosis Prevailed by Tricyclohexyltin(IV) Dithiocarbamate Compounds Against Human Lung Carcinoma Cell Line (A549)Normah Awang, Nurul Amalina Abd Aziz, Nur Fatini Nordin, Nurul Farahana KamaludinIn Malaysia, lung cancer is a highly common kind of cancer and the leading cause of cancer-related deaths. This study examined the cytotoxicity of two new tricyclohexyltin(IV) dithiocarbamate compounds compounds, which are tricyclohexyltin(IV) N-methyl-N-benzyldithiocarbamate (C1) and tricyclohexyltin(IV) N-ethyl-N-benzyldithiocarbamate (C2), on lung carcinoma cell lines (A549) of humans. The cytotoxicity was assessed using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT) assay. Cell death mode … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 13 Jun 2024 · 4,622 accessesView PDFCite
Review ArticleOpen accessIn the abstractThe Impact of Di-2-Ethylhexyl Phthalate (DEHP) in Focus on the Reproductive System and Toxicity in Rat or Mammalian ModelVenkataramanaiah Poli, Srinivasulu Reddy MotireddyAbsalan, F., Saremy, S., Mansouri, E., Moghadam, M. T., Moghadam, A. R. E., & Razie, G. (2016). Effects of Mono-(2-Ethylhexyl) Phthalate and Di-(2-Ethylhexyl) Phthalate Administrations on Oocyte Meiotic Maturation, Apoptosis and Gene Quantification in Mouse Model. Cell Journal, 18(4), 503–513. https://doi.org/10.22074/cellj.2016.4717 Acevedo‐Rodriguez, A., Kauffman, A. S., Cherrington, B. D., Borges, C. S., Roepke, T. A., & Laconi, M. (2018). Emerging … …American Journal of Pharmacology and Toxicology, Vol. 19, Issue 1 · 6 Jun 2024 · 12,990 accessesView PDFCite
Research ArticleOpen accessIn the abstractCross Talk between Iron Regulatory Proteins and Proinflammatory Molecules in Ovarian Cancer Patients Based on Menopausal StatusHaritha Padannapurath Manoj, Sudha Kuthethur, Reshma Kumarchandra et al.Micronutrient iron is postulated to contribute to the initiation of cancer mainly by the formation of Reactive Oxygen Species (ROS), the key signaling molecules of inflammatory reactions. Iron may also cause elevation of MMP9, a gelatinase responsible for remodeling extracellular matrix in cancer cells through the ROS pathway. Estrogen the hormone which decreases markedly in post menopause is also known … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 31 May 2024 · 4,491 accessesView PDFCite
Research ArticleOpen accessIn the abstractMechanism Analysis of Artemisinin and Artesunate as Lung Cancer Therapy Agents Through in Silico MethodDidik Harmoko, Vivitri Dewi Prasasty, Adi YulandiSeveral in vitro studies have focused on the ability of artemisinin and its derivatives to suppress lung cancer cells, but there are still many biological processes and mechanisms, such as the interactions between the active compounds (ligands) and receptors that are not well understood and require further research. Drug targeting for lung cancer will be more precise and the inhibition … …OnLine Journal of Biological Sciences, Vol. 24, Issue 3 · 15 Feb 2024 · 6,144 accessesView PDFCite
Research ArticleOpen accessIn the abstractRadial Basis Function Networks and Contrast-Limited Adaptive Histogram Equalization Filter Based Early-Stage Breast Cancer Detection TechniquesAnitha Ponraj, Aroul CanessaneBreast cancer is one of the most common types of cancer that kills women. When cells become uncontrollably large, cancer develops. As a result, detecting and classifying breast cancer in its early stages is essential so that patients can take the appropriate precautions. On the other hand, mammography images have relatively low sensitivity and effectiveness in detecting breast cancer. Furthermore, … …Journal of Computer Science, Vol. 19, Issue 6 · 25 May 2023 · 5,613 accessesView PDFCite
Research ArticleOpen accessIn the abstractUse of Novel Triphenyltin (IV) Dithiocarbamate Compounds in Assessing the Cytotoxicity and Mode of Cell Death of Acute Lymphoblastic Leukemia Cell Lines, CCRF CEM (CCL-119)Normah Awang, Nur Hidayah Hasrin, Nurul Farahana Kamaludin et al.Chemotherapy and radiotherapy are often used to treat Acute Lymphoblastic Leukemia (ALL). However, the resistance problem of treatment using the current drug in ALL patients has decreased the effectiveness of such therapy. Therefore, a study needs to be conducted to identify the potential of new anticancer agents. Organotin (IV) dithiocarbamate, an organometallic compound, causes toxic effects on cancer cells in … …OnLine Journal of Biological Sciences, Vol. 23, Issue 2 · 10 Mar 2023 · 5,159 accessesView PDFCite
Research ArticleOpen accessIn the abstractEarly Responses of Neural Cells (U87) to Particulate Matter Exposure: Cell Viability and Cytokine ConcentrationJae-Sik Jeon, Eun Ju Oh, Qian-Wen Wang, Jae Kyung KimParticulate Matter (PM) has a significant impact on human health and increases the risk of respiratory diseases. PM exposure is linked to various illnesses, including cardiovascular diseases, cancer, neurological diseases, and pregnancy complications, and contributes to both mortality and morbidity globally. PM can also influence the autonomic nervous system. The evidence suggests that the likelihood of developing lung cancer continually … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 1 · 20 Feb 2023 · 5,450 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Comprehensive Review on Skin Cancer Detection Strategies using Deep Neural NetworksAkepati Sankar Reddy, Gopinath M. PSkincancer is a deadly malignancy. Incomplete D.N.A. repair in skin cells causeshereditary mutations and cancer. Early skin cancer is easier to treat since itspreads slowly to other body areas. As a result, the optimal time to find it isduring its infancy. Because of the rising frequency of skin cancer, the highmortality rate, and the high cost of medical treatment, early … …Journal of Computer Science, Vol. 18, Issue 10 · 5 Oct 2022 · 6,400 accessesView PDFCite