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86 results for “Breast Cancer”

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Research ArticleOpen accessIn the keywordsMammogram Analysis Based on Pixel Intensity Mean FeaturesR. Nithya, B. SanthiProblem statement: In the recent years, Computer Aided Diagnosis (CAD) can be very useful for detection of breast cancer. Mammography can be used as an efficient tool for breast cancer diagnosis. A computer based diagnosis and classification system can reduce unnecessary biopsy. Approach: This study investigates a new approach to the classification of mammogram images based on pixel intensity mean … …Journal of Computer Science, Vol. 8, Issue 3 · 7 Jan 2012 · 7,670 accessesView PDFCite
Research ArticleOpen accessIn the keywordsPredicting the Severity of Breast Masses with Ensemble of Bayesian ClassifiersAlaa M. ElsayadProblem statement: This study evaluated two different Bayesian classifiers; tree augmented Naive Bayes and Markov blanket estimation networks in order to build an ensemble model for prediction the severity of breast masses. The objective of the proposed algorithm was to help physicians in their decisions to perform a breast biopsy on a suspicious lesion seen in a mammogram image or … …Journal of Computer Science, Vol. 6, Issue 5 · 31 May 2010 · 7,306 accessesView PDFCite
Research ArticleOpen accessIn the keywordsTamoxifen Drug Loading Solid Lipid Nanoparticles Prepared by Hot High Pressure Homogenization TechniquesNagi A. ALHaj, Rasedee Abdullah, Siddig Ibrahim, Ahmad BustamamAs drug delivery systems Nanoparticulate widely investigated because of many advantages such as smaller size, controlled drug release potential, targeting ability, enhancement of therapeutic efficacy and reduction of toxicity. So, Solid Lipid Nanoparticles have recently received considerable attention as alternative drug delivery carrier. In this study Solid Lipid Nanoparticles (SLNs) containing tamoxifen, nonsteroidal antiestrogens have been loaded and to be … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 3 · 30 Sep 2008 · 15,176 accessesView PDFCite
Research ArticleOpen accessIn the keywordsInternalizing Versus Non-internalizing Receptors for Targeting L-Methioninase to Cancer CellsXiao-Ping Zang, Naveen R. Palwai, J. T. Pento, Roger G. HarrisonWe reported previously that L-methioninase targeted to the urokinase receptor of MCF-7 breast cancer cells is significantly more effective in inhibiting cell proliferation and migration than free L-methioninase both in vitro and in vivo. L-methioninase was targeted by linking at its amino terminus to an amino-terminal fragment (ATF) of urokinase. The ATF was selected for targeting because is has previously … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 3 · 30 Sep 2006 · 7,818 accessesView PDFCite
Research ArticleOpen accessIn the keywordsRisk of Second Non Breast Malignancies (SNBM) in Relation to Brca1 And Brca2 Mutation Status Following Breast-Conserving Surgery and RadiotherapyYoulia M. Kirova, Alain Fourquet, Alexia Savignoni, Brigitte Sigal-ZafraniWomen from hereditary breast cancer families with BRCA1/2 germline mutation are at increased risk for contralateral breast cancer (BC) and for ovarian cancer (OC). It is less clear whether mutation status influences the rate of SNBM other than OC. In addition, little is known on the risk of OC in individuals from hereditary BC families without identified BRCA mutation. Our … …American Journal of Immunology, Vol. 2, Issue 3 · 30 Sep 2006 · 7,230 accessesView PDFCite
Review ArticleOpen accessIn the keywordsBrief Overview of Specific Features of Cancer in Atherosclerosis Patients and Therapeutic StrategiesAnastasia Vladimirovna Poznyak, Varvara Alexandrovna Orekhova, Vasily Nikolaevich Sukhorukov et al.Cardiovascular Conditions (CVD) as well as cancer are the main death causes globally. Characteristically, there are numerous interrelations and intersections between these two groups of diseases. So, in particular, cardiovascular disease is one of the main comorbidities and death causes in cancer patients. The development of atherosclerosis is promoted by aggressive anticancer therapy regimens and various risk factors, including hypertension, … …OnLine Journal of Biological Sciences, Vol. 23, Issue 4 · 22 Sep 2023 · 4,526 accessesView PDFCite
Research ArticleOpen accessIn the keywordsClassification of Breast Tumor in Mammogram Images Using Unsupervised Feature LearningAidarus M. Ibrahim, Baharum Baharudin, Abas Md Said, P. N. HashimahIn this study, we propose a learning-based approach using feature learning to minimize the manual effort required to extract features. Firstly, we extracted features from equally spaced sub-patches covering the input Region of Interest (ROI). The dimensionality of the extracted features is reduced using max-pooling. Furthermore, spherical k-means clustering coupled with max pooling (k-means-max pooling) is compared with well-known feature … …American Journal of Applied Sciences, Vol. 13, Issue 5 · 13 May 2016 · 7,503 accessesView PDFCite
Research ArticleOpen accessIn the keywordsIdiopathic Granulomatous Mastitis: A Case ReportMojtaba Varshochi, Mehdi Haghdoost, Omid MashrabiProblem statement: Granulomatous Lobular Mastitis (GLM) or autoimmune mastitis is a rare and benign disease which, except one case reported in an old man, is usually seen during pregnancy or lactation period. This disease was described for the first time by Kessler. Approach: Our case is a 34 year-old woman who has a child with a history of using OCP … …American Journal of Infectious Diseases, Vol. 6, Issue 3 · 30 Sep 2010 · 8,743 accessesView PDFCite
Research ArticleOpen accessIn the keywordsHER2 Protein Overexpression in Infiltrating Ductal Carcinoma of the Breast Associated with Lymph Node InvolvementAdrienne Pratti Lucarelli, Maria Marta Martins, Vilmar Marques Oliveira et al.The current study compares the rates of overexpression of the HER2 protein in stage II ductal carcinoma of breast in patients with lymph-node involvement. The research material was tissue sections obtained from the primary tumor of 28 patients with lymph-node involvement. The technique used to detect the protein was immunohistochemistry. The overexpression of HER2 protein occurred in 33.3% of lymph … …American Journal of Applied Sciences, Vol. 6, Issue 3 · 31 Mar 2009 · 7,126 accessesView PDFCite
Research ArticleOpen accessIn the keywordsA BI-RADS Based Expert Systems for the Diagnoses of Breast DiseasesUmi Kalthum Ngah, Shalihatun Azlin Aziz, Mohd. Ezane Aziz et al.We proposed an expert system based on the interpretation of mammographic and ultrasound images that may be used by expert and non-expert doctors in the interpretation and classifying of patient cases. The expert system software consists of a mammographic (MAMMEX) and breast ultrasound (SOUNDEX) medical expert systems which may be used to deduce cases according to the Breast Imaging Recording … …American Journal of Applied Sciences, Vol. 4, Issue 11 · 30 Nov 2007 · 7,434 accessesView PDFCite