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101 articles for “Animal model”
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Review ArticleOpen accessIn the abstractCirculating Immune Complexes as an Important Link between Inflammation and Lipid Alterations in AtherosclerosisAnastasia Vladimirovna Poznyak, Nikolay Alexandrovich Orekhov, Vasily Nikolaevich Sukhorukov et al.This review article rigorously investigates the emerging facets of atherosclerosis pathogenesis through an exhaustive examination of the existing data on the intricate interplay between lipid metabolism disorders and inflammation. A primary objective of this study is to thoroughly explore the role of Circulating Immune Complexes (CIC) as a pivotal indicator of this multifaceted interaction. The focus of this review centers … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 14 Aug 2024 · 3,932 accessesView PDFCite
Review ArticleOpen accessIn the abstractPotential Effects of Adropin in Subarachnoid HemorrhageZahra Hasanpour Segherlou, Mohammad Reza Hosseini Siyanaki, Brandon Lucke-WoldSubarachnoid Hemorrhage (SAH) typically, occurs in patients over 55 years of age and can cause a significant loss of productivity. SAH also has a high mortality rate and those who survive often suffer from early and secondary brain injuries that can result from the condition. By gaining a better understanding of the pathophysiology of SAH, it may be possible to … …Neuroscience International, Vol. 13, Issue 1 · 21 Jul 2023 · 9,246 accessesView PDFCite
Research ArticleOpen accessIn the abstractAlterations in Interleukin-1β and Interleukin-6 in Mice Inoculated Through the Oral Routes Using Graded Doses of p. Multocida Type b: 2 and its LipopolysaccharideOmar Suwaidan Ali, Lawan Adamu, Faez Firdaus Jesse Abdullah et al.The gram-negative bacterium Pasteurella multocida serotype B: 2 is an important veterinary and opportunistic human pathogen that causes deplorable welfare problems and colossal economic production losses in bovine and other animal species throughout the world. Pasteurella multocida type B: 2 and its LPS are associated with Haemorrhagic Septicaemia (HS) in mice as animal model. Sixty healthy Balb c mice were … …American Journal of Animal and Veterinary Sciences, Vol. 10, Issue 1 · 22 Dec 2014 · 7,696 accessesView PDFCite
Research ArticleOpen accessIn the abstractTHE USAGE OF ANIMAL AND VEGETABLE ORIGIN RAW MATERIALS COMBINATORICS IN MEAT PRODUCTS OF &#34HALAL&#34 CATEGORY DEVELOPMENTIvan F. Gorlov, Oksana B. Gelunova, Tatiana M. Giro, Ekaterina P. MirzayanovaIntegrated researches aimed to develop technologies and recipes for meat products of &#34Halal&#34 category using seed fat and Milk Protein-Carbohydrate Concentrate (MPCC) represent a new generation of scientific and practical interest. In this connection, the authors propose technologies and recipes for meat products of &#34Halal&#34 category, designed on the basis of rational combinatorics of animal and vegetable origin raw materials, … …American Journal of Agricultural and Biological Sciences, Vol. 9, Issue 4 · 15 Oct 2014 · 7,654 accessesView PDFCite
EditorialOpen accessIn the abstractGLUTATHIONE: A POSSIBLE LINK TO AUTOPHAGY IN SYSTEMIC LUPUS ERYTHEMATOSUSDilip Shah, Swapan K. NathIncreased free radical formation and altered redox state are of fundamental importance in the pathogenesis of autoimmune diseases including Systemic Lupus Erythematos (SLE). Free radicals are mainly derived from oxygen (Reactive Oxygen Species/ROS) and nitrogen (Reactive Nitrogen Species/RNS) at mitochondria, cellular membranes and the endoplasmic reticulum membrane as physiological responses to a variety of internal and external stress (Shah et … …American Journal of Immunology, Vol. 10, Issue 3 · 3 Sep 2014 · 12,777 accessesView PDFCite
Research ArticleOpen accessIn the abstractEFFECT OF PIOGLITAZONE ON HEPATIC ULTRA-STRUCTURE AND METABOLIC CHANGES INDUCED BY A HIGH SUCROSE DIET IN RATSMohamed D. Morsy, Ahmed S. Khashaba, Ahmed I. Agamy, Refaat A. EidPioglitazone (Pio) is a PPAR-γ agonist insulin sensitizer has anti-inflammatory activity. Our novel aspect was to investigate its hepatic anti-inflammatory activity at the level of ultra-structure and enzymatic changes in a high sucrose diet animal model. Forty male Sprague Dawley rats were divided into four equal groups: Control; control Pio; high sucrose diet; high sucrose diet Pio treated groups. Fourteen … …American Journal of Applied Sciences, Vol. 11, Issue 7 · 23 Apr 2014 · 6,735 accessesView PDFCite
Research ArticleOpen accessIn the abstractIN VIVO ANTIPLASMODIAL ACTIVITY AND ACUTE TOXICITY OF STANDARDIZED EXTRACT OF EURYCOMA LONGIFOLIA JACK. ROOT TRADITIONALLY USED TO TREAT MALARIAEti Nurwening Sholikhah, Mahardika Agus Wijayanti, MustofaA series of studies has been conducted to prove the Eurycoma longifolia Jack. root as an antimalarial. However, the in vivo antiplasmodial activity of E. longifolia Jack. root standardized extract and its lethal dose 50% (LD50) values is unknown. In vivo antiplasmodial activity was conducted on Plasmodium berghei infected Swiss mice as malaria model with 4-day suppression methods. Sixty mice … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 1 · 27 Dec 2013 · 7,736 accessesView PDFCite
Research ArticleOpen accessIn the abstractγAminobutyrate B Receptors in Central Amygdaloid and Medial Amygdaloid Nuclei of Amygdala Modulate Aggression in Male RatsMahnaz Taherianfard, Zahed Abdolahi, Hamid Rajaian et al.One neurochemical system most consistently linked with aggression is the GABAergic system. The aim of the present investigation was to examine the effect of injection of baclofen (GABAB agonist) and CGP35348 (GABAB antagonist) in the Central Amygdaloid (CA) and Medial Amygdaloid (MA) nuclei of the amygdala on offensive aggression behavior in the animal model. Sixty six adult male rats weighing … …Neuroscience International, Vol. 3, Issue 1 · 3 Sep 2012 · 7,261 accessesView PDFCite
Research ArticleOpen accessIn the abstractNeuroprotective Effect against Alzheimer's Disease of Porcine Brain ExtractWipawee Thukham-Mee, Jintanaporn Wattanathorn, Supaporn Muchimapura, Chuleratana BunchonglikitkulProblem statement: Despite the increasing importance of Alzheimer’s disease, no effective therapeutic strategy is available. Therefore, neuroprotective strategy is still required. Recent findings show that numerous substances possessing antioxidant can improve neurodegeneration and memory impairment. Based on the antioxidant effect and its reputation to serve as brain tonic in traditional folklore, we hypothesized that porcine brain extract could mitigate neurodegeneration … …American Journal of Applied Sciences, Vol. 9, Issue 5 · 5 Mar 2012 · 8,247 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntibiotic Susceptibility and Immunomodulatory Potential of Chosen Bacterial PathogensM. Sujatha, P. Dhasarathan, B. KarthickProblem statement: Antibiotic susceptibility is still the best way for bacterial pathogen escape mechanism against immunity. Approach: In the present investigation, bacterial pathogens like Staphylococcus aureus, Escherichia coli, Aeromonas hydrophila, Klebsiella and Pseudomonas aeruginosa were used to screen antibiotic susceptibility and immunomodulatory potential. Results: All the test pathogens were sensitive to all the test antibiotics 11±2 mm) except penicillin. The … …American Journal of Immunology, Vol. 6, Issue 2 · 30 Jun 2010 · 7,831 accessesView PDFCite