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177 articles for “Activation”
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Research ArticleOpen accessIn the abstractDecoding Lung Cancer: PLAU as a Critical Driver and Diagnostic MarkerStanley Cho, Min Gyeong KimLung cancer remains a leading cause of cancer-related mortality, and understanding its underlying molecular mechanisms is critical for developing targeted therapies. We developed a novel tool called the Transcriptome-TCGA Integration (TTI), which combines in vitro transcriptome data with clinical datasets from the Cancer Genome Atlas (TCGA). TTI allows for the identification of key genes and pathways involved in lung cancer, … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 15 Feb 2026 · 1,424 accessesView PDFCite
Research ArticleOpen accessIn the abstractTowards an Explainable Approach: Hybrid Residual Network and SVM for Automated Brain Tumor Detection and ClassificationKamini Lamba, Shalli RaniThe abnormal growth of brain cells leads to tumor formation, which can be fatal if not detected and treated promptly. Given the complexity of brain tumors, early detection is critical in healthcare. Traditional radiology-based tumor detection is prone to human error and delays. Hence, a computer- assisted method is needed for accurate and efficient diagnosis. With the rapid advancements in … …Journal of Computer Science, Vol. 22, Issue 1 · 11 Feb 2026 · 1,427 accessesView PDFCite
Research ArticleOpen accessIn the abstractSignal Pathway Regulation in Mammalian Cells in Wireless Communication EnvironmentShengdong LiTo regulate the signal pathway in mammalian cells in a wireless communication environment, an LED light stimulation system has been designed and constructed. To avoid interference from too many data lines, a wireless communication mode has been employed. In this study, HeLa cells and Drosophila melanogaster cells are used as the research objects. The CRY2/CIBN light genetic element system is … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 2 · 24 Nov 2025 · 2,001 accessesView PDFCite
Research NotesOpen accessIn the abstractNuciferine Attenuates Cigarette Smoke-Induced Senescence in HepG-2 Cells via the miR-217/SIRT1/Nrf2 PathwayYun-Hong Zhao, Yi-Meng Ge, Wei-Jia Xu et al.The lotus leaf, widely used in both medicine and cuisine, contains bioactive compounds with therapeutic potential. Nuciferine (NF), an active constituent of significant importance, is extracted from the lotus leaf. The present study sought to uncover the molecular pathways through which Nuciferine (NF) mitigates cellular senescence triggered by Cigarette Smoke Components (CSCs) in HepG-2 cells, employing an experimental model where … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 2 · 4 Oct 2025 · 2,296 accessesView PDFCite
Research ArticleOpen accessIn the abstractCooling Load Prediction in the Under-Actuated Zone with Multilayer Perceptron Artificial Neural NetworkYaddarabullah, Aedah Abd Rahman, Amna SaadThis study focuses on addressing the challenge of predicting cooling loads in under-actuated zones, where the variability in occupant behavior, environmental conditions, and electronic usage creates complex dynamics. Traditional models like Support Vector Regression (SVR) and E-Lastic-Net (ELN) often struggle to capture these non-linear relationships, leading to inefficient Heating, Ventilation, and Air Conditioning (HVAC) management and increased energy consumption. To … …Journal of Computer Science, Vol. 21, Issue 3 · 27 Jan 2025 · 5,300 accessesView PDFCite
Research ArticleOpen accessIn the abstractDetermination of the Mutagenicity of 2-aminoanthracene Using Chicken Hepatic S-9 FractionVladimir A. Chistyakov, Alexander V. Usatov, Aleksander I. Klimenko et al.The abundance of potential genotoxins makes it necessary to improve microbial test systems that allow to identify these substances quickly. At the same time, the methodology of metabolic activation of promutagens in vitro is very important. Microsomal preparations of rodents, which are generally used for that, have significant disadvantages associated with the potential health risks of the inducers of the … …OnLine Journal of Biological Sciences, Vol. 18, Issue 4 · 16 Nov 2018 · 7,192 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Development of Nanotechnology Bentonite as Adsorbent of Copper Metal (Cu)Susila Arita, Muhammad Naswir, Irma Astriana, NelsonThe aims of the research to develop nanotechnology with the use of bentonite as adsorbent cooper metal (Cu). Bentonite activation treatment performed. The parameters studied in this research is a variation of the mass of bentonite, contact time and adsorption capacity. Measurements were made using AAS. Activation of bentonite using a solution of HCl 1.6 M. In experiments conducted bentonite … …American Journal of Engineering and Applied Sciences, Vol. 11, Issue 2 · 25 May 2018 · 8,655 accessesView PDFCite
Research ArticleOpen accessIn the abstractGenetic Analysis of Bifidobacteriaceae in a Fermented Milk and Colostrum Product in Relation to Immune FunctionMarco RuggieroThis study investigates the microbial composition of a commercially available Swiss fermented milk and colostrum product with a history of use in chronic condition management since 2014. The analysis, performed using the Axiom Microbiome Array, identified a high number of targets corresponding to microbial species classified as probiotics belonging to the Bifidobacteriaceae family. The array provided 28 unique targets, each … …American Journal of Immunology, Vol. 19, Issue 1 · 2 Aug 2024 · 9,049 accessesView PDFCite
Research ArticleOpen accessIn the abstractAspect Based Sentiment Analysis Using Self-Attention Based LSTM Model with Word EmbeddingVimalkumar B. Vaghela, ZishanHaider Y. Noorani, Kalpesh Patel et al.Sentiment analysis is in advance more attention for research due to incremental convention in affairs of state, online marketing and social networking. Users afford their opinions for exacting object as reviews. Analysts categorize these reviews into prejudiced information. Consequently sentiment pulling out is the development of take out human awareness from amorphous text reviews. Extracted sentiment will assist to recognize … …Journal of Computer Science, Vol. 20, Issue 10 · 29 Jul 2024 · 6,512 accessesView PDFCite
Research ArticleOpen accessIn the abstractLogistic Regression with Multi-Connected WeightsAvazjon Marakhimov Rakhimovich, Kabul Khudaybergenov Kadirbergenovich, Zahriddin Muminov Ishkobilovich, Kudaybergenov Jabbarbergen KadirbergenovichResults of current research in biological and cognitive science reveal that neuronal interactions predominantly depend on neurotransmitters for signaling and sending information between neurons. Furthermore, a specific neuron that is connected to the next neuron transmits or sends multiple neurotransmitters in parallel ways, where each neurotransmitter has specific functional roles. Based on these results, a new type of logistic regression … …Journal of Computer Science, Vol. 20, Issue 9 · 4 Jul 2024 · 5,059 accessesView PDFCite