111 articles for “protein design”

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Research ArticleOpen accessIn the abstractSynergistic Effects of Wheat Bran and Inoculants on Fermentation and Nutritional Quality of Soybean Straw SilageLie Yang, Rundong Qin, Jiahuan Liu et al.The efficient valorisation of lignocellulosic biomass from soybean straw into high-quality silage remains a pressing challenge for sustainable livestock production. This study employed a 3×3 factorial design to systematically investigate the interactive effects between wheat bran additions (0%, 10%, 20% of fresh weight) and microbial inoculant regimes (control, Effective Microorganisms, EM+Trichoderma longibrachiatum) on soybean straw silage quality. Two-way ANOVA revealed … …American Journal of Biochemistry and Biotechnology, Vol. 22, Issue 2 · 1 Jul 2026 · 1,118 accessesView PDF Cite

Research ArticleOpen accessIn the abstractIn vitro Rumen Fermentability of the Pelleted Feed Containing Water Spinach (Ipomoea aquatica)Himmatul Hasanah, Eko Pangestu, Ali Agus, Joelal AchmadiAn in vitro technique based on two stages of batch culture was used to clarify fermentability and digestibility of pellet feed containing water spinach (Ipomoea aquatica). The portion of Pennisetum purpureum in the pellet feed was substituted with Ipomoea aquatica at respective levels of 0% (T1), 20% (T2), 40% (T3) and 60% (T4). The treatments were allocated in a completely … …American Journal of Animal and Veterinary Sciences, Vol. 15, Issue 1 · 27 Mar 2020 · 7,562 accessesView PDF Cite

Research ArticleOpen accessIn the abstractMolecular Docking of New Active Compounds Towards the Acetylcholinesterase EnzymeLemaoui Tarek, Hammoudi Nour El Houda, Benguerba Yacine, Attoui AyoubMolecular docking is a key instrument in structural molecular biology and computer-assisted drug design. The objective of ligand-protein docking is to expect the main binding mode(s) of a ligand with a protein of known three-dimensional structure. Effective docking methods search high-dimensional spaces effectively and finding a scoring function that correctly ranks candidate dockings (Morris et al., 2008). In this study … …Current Research in Bioinformatics, Vol. 8, Issue 1 · 27 Feb 2020 · 11,408 accessesView PDF Cite

Research ArticleOpen accessIn the abstractEssential Proteins Discovery Methods based on the Protein-Protein Interaction NetworksLingZhi Zhu, Junling Zhang, Lingya He et al.Essential proteins are closely related to biological survival or reproduction and have important application value in respect of the location of disease genes, disease diagnosis and treatment, drug design. In order to discovery essential proteins, the researchers have proposed experimental approaches, but these methods require laborious and time consuming. With the development of high-throughput sequencing techniques, plenty of computational methods … …American Journal of Biochemistry and Biotechnology, Vol. 13, Issue 4 · 1 Jan 2018 · 8,893 accessesView PDF Cite

Research ArticleOpen accessIn the abstractDifferential Gene Expression of Peroxide Resistant Protein (AhpC) in Planktonic and Biofilm State of Uropathogenic Escherichia coli CellsOmar Sadik Shalal, Ani-Simona SevastreThe gastrointestinal tract seems to be the primary reservoir of Uropathogenic Escherichia coli (UPEC) in humans. UPEC strains harbor the Urinary Tract (UT) and cause Urinary Tract Infections (UTI) which might represent a serious threat to human life. To counteract with the damage caused by the Reactive Oxygen Species (ROS), bacterial strains produce various enzymes and proteins like Alkyl hydroperoxide … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 3 · 13 Oct 2023 · 5,328 accessesView PDF Cite

Research ArticleOpen accessIn the abstractEffects of Dietary Isoleucine Supplementation on the Growth Performance, Carcass Characteristics and Ileal Morphology of Native ChickensCharles Venirius Lisnahan, Oktovianus Rafael Nahak, Lukas PardosiThe roles of isoleucine in the protein synthesis, metabolisms, and growth of chicken have been widely reported. However, its effect on native chicken has not been previously reported. In this work, we reported the effects of dietary isoleucine supplementation on growth performance, carcass characteristics, and ileal morphology in native chickens during the grower phase (6-12 weeks). Two hundred native chickens … …OnLine Journal of Biological Sciences, Vol. 25, Issue 2 · 21 Jun 2025 · 2,945 accessesView PDF Cite

Research ArticleOpen accessIn the abstractImpact of Lighting Durations on Production, Quality, and Fungal Contamination in Green FodderSuci Wulandari, Adib Norma Respati, Satria Budi Kusuma et al.This study aimed to identify hydroponic fodder seeds with optimal production and chemical quality and to determine the fungal species contaminating the green fodder produced. This study used a 2´5 Factorial Completely Randomized Design pattern, with 2 replications. Factor I consisted of two lighting treatments: (1) 12 hours of natural sunlight and (2)24 h of light (natural sunlight followed by … …OnLine Journal of Biological Sciences, Vol. 25, Issue 2 · 3 Jun 2025 · 4,798 accessesView PDF Cite

EditorialOpen accessIn the abstractIs Rerum® the New Coley's Vaccine?Marco RuggieroColey's Vaccine and Cancer Immunotherapy Dr. William B. Coley is credited for having been the first to translate the observation of an association between bacterial infections, high fever and cancer remission into a successful cancer treatment. However, it is worth noting that such an association dates back to at least one century before Coley's times; as Wiemann and Starnes from … …American Journal of Immunology, Vol. 13, Issue 2 · 31 May 2017 · 12,285 accessesView PDF Cite

Research ArticleOpen accessIn the abstractEvaluation of the Effects of the Addition of Salt, Type of Additive and the Shelf Life, on Chemical Composition of Pennisetum purpureum (Schumach) (Maralfalfa) Silages in NigerMaman Lawal Abdoul Aziz, Seydou Korombé Hamza, Djibo Ibrahim et al.Seasonal variations in the quantity and quality of fodder constitute an obstacle to the development of ruminant breeding in Niger. This is why this study was carried out to evaluate the effects of salt addition, shelf life, and type of additive on the chemical composition of Pennisetum purpureum Schumach (Maralfalfa) silages. These aspects were retained because salt, in addition to … …American Journal of Animal and Veterinary Sciences, Vol. 19, Issue 3 · 12 Sep 2024 · 4,729 accessesView PDF Cite

Research ArticleOpen accessIn the abstractSpikelets Fertility and Quality of Local Upland Rice (Oryza sativa L.) Seeds Due to High Temperature at Various StagesRisky Ridha, Ellis Nihayati et al.Stress from high temperatures is one of the factors that restrict rice plant growth and development. Rice generative stage sensitivity to high temperatures is well established, but its vegetative stage sensitivity is more uncertain. To identify high-temperature tolerance traits in the vegetative and generative stages, four local upland rice genotypes were tested under high-temperature stress treatment (32-36°C) during the vegetative … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 22 Jul 2024 · 5,018 accessesView PDF Cite