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55 results for “lymphocytes”
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Research ArticleOpen accessIn the abstractThe Potential of VipAlbumin® to Chronic Inflammation in Type 2 Diabetes Mellitus Balb/C Mice ModelDinia Rizqi Dwijayanti, M. Sasmito Djati, Mansur Ibrahim, Muhaimin Rifa’iDiabetes Mellitus (DM) is one of diseases which have increasing number of sufferers every year. Almost all DM patients are type 2 DM. One of the causes of type 2 DM is a chronic inflammation due to an increase of circulating proinflammatory cytokines such as TNF-α, IFN-γ and IL-6. VipAlbumin® from snakehead fish extract is expected to be useful as … …American Journal of Immunology, Vol. 11, Issue 2 · 13 Jul 2015 · 7,612 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Unilateral Cervical Vagotomy on Murine Dendritic CellsDaniel Sanzio Gimenes da Cruz, Ana Paula Nascimento de Lima, Patrícia Benites Gonçalves da Silva et al.The cholinergic anti-inflammatory pathway has been demonstrated to be an important mechanism that modulates several inflammatory diseases. This modulation occurs upon activation of the vagus nerve, which modulates splenic macrophages and lymphocytes through the predominant neurotransmitter, Acetylcholine (ACh). We hypothesized that this modulation could also take place in dendritic cells, as these cells represent a link between the innate and … …American Journal of Immunology, Vol. 11, Issue 2 · 12 Jul 2015 · 6,948 accessesView PDFCite
Research ArticleOpen accessIn the abstractClinio-Pathological Changes in Goats Challenged with Corynebacterium Peudotuberculosis and its Exotoxin (PLD)Z. K.H. Mahmood, F. F. Jesse, A. A. Saharee et al.Caseous lymphadenitis (CLA) is a chronic disease caused by Corynebacterium pseudotuberculosis. However, there is a paucity of data about the C. pseudotuberculosis exotoxin, phospholipase D (PLD) response during the course of CLA. Therefore, this study was conducted to observe the clinical signs and the cellular changes after an experimental infection of the C. pseudotuberculosis and phospholipase D challenge. Twenty six … …American Journal of Animal and Veterinary Sciences, Vol. 10, Issue 3 · 26 May 2015 · 8,316 accessesView PDFCite
Research ArticleOpen accessIn the abstractActin Cytoskeleton and Related Proteins Role During Immune Cells Migration, Polarity and Activation: An OverviewClaudio Vieira da SilvaImmune cells migration, polarity and activation are essential during host immune response. Upon recognition of specific peptides presented by Human Leukocyte Antigen (HLA) molecules on Antigen Presenting Cells (APC), lymphocytes execute subset-related functions such as killing, help and regulation. These cells travel through the organism in a succession of steps, including entry into tissues, interstitial migration, APC scanning, synapse formation … …American Journal of Immunology, Vol. 9, Issue 4 · 19 Nov 2013 · 6,780 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Comparative Study of the Ovine Haemogram: Cell-Dyn 3500 Versus Manual MethodsLabrini V. Athanasiou, Constantinos G. Giannakopoulos, Zoe S. Polizopoulou et al.Manual hematology techniques traditionally applied in farm animal medicine are time consuming and labor-intensive, especially when large numbers of samples have to be processed. As a result, several automated hematology instruments have been developed for use in these species. An automated hematology analyzer (Abbott Cell-Dyne 3500 system) was used in performing a complete blood cell count and differential counts of … …American Journal of Animal and Veterinary Sciences, Vol. 8, Issue 4 · 23 Oct 2013 · 7,179 accessesView PDFCite
Research ArticleOpen accessIn the abstractLike an Invertebrate Primitive AntibodyMichel LeclercSpecific immune responses occur in an invertebrate: The sea star Asterias rubens. Sea star T and B lymphocytes are present in the axial organ and coopere with phagocytes and Complement components to produce a primitive antibody correlated to Igkappa genes and to complement genes: It could be composed of 4 kappa chains and present strong and highly significant homologies to … …American Journal of Immunology, Vol. 9, Issue 3 · 20 Aug 2013 · 7,043 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvidence of Interleukin Genes in the Sea-Star: Asterias rubens (Echinoderma)Michel Leclerc, Patricia OttenThe axial organ of the sea star Asterias rubens is a primitive immune organ the sea star T lymphocytes, when stimulated by various lectins, produce lymphokin-like substances with mitogenic properties as shown in earlier studies; they are correlated with Interleukin genes. …American Journal of Immunology, Vol. 9, Issue 2 · 22 Jun 2013 · 7,280 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnamnestic Immune Response Eight Years After Immunization of Primates with a Multivalent HIV-1 GP120 Variable Peptide VaccineRebecca Rivera, Kyung Hee Kang, David E. Anderson et al.Successful development of an effective HIV vaccine hasn’t occurred yet partly as a consequence of the antigenic variation deployed by HIV-1 to escape the immune system. Our laboratory is dedicated to develop a single peptide synthesis approach to create multivalent peptides representing hypervariable epitopes of the gp120 envelope glycoprotein of HIV-1. Our previous study showed that our HIV HECs are … …American Journal of Immunology, Vol. 9, Issue 1 · 13 Mar 2013 · 7,209 accessesView PDFCite
Research ArticleOpen accessIn the abstractTargeting Cellular Receptors as a Strategy for the Development of New Generation Mucosal VaccinesConstantine Bitsaktsis, Kari Wiedinger, Edmund Joseph GosselinMucosal pathogens are a primary source of infection that require the development of vaccines to induce a specific, protective and long lasting immune response. Despite an urgent need, development of effective mucosal immunization strategies has proven difficult. The literature was reviewed to elucidate cell specific targets that may be utilized to increase the immunogenicity of protective antigens through mucosal vaccination. … …American Journal of Immunology, Vol. 9, Issue 1 · 2 Feb 2013 · 7,026 accessesView PDFCite
Research ArticleOpen accessIn the abstractRendezvous with Tat: Transactivator of Transcription during Human Immunodeficiency Virus PathogenesisSneham Tiwari, Madhavan P.N. Nair, Shailendra K. SaxenaAcquired immune deficiency syndrome is a deadly disease caused by HIV, declared as a global catastrophe engulfing millions of lives per year. It took ~1.8 million lives in the year 2010 alone, as per reports of UNAIDS. HIV-1 is an enveloped retrovirus, having genome composed of two copies of ssRNA. It attacks the T-lymphocytes of the hosts, causes several multifaceted … …American Journal of Infectious Diseases, Vol. 8, Issue 2 · 31 Jul 2012 · 7,625 accessesView PDFCite