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226 articles for “death”
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Research ArticleOpen accessIn the abstractAdvancing Stroke Lesion Segmentation With U-Net Variants: Classical, Transfer Learning, and MRI Sequence-Specific Customized ApproachesSonia Flora Panesar, Amit P. GanatraIschemic stroke, caused by restricted cerebral blood flow, is a leading cause of death and disability worldwide. Accurate segmentation of stroke lesions in MRI is essential for timely diagnosis but remains labor-intensive when done manually. This study presents a comparative evaluation of three U-Net variants for automated ischemic stroke lesion segmentation using the ISLES 2022 dataset: (1) Classical U-Net with … …Journal of Computer Science, Vol. 22, Issue 2 · 27 Feb 2026 · 1,791 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Metaheuristic-Optimized Feature Selection for Early-Stage Diabetes Prediction With SHAP-Guided Insight into Influential AttributesEsmay Azam Rochy, Jannatul Ferdaus, Uzzal Biswas et al.Diabetes is a metabolic disorder that causes elevated blood glucose. This long-term health condition can lead to cardiovascular diseases, stroke, kidney failure, visual impairment, neuropathy, and even death in critical cases. So, a Computer-Aided Diagnostic (CAD) system is necessary to diagnose diabetes automatically. A clinician can utilize a machine learning-based CAD system that automatically diagnoses many people. This paper will … …Journal of Computer Science, Vol. 22, Issue 2 · 24 Feb 2026 · 1,736 accessesView PDFCite
Literature ReviewOpen accessIn the abstractCorrelation of Atherosclerosis and Osteoarthritis, the Role of Inflammation in the Pathogenesis of Osteoarthritis and AtherosclerosisAnastasia V. Poznyak, Nikolay A. Orekhov, Aleksandra Sergeevna Utkina et al.Cardiovascular Diseases (CVD) rank among the leading causes of death globally, accounting for a substantial proportion of mortality rates and affecting millions of individuals. Risk factors such as ageing, obesity, diabetes and a sedentary lifestyle contribute significantly to the prevalence of CVD. Osteoarthritis (OA), on the other hand, is one of the most common joint disorders, affecting a large segment … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 15 Feb 2026 · 1,769 accessesView PDFCite
Research ArticleOpen accessIn the abstractDihydroartemisinin Attenuates HBV-Induced Proliferation and Migration in LO2 cells via EMT Pathway ModulationYingde Nong, Caifang Ma, Wei Huang et al.Dihydroartemisinin (DHA), a derivative of artemisinin, possesses well-documented anti-inflammatory properties. This study investigated the inhibitory effects of DHA on hepatitis B virus (HBV)-induced cellular alterations in LO2 cells and elucidated underlying molecular mechanisms. Serum interleukin-6 (IL-6) levels were measured in HBV patients and analyzed for correlations with HBsAg, anti-HBs, and HBeAg. In vitro, LO2 cells were infected with clinical HBV … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 3 · 8 Jan 2026 · 2,071 accessesView PDFCite
Research ArticleOpen accessIn the abstractProcalcitonin and Clinical Factors Associated with Severe Dengue Infection in Hospitalized Adults in MalaysiaHuzairi Sani, Nada Syazana, Zahir Izuan et al.Dengue Fever (DF) is the commonest mosquito-borne viral infection that results in hospitalisation amongst patients in Malaysia. The cornerstone of managing dengue virus infection is the prediction hence prevention of severe DF from developing. Warning signs proposed by WHO as clinical predictors of severe DF are insensitive. Procalcitonin (PCT) has been shown to increase in bacterial infections and is useful … …American Journal of Infectious Diseases, Vol. 15, Issue 4 · 3 Dec 2019 · 7,360 accessesView PDFCite
EditorialOpen accessIn the abstractEditorial Commentary: Challenge of Non–AIDS-Defining Cancers (NADCs), Focusing on Trans Activation Response Element (TAR) RNA Embedding ExosomesLechuang Chen, Ge JinGlobally, 37.9 million people were living with HIV at the end of 2018 (Organization, 2018). Cancer is a major cause of mortality and morbidity in AIDS patients and chronically HIV-infected people. With the aid of combination Antiretroviral Therapy (ART), people living with HIV (PLWH) have a longer life span. However, because the virus is not completely eradicated, PLWH under antiretroviral … …American Journal of Immunology, Vol. 15, Issue 1 · 28 Nov 2019 · 6,657 accessesView PDFCite
Review ArticleOpen accessIn the abstractStrategies of Tuberculosis–HIV Vaccines Design using Immunoinformatic ApproachAni Fatonah, Ig. Satrio Wicaksono, Usman Sumo Friend TambunanTuberculosis is amongst the highest cause death worldwide. According to WHO, an estimated of more than a million people fell ill with Tuberculosis (TB) in 2016. The resistances of the M. tuberculosis (MTb) bacteria make drugs, not that useful in battle with TB. Vaccination is a better choice to avoid the worst cases of TB. The resistance possessed by MTb … …OnLine Journal of Biological Sciences, Vol. 19, Issue 2 · 10 May 2019 · 7,925 accessesView PDFCite
Case ReportOpen accessIn the abstractBrief Report: 20-Year Follow-Up of an Infant with Neurological Impairment Born to a Mother with Variant Creutzfeldt-Jakob DiseaseJustin Penner, Anjali Rampersad, James E. Burns et al.A term infant born via uncomplicated caesarian section was noted to be jittery, hypotonic, and have pooling of secretions at birth. Over the first four weeks of life, the infant developed four limb hypertonia, hyperreflexia, and clonus. MRI at 3.5 weeks old showed brain immaturity, poor myelination, and increased signal in the dorsal thalami. At six months, dystonic features with … …American Journal of Infectious Diseases, Vol. 21, Issue 1 · 7 Mar 2025 · 7,660 accessesView PDFCite
Research ArticleOpen accessIn the abstractAn Evaluation of Childhood Overweight Studies from South Africa: A Bibliometric Review from 2003-2023Mere IdamokoroOverweight/obesity exists as a severe threat to the well-being of children globally, with its prevalence in South Africa steadily increasing in recent years. Childhood obesity/overweight can be linked to several life-threatening ailments and, in some cases, death. The present bibliometric review aimed to quantify and map out scholarly outputs on obesity/overweight research published in South Africa through a bibliometric analysis. … …OnLine Journal of Biological Sciences, Vol. 25, Issue 2 · 5 Mar 2025 · 4,904 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Action of Bovine Cartilage on Tumor Cells In Vitro And In VivoArax Tanelian, Alexander M. AbdelnoorIn an earlier study we had investigated the effect of Bovine Cartilage (BC) on mouse melanoma cells. In pursuant to this study BC anti-tumor activity in vitro against several human tumor cell lines was evaluated, mechanism by which BC induces tumor cell death was studied and its immunogenicity was assessed. Five mice received Intraperitoneal (IP) injection of BC once every … …American Journal of Immunology, Vol. 14, Issue 1 · 23 Jan 2018 · 9,664 accessesView PDFCite