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140 results for “c-myc”
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Research ArticleOpen accessEvery word in the titleSpecies Composition and Ecological Roles of Mycobiota in Selected Medicinal Plants of AzerbaijanPanah Z. Muradov, Konul F. Bakhshaliyeva, Nizami R. Namazov et al.About 30 species of medicinal and aromatic plants included in the flora of Azerbaijan have been studied for their mycobiota and the phytotoxic activity of the fungal species involved in their formation. It became clear that 79 fungal species were involved in the formation of the mycobiota of the studied plants, and they, in addition to participating in the formation … …OnLine Journal of Biological Sciences, Vol. 26, Issue 2 · 27 Jul 2026 · 527 accessesView PDFCite
Research ArticleOpen accessEvery word in the titlePurification, Structural Characterization and Anti-Aging and Stress Activities of Cordyceps Mycelium Polysaccharides from Paecilomyces HepialiXiaokang Hu, Huixiu Ma, Guicai Chen et al.This study identified and characterized the bioactive polysaccharide components from Cordyceps mycelium powder (CMP) derived from Paecilomyces hepiali, evaluating their anti-aging and stress-protective activities. Initial screening using Drosophila melanogaster revealed that crude Cordyceps polysaccharides (CCP) exhibited comparable effects to CMP and Cordyceps aqueous extracts (CAE) on natural lifespan and UV stress resistance, suggesting CCP as the primary bioactive component. CCP … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 16 Feb 2026 · 1,698 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleAnalysis of the Utility of MPT64, Drug Susceptibility Testing and Tuberculosis/Nontuberculous Mycobacteria Reverse Transcription Polymerase Chain Reaction for Tuberculosis Diagnosis and Efficiency Compared with Traditional CultureHo Keun Choi, Ga Yeon Kim, Tae Soung Kim, Jae Kyung KimDefining the molecular mechanisms underlying the dormant state of Mycobacterium tuberculosis (MTB) is essential for developing more effective treatments for tuberculosis (TB) infection. We investigated the positivity and resistance rates of TB tests on 6,174 samples referred to a single hospital. Of these, 342 cases (5.5%) were confirmed as positive by acid-fast bacilli staining, 243 cases (71.1%) were detected as … …American Journal of Biochemistry and Biotechnology, Vol. 20, Issue 4 · 5 Dec 2024 · 4,206 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleVirtual Screening of CPP Conjugated Peptide as QcrB BCC Protein Inhibitors of Mycobacterium tuberculosis BacteriaMuhammad Ihsan Muttaqin, Manaman Huang, Usman Sumo Friend TambunanTuberculosis is a global leading cause of death, just below COVID-19 and ranked above HIV. This disease is caused by a pathogen called Mycobacterium tuberculosis, which spreads easily through the air and is known to remain latent in most people's bodies, about a quarter of the world's population. The current problems with TB also include two main concerns: The official … …OnLine Journal of Biological Sciences, Vol. 24, Issue 3 · 14 Mar 2024 · 5,518 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleStudy of Mastitis Incidence in Cows of Dairy Farms in East Kazakhstan: Impacts of Nutrition, Endometritis and Mycotoxin ContaminationNurzhamal Mukhamadieva, Dinara Zainettinova, Mardan Julanov et al.This research aimed to investigate the prevalence, etiological factors, and diagnosis of mastitis in dairy farms located in East Kazakhstan. The study was conducted on two dairy farms, “Balke” and “Madi-R,” and examined a total of 490 cows. The findings indicate that the incidence of clinical and subclinical mastitis varied among the years studied. In 2016, the average incidence was … …American Journal of Animal and Veterinary Sciences, Vol. 18, Issue 4 · 7 Nov 2023 · 5,427 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEvaluation of Antioxidant and Antibacterial Activities of the Polysaccharides from Mycelium and the Culture Medium of Pleurotus Eryngii Strain UN-1Qing Liu, Haodong Wu, Ying Wu et al.Pleurotus eryngii was one of the most precious and ordinary edible mushrooms, and its polysaccharides were the major active substances. In this study, P. eryngii strain UN-1 was cultured in a liquid medium at 25℃ under a shaking of 80 rpm for 7 days. Two crude polysaccharides named CPN and CPNM were obtained from the mycelium of P. eryngii UN-1 … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 3 · 19 Jul 2022 · 6,176 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEffects of Root Rot in Soybean Cultivars with Diverse Susceptibility to the Disease on Plant Physiology, Yield, Amino Acids and Mycotoxins Profile in Climatic Conditions of KazakhstanNurlan Kuldybayev, Yerlan Dutbayev, Bozena Lozowicka et al.Soybean is an important high-value crop but susceptible to soil-borne diseases. A field trial was conducted in Kazakhstan to evaluate the effects of soybean cultivars and Fusarium root rot severity on soybean crop physiology, chlorophyll fractions and amino acids profile. The highest yield was achieved in 2018 (up to 4 t ha-1) for K-9648 cultivar. The greatest root rot severity … …OnLine Journal of Biological Sciences, Vol. 21, Issue 4 · 27 Dec 2021 · 6,299 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleMycobacterium tuberculosis Complex Mutations in Drug Resistant Clinical Isolates from Southwest MexicoMartínez-Cruz Perla Mónica, Nakamura-López Yuko, Quintero-Hernández Verónica et al.Mutations in target genes have been described in Mycobacterium tuberculosis Complex (MTBc) drug resistant isolates worldwide. In Mexico, not enough information has been reported in this concern. The aim of this study was to characterize mutations related to resistance to first line drugs in MTBc isolates from Oaxaca, Mexico. MTBc isolates were identified in clinical samples from Tuberculosis (TB) patients. … …American Journal of Infectious Diseases, Vol. 17, Issue 4 · 28 Oct 2021 · 6,667 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleELISA-Based Development of Functional Antibodies for the Efficient Detection of Mycotoxigenic Fusarium (F. oxysporum and F. circinatum) and Diplodia (D. pinea) SpeciesPhumzile Mkhize, Phetole MangenaFusarium contains the most toxigenic and important fungal pathogens, producing a wide range of mycotoxins that include the more toxic secondary metabolites called fumonisins. This study analyzed the presence of common exo- and mycelium-soluble antigens, purified proteins using reducing SDS-PAGE and the expression of antibodies against different fungal pathogens. The results showed the presence of common antigens between pathogens and … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 4 · 18 Nov 2020 · 6,601 accessesView PDFCite
Research ArticleOpen accessEvery word in the titleEfficient Production of Glycosylated and Non-Glycosylated Mycobacterium tuberculosis Antigen 85B Fused to PVX Coat Protein in Nicotiana benthamiana PlantsPablo A. González, Franco D. Puccio, Alicia M. ZeladaThe development of alternative subunit based-vaccines against tuberculosis is necessary due to variable efficiency and some security concerns of the BCG vaccine. The aim of this work was evaluate the production of the Mycobacterium tuberculosis Ag85B antigen fused to Potato Virus X Coat Protein (PVX-CP) by transient expression in Nicotiana benthamiana for subunit-based tuberculosis vaccine formulation. A codon-optimized M. tuberculosis … …American Journal of Biochemistry and Biotechnology, Vol. 14, Issue 4 · 13 Nov 2018 · 9,976 accessesView PDFCite