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77 results for “apoptosis”
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Research ArticleOpen accessIn the keywordsDetection of HCV Components and Pathological Reactions in Apoptotic Hepatocytes from Chronically HCV-infected PatientsViviana Falcón, Nelson Acosta-Rivero, Mineko Shibayama et al.Analysis of Hepatitis C Virus (HCV)-infected hepatocytes at the cellular level may contribute to elucidate the mechanisms of HCV pathogenesis. In this work, the presence of HCV components and pathological reactions in apoptotic hepatocytes from chronic HCV-infected patients were studied by electron microscopy and confocal microscopy. Eight samples of liver biopsies from patients with chronic hepatitis C were studied by … …American Journal of Infectious Diseases, Vol. 1, Issue 1 · 31 Mar 2005 · 6,907 accessesView PDFCite
Research ArticleOpen accessIn the keywordsTherapeutic Effects of Turnera diffusa Extract Against Amitriptyline-Induced Toxic Hepatic InflammationAhmed F. Hasan, Thulfiqar F. Mutar, Ehab Moustafa Tousson, Shatha Ghazi FelembanTricyclic Antidepressants Including Amitriptyline (AMI), stop the reabsorption of norepinephrine and serotonin, so the levels of transmitters is elevated in the brain to lead to several side effects. Therefore, current study aimed to assay liver dysfunction that attended by AMI administration and monitoring of damiana Turnera diffuse role as adjuvant therapy to improving amitriptyline hepatic effects in male rats. 60 … …OnLine Journal of Biological Sciences, Vol. 21, Issue 2 · 29 Jun 2021 · 8,286 accessesView PDFCite
Research ArticleOpen accessIn the keywordsImpact of Euphorbia helioscopia Extract Administration on Diabetes Induced by Alloxan in MiceDoha Mohammad Beltagy, Amira Mohammed Beltagy, Mohammad Ramadan et al.Diabetes describes metabolic disorder with hyperglycemia and neurotic changes. This work aimed to evaluate the protective effect of total ethanolic extract of Euphorbia helioscopia grown in Egypt against pancreas and brain injuries in diabetic mice induced by alloxan. This work was carried out on 60 mice divided into four groups. Control Group (G1) included healthy normal mice that did not … …OnLine Journal of Biological Sciences, Vol. 20, Issue 3 · 19 Oct 2020 · 6,406 accessesView PDFCite
Research ArticleOpen accessIn the keywordsCYTOTOXICITY AND MODE OF CELL DEATH INDUCED BY TRIPHENYLTIN (IV) COMPOUNDS IN VITRONormah Awang, Zalila Abdul Aziz, Nurul Farahana Kamaludin, Kok Meng ChanA series of newly synthesized organotin (IV) with N-alkyl-N-phenyldithiocarbamate ligands namely triphenyltin (IV) ethylphenyldithiocarbamate (compound 1) and triphenyltin (IV) butylphenyldithiocarbamate (compound 2) were assessed for their cytotoxic effect against HT-29 human colon adenocarcinoma cells and human CCD-18Co normal colon cells. The cytotoxicity of these organotins in both cells was assessed using 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazholium bromide (MTT) assay upon 24 h treatment. … …OnLine Journal of Biological Sciences, Vol. 14, Issue 2 · 15 Mar 2014 · 8,746 accessesView PDFCite
Research ArticleOpen accessIn the keywordsStudy of pH and Cellular Response in Pulmonary Fibroblasts After Exposure to Market Street World Trade Center Particulate MatterMichelle Hernandez, Sung Choi, Ann Marie DiLorenzoChronic health conditions have been noted among first responders and residents exposed to the dust generated from the World Trade Center (WTC) collapse on September 11, 2001. This study sought to isolate a single factor thought to play a substantial role in the decreased lung function of World Trade Center (WTC) workers and victims. Human pulmonary fibroblasts were exposed to … …OnLine Journal of Biological Sciences, Vol. 12, Issue 4 · 8 Feb 2013 · 7,322 accessesView PDFCite
Research ArticleOpen accessIn the keywordsQuantum Stem Cell in the Infinity Loop: A New Concept for Our Understanding of the Normal State and CancerKambiz AfrasiabiProblem statement: The scientific community is in need of more rigorous understanding of the mechanism of initiation of mitosis. The complete understanding of the initiation sequence may allow knowledge of the normal and disease states, including cancer. This understanding and knowledge would open the way for developing curative treatment of cancer. This article proposes a mechanism of initiation of mitosis … …OnLine Journal of Biological Sciences, Vol. 10, Issue 2 · 17 Mar 2010 · 8,964 accessesView PDFCite
Research ArticleOpen accessIn the keywordsThe Tumor/Immune Interface: Clinical Evidence of Cancer Immunosurveillance, Immunoediting and ImmunosubversionMatthew S. Block, Svetomir N. MarkovicProblem statement: The interactions of a malignant tumor with the patient’s immune system are dynamic, multiple and bi-directional. Approach: This article reviews the clinical evidence of the interaction of cancer with immunity with emphasis on recent developments highlighting some of the mechanisms of tumor-mediated regulation of immunity. Results: Most of the time, the immune response to a malignancy acts to … …American Journal of Immunology, Vol. 5, Issue 1 · 31 Mar 2009 · 10,095 accessesView PDFCite
Research ArticleOpen accessIn the keywordsEmetine produce Entamoeba histolytica Death by Inducing a Programmed Cell DeathJ.D. Villalba-Magdaleno, R. Rojas, C. Gómez et al.Amoebiasis is a major public health problem in tropical and subtropical countries. Although a number of antiamoebic agents are used for its treatment and the molecular targets of these drugs have been identified, the biochemical and physiological mechanisms that produce trophozoite death are little known. The present study dates the in vitro induction of programmed cell death (PCD) in E. … …American Journal of Infectious Diseases, Vol. 3, Issue 2 · 30 Jun 2007 · 7,211 accessesView PDFCite
Research ArticleOpen accessIn the keywordsCirculating Granzymes are associated with Bloodstream Infection and Death in Febrile Medical PatientsAnnelies N. Tacx, Angela M. Wolbink, C. E. Hack, A.B. Johan GroeneveldPlasma levels of granzymes are specific markers for the activation of cytotoxic T lymphocytes and natural killer (NK) cells but the impact of activation of these cells on the course of bacterial infections is not well understood. We prospectively studied the implications of circulating granzyme A and B (GrA, GrB) levels in febrile, medical and hospitalized patients (n=284), during 3 … …American Journal of Infectious Diseases, Vol. 3, Issue 1 · 31 Mar 2007 · 6,736 accessesView PDFCite
Research ArticleOpen accessIn the keywordsRETRACTED: Review of Prodigiosin, Pigmentation in Serratia marcescensAnita Khanafari, Mahnaz M. Assadi, Fatemeh A. FakhrThe Online Journal of Biological Sciences has decided to retract the manuscript titled "Review of Prodigiosin, Pigmentation in Serratia marcescens" authored by Anita Khanafari, Mahnaz M. Assadi, and Fatemeh A. Fakhr, published in Volume 6, Issue 1 with the page numbering 1-13. After receiving a complaint, the editorial office found that the manuscript contains plagiarized material from the manuscript entitled … …OnLine Journal of Biological Sciences, Vol. 6, Issue 1 · 30 Jun 2006 · 17,480 accessesView PDFCite