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58 results for “Type 2 Diabetes”
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Research ArticleOpen accessIn the abstractUnveiling the Potential of Dombeya buettneri K.Schum As a Drug Agent: Molecular Docking of Compounds With Enzymes Linked to Diabetes and Neurodegenerative DiseaseEsther Emem Nwanna, Samuel Chima Ugbaja et al.This study investigated the mechanisms of Dombeya buettneri (snowball leafy) extracts on diabetes, hypertension, and neurodegenerative diseases. It compared extracts obtained using steep water (a by-product of corn wet milling) and aqueous water. The extracts were analyzed for total phenol, total flavonoid content, antioxidant activities such as FRAP, ABTS, NO, DPPH, iron-induced lipid peroxidation assay, degradation of deoxyribose (Fenton’s reaction), … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 1 Feb 2026 · 2,025 accessesView PDFCite
Research ArticleOpen accessIn the abstractLogistic Regression with Multi-Connected WeightsAvazjon Marakhimov Rakhimovich, Kabul Khudaybergenov Kadirbergenovich, Zahriddin Muminov Ishkobilovich, Kudaybergenov Jabbarbergen KadirbergenovichResults of current research in biological and cognitive science reveal that neuronal interactions predominantly depend on neurotransmitters for signaling and sending information between neurons. Furthermore, a specific neuron that is connected to the next neuron transmits or sends multiple neurotransmitters in parallel ways, where each neurotransmitter has specific functional roles. Based on these results, a new type of logistic regression … …Journal of Computer Science, Vol. 20, Issue 9 · 4 Jul 2024 · 5,059 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Effect of Gliflozin Therapy on TNF-α Secretion by Cultured Monocytes in Patients with DiabetesTatiana Vladimirovna Kirichenko, Leyla Azimovna Bochkareva et al.Currently it’s well established that chronic inflammation is a key pathogenetic mechanism in the development of Type 2 diabetes. The study aims to explore the inflammatory response of monocytes in diabetic patients compared to healthy subjects, focusing on TNF-α and to investigate the impact of SGLT2 inhibitors on monocyte inflammation. The study included 20 patients with newly diagnosed type 2 … …OnLine Journal of Biological Sciences, Vol. 24, Issue 3 · 15 Feb 2024 · 4,819 accessesView PDFCite
Research ArticleOpen accessIn the abstractModel Classification for Predicting the Post-Translational Modification (PTM) Glycosylation in Sequence O Using an Extreme Gradient Boosting AlgorithmDamayanti, Sutyarso et al.Post Translational Modification (PTM) is an important mechanism involved in regulating protein function. Post-translational modification refers to the addition of covalent and enzymatic modifications of proteins in protein biosynthesis, which has an important role in modifying protein function and regulating gene expression. One of the post-translational modifications is glycosylation. Glycosylation is the addition of a sugar group to a protein … …Journal of Computer Science, Vol. 20, Issue 7 · 29 Apr 2024 · 5,554 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of Mir 29c-3p and Mir 31-5p Serum Values in Predicting Nephropathy in Type 2 Diabetic PatientsMona S. Habieb, Nesreen Gamal Elhelbawy, Khaled M. Elzorkany et al.Diabetic Nephropathy (DN) is a prime complication of diabetes with various pathological mechanisms. microRNAs (miRNAs) have emerged as an important factor in the pathogenesis of renal disorders. We aimed to analyze serum miR 29c-3p and miR 31-5p in diabetic patients in relation to albuminuria and eGFR. Also, the correlations between these miRNAs and cystatin C were assessed. This study was … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 1 · 17 Feb 2022 · 6,449 accessesView PDFCite
Literature ReviewOpen accessIn the abstractThe Benefits of Selected Nutritional Compounds Towards Atherosclerosis ManagementAnastasia Vladimirovna Poznyak, Mariam Bagheri Ekta, Vasily Nikolaevich Sukhorukov et al.Globally, the prevalence of obesity, type 2 diabetes, and metabolic syndrome is steadily rising, potentially giving rise to the most extensive non-communicable health crisis ever recorded blocking the flow are able to break and cause a blood clot. The possible consequence is a significant increase in atherosclerotic cardiovascular disease rate. The atherosclerotic cardiovascular disease largely depends on modifiable factors, however, … …OnLine Journal of Biological Sciences, Vol. 24, Issue 1 · 2 Nov 2023 · 5,032 accessesView PDFCite
Research ArticleOpen accessIn the abstractPredictive Modeling Applied to Structured Clinical Data Extracted from Electronic Health Records: An Architectural Hypothesis and A First ExperimentAlessandra Pieroni, Alessandro Cabroni, Francesca Fallucchi, Noemi ScarpatoPredictive analysis is one of current important issues in the healthcare context. A lot of patients’ input data can be obtained from their Electronic Health Records. In our research, we propose a general architecture named Health Prediction Architecture. Initially, we consider that data refer to strongly structured health datasets (no free text). Our objectives are related to exploring some problems … …Journal of Computer Science, Vol. 17, Issue 9 · 7 Sep 2021 · 6,571 accessesView PDFCite
Case ReportOpen accessIn the abstractPortal Vein Thrombosis: A Saga of two Nebulous EtiologiesAshwin Parchani, Manjunath Totaganti, Prasan Kumar Panda, Sunil Kumar KSPortal Vein Thrombosis (PVT) is the most prevalent cause of extrahepatic portal vein obstruction. Cirrhosis, inherited procoagulant conditions (such as Factor V Leiden, Antithrombin III deficiency, etc.), myeloproliferative neoplasms, hepatocellular carcinoma and operative manipulation of the portal vein are all common causes of portal vein thrombosis. Even though a diagnosis is usually made, more than 25% of patients have no … …American Journal of Infectious Diseases, Vol. 18, Issue 1 · 26 Mar 2022 · 6,180 accessesView PDFCite
Research ArticleOpen accessIn the abstractDiabetic Retinopathy Detection using Deep Learning TechniquesAswin Shriram Thiagarajan, Jithendran Adikesavan, Santhi Balachandran, Brindha Ganapathyagraharam RamamoorthyDiabetic Retinopathy is a type of eye condition induced by diabetes, which damages the blood vessels in the retinal region and the area covered with lesions of varying magnitude determines the severity of the disease. It is one of the most leading causes of blindness amongst the employed community. A variety of factors are observed to play a role in … …Journal of Computer Science, Vol. 16, Issue 3 · 13 Mar 2020 · 10,272 accessesView PDFCite
EditorialOpen accessIn the abstractFocalize the Structure of Myd88 in TLR Signaling Pathway to Modulate Innate Immune Response: New Target for Old DiseasesShuai Xing, Ping ZhouAll diseases have their Achilles’ Heel to target and this is especially true for immunorelated diseases which must be treated by targeting the immune system somewhere and somehow correctly. In the most recent decade, immunologists recognized that the Toll-Like Receptor (TLR) signaling pathway in innate immune system plays a double-edged role in the pathogenesis of many notorious diseases. Although the … …American Journal of Immunology, Vol. 13, Issue 3 · 6 Sep 2017 · 7,862 accessesView PDFCite