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175 results for “Therapeutic Effect”
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Research ArticleOpen accessIn the abstractEvaluating the Hepatoprotective and Anti-Inflammatory Efficacy of Herbal Extracts for NAFLD PreventionHessah Mohammed Al-Muzafar, Kamal Adel AminNatural products may offer a safer approach for mitigating the increasing prevalence of Non-Alcoholic Fatty Liver Disease (NAFLD). This study aimed to evaluate the hepatoprotective and anti-inflammatory effects of a water-based extract of Moringa Oleifera leaf, Milk Thistle, and Cassia (MO-MT-CA) against High-Fat, High-Sugar Diet (HFSD)-induced fatty liver. The research focuses on assessing lipid profiles and inflammation as key markers … …OnLine Journal of Biological Sciences, Vol. 25, Issue 3 · 23 Nov 2025 · 1,968 accessesView PDFCite
Research ArticleOpen accessIn the abstractAssessment of Asthma Control in Children During the COVID-19 Pandemic: A Cross-Sectional Study at a Pediatric Hospital in Marrakech (Morroco)Maryem Labyad, Karima El Fakiri, Abdelmounaim Baslam et al.Effective management of childhood asthma relies on regular and objective assessments to ensure optimal control. However, the implementation of containment measures during the COVID-19 pandemic has led to the postponement of pediatric consultations, posing significant challenges for children with asthma. This study aimed to evaluate asthma control among children attending pediatric consultations at the mother-child hospital in Marrakech during the … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 5 Jun 2024 · 4,895 accessesView PDFCite
Research ArticleOpen accessIn the abstractClinical Significance of Precise Hyperthermic Intraperitoneal Chemotherapy Up-regulation RP11-356I2.2 Restraining the Occurrence and Development of Gastric CancerYu Yan, Feng Yanlin, Feng Jinxin et al.In order to study the therapeutic effect and possible mechanism of Precise Hyperthermic Intraperitoneal Chemotherapy (HIPEC) on gastric cancer, the expression of RP11-356I2.2 in gastric cancer cell lines and tissues was detected by real-time fluorescence quantitative PCR (RT-PCR). Chi-square test was used to analyze the correlation between the expression and clinic pathological parameters. Western blotting was used to detect the … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 2 · 4 Jun 2020 · 6,487 accessesView PDFCite
Research ArticleOpen accessIn the abstractImpact of Coriander Seeds Extract Against Thyroidectomy Induced Testicular Damage and DNA Replication in Male RatsAzhar Azher Alankooshi, Ahmed F. Hasan et al.An important target organ for thyroid hormone activity is the testis and hypo or hyperthyroidism causes noticeable alterations in testicular function. This study aimed to investigate the therapeutic effect of Coriander Seeds Extract (CSE) against thyroidectomy induced toxicity, oxidative stress, injury, and proliferation in male testes rats. 40 male rats were equally divided into 4 groups [Gp1, control; Gp2, CSE; … …OnLine Journal of Biological Sciences, Vol. 23, Issue 2 · 3 Apr 2023 · 6,611 accessesView PDFCite
Research ArticleOpen accessIn the abstractProduction of an Achillea millefolium (Yarrow) Toothpaste to Combat Gum and Tooth PainMunashe K. F. Chakamanga, Ashley Kumalo K, Dirk Hamadziripi MGum inflammation also known as gingivitis is primarily caused by the accumulation of dental plaque that forms on teeth. The inflammation triggers pain in the gums and surrounding tissues due to increased blood flow and immune activity aimed at combating the bacterial infection. Thus, this study was carried out to investigate the efficacy of Yarrow-based toothpaste in reducing gum inflammation. … …OnLine Journal of Biological Sciences, Vol. 26, Issue 4 · 9 Oct 2026 · 420 accessesView PDFCite
Review ArticleOpen accessIn the abstractThe Intricate Relationship between Obesity and Type 2 DiabetesAnastasia V. Poznyak, Elizaveta M. Pleshko, Aleksandra S. Utkina et al.The rising prevalence of obesity and type 2 diabetes mellitus (T2DM) has emerged as one of the most pressing global public health challenges, profoundly impacting various demographic groups worldwide. This review synthesizes recent epidemiological data and explores the intricate biochemical mechanisms linking obesity to T2DM. We highlight the multifactorial nature of obesity, characterized by excessive adipose tissue, systemic inflammation, and … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 9 Aug 2026 · 455 accessesView PDFCite
Research ArticleOpen accessIn the abstractStudy of Ageratum conyzoides L. (Asteraceae) Phytochemical Composition as Quorum-sensing Inhibitors to Combat Antibiotic-resistant Bacterial InfectionsEli Compaoré, Lassané Ouedraogo, Ablassé Rouamba et al.The rise of antibiotic-resistant bacterial infections has intensified the search for plant-derived quorum-sensing (QS) inhibitors as alternative therapeutic strategies. Ageratum conyzoides L. has a long history of traditional use as an antimicrobial agent against multidrug-resistant pathogens, yet the phytochemical basis of its QS-inhibitory activity remains incompletely characterized. This study aimed to investigate the phytochemical composition of A. conyzoides and evaluate … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 3 Apr 2026 · 1,772 accessesView PDFCite
Review ArticleOpen accessIn the abstractRole of HDL in Atherogenesis: Cholesterol and AtheroprotectionAnastasia Vladimirovna Poznyak, Vasily Nikolaevich Sukhorukov, Victor Yurievich Glanz et al.Atherosclerosis is a major global health burden, responsible for a significant proportion of cardiovascular morbidity and mortality worldwide. Its high prevalence and severe clinical consequences have made it a subject of extensive research. Despite considerable advances, the complexity of its pathogenesis continues to hinder the development of effective preventive strategies and therapeutic interventions. Current evidence implicates chronic inflammation, dysregulated lipid … …OnLine Journal of Biological Sciences, Vol. 26, Issue 1 · 3 Apr 2026 · 1,476 accessesView PDFCite
Research ArticleOpen accessIn the abstractMorphological Changes in Brain Tissue During Experimental HypoxiaAizhan Mussayeva, Ulbossin Kozhaniyazova, Laura Koibasova et al.The extensive application of hypoxic training to enhance cerebral circulation highlights its significant role in effectively realizing the therapeutic and health-promoting benefits of this method. The discrepancy between the data on the features of cerebral circulation and cellular metabolism in brain tissues during circulatory hypoxia and significant interest in the physiological patterns of the integrative response of the body determined … …OnLine Journal of Biological Sciences, Vol. 25, Issue 4 · 20 Feb 2026 · 1,552 accessesView PDFCite
Research ArticleOpen accessIn the abstractEpigenetic Regulation of Extracellular Matrix Remodeling in Skin Aging: Mechanisms and InteractionsJiguang Yang, Yusong Shi, Xiaoqing YanSkin aging results from complex interactions between genetic factors, environmental stressors, and epigenetic modifications that regulate extracellular matrix (ECM) remodeling. Accumulation of senescent cells impairs tissue regeneration through mechanisms including telomere shortening, reactive oxygen species accumulation, and ultraviolet (UV) radiation exposure. While epigenetic pathways regulate skin homeostasis, regeneration, and senescence, the specific epigenetic changes occurring during UV exposure, chronological aging, … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 15 Feb 2026 · 1,458 accessesView PDFCite