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72 articles for “Targeting”
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EditorialOpen accessIn the abstractFocalize the Structure of Myd88 in TLR Signaling Pathway to Modulate Innate Immune Response: New Target for Old DiseasesShuai Xing, Ping ZhouAll diseases have their Achilles’ Heel to target and this is especially true for immunorelated diseases which must be treated by targeting the immune system somewhere and somehow correctly. In the most recent decade, immunologists recognized that the Toll-Like Receptor (TLR) signaling pathway in innate immune system plays a double-edged role in the pathogenesis of many notorious diseases. Although the … …American Journal of Immunology, Vol. 13, Issue 3 · 6 Sep 2017 · 7,862 accessesView PDFCite
EditorialOpen accessIn the abstractIs Rerum® the New Coley's Vaccine?Marco RuggieroColey's Vaccine and Cancer Immunotherapy Dr. William B. Coley is credited for having been the first to translate the observation of an association between bacterial infections, high fever and cancer remission into a successful cancer treatment. However, it is worth noting that such an association dates back to at least one century before Coley's times; as Wiemann and Starnes from … …American Journal of Immunology, Vol. 13, Issue 2 · 31 May 2017 · 12,281 accessesView PDFCite
Research ArticleOpen accessIn the abstractMonetary Policy in a Markov-Switching VECM: Implications for the Cost of Disinflation in GhanaRichard Kwabi Ayisi, Joseph AduMonetary policy assessment in Ghana has been conducted using vector auto-regression. This however, presumes stability of long run outcomes and particularly ignores monetary policy regime changes that has characterized the economy overtime. This study thus introduced the possibility of switches in the long run equilibrium in co-integrated vector auto-regression by allowing both the covariance and weighting matrix in the error-correction … …American Journal of Economics and Business Administration, Vol. 8, Issue 2 · 18 Mar 2017 · 8,548 accessesView PDFCite
Research ArticleOpen accessIn the abstractPerformance Comparison of Passive Fault Tolerant Control Strategy with PI and Fuzzy Control of Single-Tank Level Process with Sensor and System FaultHimanshukumar R. Patel, Vipul A. ShahFault-Tolerant Control (FTC) strategy has gain maximum attention in recent years in chemical industries due to economical and safety hazards perspective. Targeting at the decreasing control performance of the single-tank level control process under the constraint of system and sensor faults, this article presents model-based Passive Fault-Tolerant Control (PFTC) strategy which are based on conventional and artificial intelligence control. The … …American Journal of Engineering and Applied Sciences, Vol. 12, Issue 2 · 24 Jun 2019 · 7,598 accessesView PDFCite
Research ArticleOpen accessIn the abstractDesigning a Comprehensive Security Framework for Smartphones and Mobile DevicesNader Jafari, Abeer Alsadoon, Chandana Prasad Withana et al.This work investigates issues and challenges of cyber security, specifically malware targeting mobile devices. Recent advances in technology have provided high CPU power, large storage, broad bandwidth and integrated peripheral devices such as Bluetooth, Wi-Fi, 3G/4G to mobile devices, making them popular computing and communication devices. Mobile malware has been targeting mobile devices more than ever and seems to be … …American Journal of Engineering and Applied Sciences, Vol. 9, Issue 3 · 3 Oct 2016 · 8,037 accessesView PDFCite
EditorialOpen accessIn the abstractAre Heat Shock Proteins Druggable Candidates?Tawanda Zininga, Addmore ShonhaiBanumathy, G., V. Singh, S.R. Pavithra and U. Tatu, 2003. Heat shock protein 90 function is essential for Plasmodium falciparum growth in human erythrocytes. J. Biol. Chem., 278: 18336-18345. DOI: 10.1074/jbc.M211309200 Brehmer, D., S. Rudiger, C.S. Gassler, D. Klostermeier and L. Packschies et al., 2001. Tuning of chaperone activity of Hsp70 proteins by modulation of nucleotide exchange. Nature Structural Molecular … …American Journal of Biochemistry and Biotechnology, Vol. 10, Issue 4 · 2 Dec 2014 · 8,166 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of ced-9 dsRNA on Caenorhabditis elegans and Meloidogyne incognitaRobert T. Gaeta, Abdellatif Bahaji, Glenda W. Polack, Alejandro Calderón-UrreaAbstract: Problem Statement: In metazoans Programmed Cell Death (PCD) is essential for proper development. Suppression of PCD is needed to guarantee cell survival and in the nematode Caenorhabditis elegans the regulation of PCD is accomplished by the function of the ced-9 gene. Approach: In this work the use of double stranded RNA (dsRNA) to knock-down ced-9 gene function was tested … …American Journal of Agricultural and Biological Sciences, Vol. 6, Issue 1 · 15 Dec 2010 · 9,452 accessesView PDFCite
Research ArticleOpen accessIn the abstractEmpirical Analysis of Virtual Carrier Sense Flooding Attacks Over Wireless Local Area NetworkMina Malekzadeh, Abdul Azim Abdul Ghani, Jalil Desa, Shamala SubramaniamProblem statement: Wireless Local Areas (WLANs) are subject to different types of vulnerabilities. Denial of Service (DoS) attack is the most current challenging issue on the WLANs. The objectives of the study were to (i) Provide an empirical analysis to conduct a series of wireless virtual carrier sense DoS attacks using wireless control frames vulnerabilities, (ii) Design a testbed to … …Journal of Computer Science, Vol. 5, Issue 3 · 31 Mar 2009 · 7,650 accessesView PDFCite
Research ArticleOpen accessIn the abstractVariations in Pathogenicity and Molecular Characterization of Infectious Bursal Disease Virus (IBDV) In EgyptMahmoud E. Sedeik, Ashraf M. Awad, Heba Rashed, Wael K. ElfeilInfectious bursal disease consider a vital threat to poultry industry worldwide and It has special potentiality in Egypt as the country become endemic with several clades from avian influenza from both types highly pathogenic (H5N1 and H5N8) and low pathogenic one (H9N2). The Egyptian government depends on the inactivated vaccine strategy to control avian influenza and any infection with IBD … …American Journal of Animal and Veterinary Sciences, Vol. 13, Issue 2 · 18 May 2018 · 8,479 accessesView PDFCite
Review ArticleOpen accessIn the abstractNikola TESLARelly Victoria Virgil Petrescu, Raffaella Aversa, Antonio Apicella et al.Nicolae Tesla, has remained and spent most of his life, making it hard to pronounce "Teslea"), is considered to be the inventor of the alternating current and uncovered cableless power transmission. It is attributed to the transmission of energy through monophase, biphasic, polyphase alternating currents and transmission of non-wired energy by electromagnetic waves (oscillations) in the industrial alternating current frequency … …American Journal of Engineering and Applied Sciences, Vol. 10, Issue 4 · 6 Nov 2017 · 13,193 accessesView PDFCite