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61 results for “Structure Prediction”

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Research ArticleOpen accessIn the abstractUnbalance Quantitative Structure Activity Relationship Problem Reduction in Drug DesignD. Pugazhenthi, S. P. RajagopalanProblem statement: Activities of drug molecules can be predicted by Quantitative Structure Activity Relationship (QSAR) models, which overcome the disadvantage of high cost and long cycle by employing traditional experimental methods. With the fact that number of drug molecules with positive activity is rather fewer than that with negatives, it is important to predict molecular activities considering such an unbalanced … …Journal of Computer Science, Vol. 5, Issue 10 · 31 Oct 2009 · 6,704 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Survey of Compute Intensive Algorithms for Ribo Nucleic Acids Structural DetectionRa’ed Al-Khatib, Rosni Abdullah, Nur’Aini Abdul RashidProblem statement: Finding an accurate RNA structural alignment from primary sequence due to it is time consuming and computationally NP-hard problem is a major bioinformatics challenge. According to our investigation majority of current researches were concerned on achieving faster execution time, improving space complexity and better cache management. Recently one research introduced cache-efficient Chip Multiprocessor (CMP) algorithms with good speed-up … …Journal of Computer Science, Vol. 5, Issue 10 · 31 Oct 2009 · 6,458 accessesView PDFCite
Research ArticleOpen accessIn the abstractForecasting Gold Prices Using Multiple Linear Regression MethodZ. Ismail, A. Yahya, A. ShabriProblem statement: Forecasting is a function in management to assist decision making. It is also described as the process of estimation in unknown future situations. In a more general term it is commonly known as prediction which refers to estimation of time series or longitudinal type data. Gold is a precious yellow commodity once used as money. It was made … …American Journal of Applied Sciences, Vol. 6, Issue 8 · 31 Aug 2009 · 11,091 accessesView PDFCite
Research ArticleOpen accessIn the abstractFinite Element Analysis of the Crack Propagation for Solid MaterialsMiloud Souiyah, A. Muchtar, Abdulnaser Alshoaibi, A. K. AriffinProblem statement: The use of fracture mechanics techniques in the assessment of performance and reliability of structure is on increase and the prediction of crack propagation in structure play important part. The finite element method is widely used for the evaluation of SIF for various types of crack configurations. Source code program of two-dimensional finite element model had been developed, … …American Journal of Applied Sciences, Vol. 6, Issue 7 · 31 Jul 2009 · 7,842 accessesView PDFCite
Research ArticleOpen accessIn the abstractDurability Assessment of Cylinder Block for Two Stroke Free Piston Linear Engine using Random LoadingM. M. Rahman, A. K. Ariffin, S. Abdullah et al.This research presents the durability assessment of cylinder block for a two-stroke free piston engine using narrow band approach. The life prediction results are worthy for improving the component design at the very early developing stage. This approach is adequate for periodic loading, however, requires very large time records to accurately describe random loading processes. Fatigue damage in conventionally determined … …American Journal of Applied Sciences, Vol. 6, Issue 4 · 30 Apr 2009 · 7,454 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Survey of Protein Fold Recognition AlgorithmsMohammed Said Abual-Rub, Rosni AbdullahProblem statement: Predicting the tertiary structure of proteins from their linear sequence is really a big challenge in biology. This challenge is related to the fact that the traditional computational methods are not powerful enough to search for the correct structure in the huge conformational space. This inadequate capability of the computational methods, however, is a major obstacle in facing … …Journal of Computer Science, Vol. 4, Issue 9 · 30 Sep 2008 · 6,877 accessesView PDFCite
Research ArticleOpen accessIn the abstractProtein Molecular Structures, Protein SubFractions, and Protein Availability Affected by Heat Processing: A ReviewPeiqiang YuThe utilization and availability of protein depended on the types of protein and their specific susceptibility to enzymatic hydrolysis (inhibitory activities) in the gastrointestine and was highly associated with protein molecular structures. Studying internal protein structure and protein subfraction profiles leaded to an understanding of the components that make up a whole protein. An understanding of the molecular structure of … …American Journal of Biochemistry and Biotechnology, Vol. 3, Issue 2 · 30 Jun 2007 · 8,286 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Meaning of a Redundant Codon: There is Protein Folding Information in Nucleic Acids in Addition to the Genetic CodeJan C. Biro, Josephine M.K. BiroAll the information necessary for protein folding is supposed to be present in the amino acid sequence. It is still not possible to provide specific ab initio structure predictions by bioinformatical methods. It is suspected that additional folding information is present in protein coding nucleic acid sequences, which is not represented by the known genetic code. Nucleic acid subsequences comprising … …American Journal of Biochemistry and Biotechnology, Vol. 2, Issue 1 · 31 Mar 2006 · 8,292 accessesView PDFCite
Research ArticleOpen accessIn the abstractComparison of Probit and Logistic Regression Models in the Analysis of Dichotomous OutcomesAmrutha Jose, Mariyamma Philip, Lavanya Tumkur Prasanna, M. ManjulaProbit and logistic regression models are members of the family of generalized linear models, used for estimating the functional relationship between the dichotomous dependent and independent variables. The current study is designed to find the performance of logistic and probit regression models in different conditions under multivariate normality. The objective of the study is to compare the performance of probit … …Current Research in Biostatistics, Vol. 10, Issue 1 · 26 Mar 2020 · 17,036 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Relevance of Bioinformatic Tools in the Study of Polymorphisms of the B4GALNT2 Gene and its Association with CancerEddaikra Atika, Haddouche Hayet, Touil-Boukoffa ChafiaThe human gene B4GALNT2 encodes an enzyme (β1,4-N-acetylgalactosaminyltransferase II) that controls the expression of the blood group Sda carbohydrate’s antigen. This gene is located in position 17q21,32 and consists of 11 exons. The characterization and understanding of genetic variation is a real challenge in human genetics, both for healthy individuals and diseased ones. The in silico study of the B4GALNT2 … …Current Research in Bioinformatics, Vol. 8, Issue 1 · 27 Feb 2020 · 6,767 accessesView PDFCite