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61 results for “Response surface methodology”
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Research ArticleOpen accessIn the keywordsExtraction, Partial Identification and Bioactivities of Total Flavonoids from Carex meyeriana KunthHongbiao Wang, Penghui Wang, Xiudong Yang et al.To date, knowledge associated with extraction, chemical constituents and bioactivities of Total Flavonoids from Carex meyeriana Kunth (TFCMK) that remains unclear. Therefore, this paper was designed to optimize the ethanol reflux extraction method by response surface methodology and determine the chemical constituents by Liquid Phase-Mass Spectrometry (HPLC-MS); additionally, the bioactivities including antioxidant, antibacterial and hemolysis test were also explored. The … …American Journal of Biochemistry and Biotechnology, Vol. 15, Issue 3 · 7 Aug 2019 · 7,523 accessesView PDFCite
Research ArticleOpen accessIn the keywordsOptimization of Hydrolysis Conditions for Obtaining Antithrombotic Peptides from Tenebrio Molitor LarvaeFangyuan Chen, Han Jiang, Yini Gan et al.Tenebrio molitor larvae was hydrolyzed by pepsin and trypsin for preparing high antithrombotic activity hydrolysate. The significant variables were selected according to the Plackett-Burman design and further optimized by the Response Surface Methodology (RSM). Four factors, including substrate concentration, pepsin digestion time, pepsin amount and trypsin amount, respectively, influenced significantly on the hydrolysis effectiveness. The best hydrolysis conditions obtained using … …American Journal of Biochemistry and Biotechnology, Vol. 15, Issue 2 · 20 May 2019 · 8,722 accessesView PDFCite
Research ArticleOpen accessIn the keywordsResponse Surface Optimized Ultrasonic Assisted Extraction of Total Flavonoids from Walnut Leaves and In Vitro Antibacterial ActivitiesYuanda Song, Aydin Berenjian, Han Wu et al.In this paper, the optimum extraction conditions of total flavonoids extracted from walnut leaves subjected to Ultrasonic Assisted Extraction (UAE) were optimized by Response Surface Methodology (RSM). The mathematical model showed the high coefficient of measurement (R2 = 0.9938) which indicated that this model could be used to guide the response surface methodology. The optimum extraction parameters for extracting flavonoids … …American Journal of Biochemistry and Biotechnology, Vol. 13, Issue 4 · 24 Oct 2017 · 7,825 accessesView PDFCite
Research ArticleOpen accessIn the keywordsBiodegradation of 2, 4 DichlorophenolTaghreed Al-Khalid, Muftah H. El-NaasThe present study focuses on the optimization of process parameters of the aerobic biodegradation of 2, 4 Dichlorophenol (2, 4 DCP) by a commercial strain of P. putida immobilized in PVA gel matrix, using design of experiments by Response Surface Methodology (RSM). The degradation rates obtained from these experiments were used to evaluate the effects of the main factors and … …American Journal of Engineering and Applied Sciences, Vol. 10, Issue 1 · 12 Mar 2017 · 7,390 accessesView PDFCite
Research ArticleOpen accessIn the keywordsOptimization of Hydrolysis Conditions for the Production of Iron-Binding Peptides from Scad (Decapterus maruadsi) Processing ByproductsWenting Zhang, Yanan Li, Jie Zhang, Guangrong HuangThe scad (Decapterus maruadsi) processing byproduct (SPB) was hydrolyzed by four commercial enzymes, namely, trypsin, flavourzyme, protamex and alcalase, for preparing high Iron-Binding Capacity (IBC) hydrolysate. Alcalase was the best choice for obtaining high IBC hydrolysate from SPB. Response surface methodology using a central-composite design was employed to optimize the enzymatic hydrolysis conditions with alcalase to obtain a maximum hydrolysate … …American Journal of Biochemistry and Biotechnology, Vol. 12, Issue 4 · 17 Oct 2016 · 7,589 accessesView PDFCite
Research ArticleOpen accessIn the keywordsOptimization of Microwave-Assisted Extraction of a Bioherbicide from Canavalia ensiformis LeavesDarlan Ferreira Silva, Eduardo Bessa Azevedo, Maria Olímpia Oliveira RezendeThe objective of this study was to optimize the operational conditions of the Microwave-Assisted Extraction (MAE) of Canavalia ensiformis leaves by Response Surface Methodology (RSM), based on analysis of phenolic compounds obtained from the aqueous extracts. Optimal conditions for MAE were temperature of 100°C, extraction time of 10 min and ramp of temperature of 5 min, using approximately 2 g … …American Journal of Environmental Sciences, Vol. 12, Issue 1 · 29 Feb 2016 · 7,612 accessesView PDFCite
Research ArticleOpen accessIn the keywordsOptimization of a Combined Approach for the Treatment of Carbide Slurry and Capture of CO2Shereen Hasan, Muftah H. El-NaasThe aim of this study is to evaluate the potential use of electrocoagulation in the treatment of carbide slurry, a wastewater generated during the production of acetylene, and in the capture of carbon dioxide. An electrochemical batch reactor was used to carry out several experiments at different current densities, ranging between 140-290 A/m2. Pure air and a mixture of 10% … …American Journal of Engineering and Applied Sciences, Vol. 9, Issue 3 · 30 Dec 2015 · 7,988 accessesView PDFCite
Research ArticleOpen accessIn the keywordsModification Approach of Fuzzy Logic Model for Predicting of Cutting Force When Machining Nickel Based Hastelloy C-276Basim A. Khidhir, Bashir Mohamed, Mahmoud A.A. YounisProblem statement: Most Nickel based Hastelloy C-276 is a difficult-to-machine material because of its low thermal diffusive property and high strength at high temperature. Machinability consideration of nickel based Hastelloy C-276 in turning operations has been carried out using ceramic inserts under dry conditions. Approach: This study described a modification approach applied to a fuzzy logic based model for predicting … …American Journal of Engineering and Applied Sciences, Vol. 3, Issue 1 · 31 Mar 2010 · 8,456 accessesView PDFCite
Research ArticleOpen accessIn the keywordsModeling of Oxygen Transfer Correlations for Stirred Tank Bioreactor Agitated with Atypical Helical Ribbon ImpellerMohd Shamzi Mohamed, Rosfarizan Mohamad, Ramakrishnan Nagasundara Ramanan et al.Problem Statement: Mixing filamentous fungi entails delicate balance between promoting high volumetric oxygen transfer coefficient (kLa) while keeping low hydrodynamic stresses in the microenvironment of cultures. This study examined the oxygen transfer capability of a prototype low shear helical impeller as a potential replacement for the standard Rushton turbine. Approach: The dependence of kLa upon specific power uptake, superficial gas … …American Journal of Applied Sciences, Vol. 6, Issue 5 · 31 May 2009 · 9,167 accessesView PDFCite
Research ArticleOpen accessIn the keywordsAmphoteric Starch in Simultaneous Process Preparation with Box-Behnken Design for Optimal ConditionsSopa Cansee, Juntanee Uriyapongson, Commueng Watyotha et al.Cassava starch was chemically modified to produce an amphoteric starch. The amphoteric starch was prepared in a simultaneous process which was evaluated in relation to four factors: temperature (45-55 °C), 3-chloro-2-hydroxypropyltrimethylammonium chloride (CHPTAC, 4-12%) and sodium tripolyphosphate (STP, 2-8%) concentrations, and reaction time (2-6 h). The extent of amphoteric starch produced was determined by the degree of substitution (DS) of … …American Journal of Applied Sciences, Vol. 5, Issue 11 · 30 Nov 2008 · 7,523 accessesView PDFCite