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Research ArticleOpen accessIn the abstractEpigenetic Regulation of Extracellular Matrix Remodeling in Skin Aging: Mechanisms and InteractionsJiguang Yang, Yusong Shi, Xiaoqing YanSkin aging results from complex interactions between genetic factors, environmental stressors, and epigenetic modifications that regulate extracellular matrix (ECM) remodeling. Accumulation of senescent cells impairs tissue regeneration through mechanisms including telomere shortening, reactive oxygen species accumulation, and ultraviolet (UV) radiation exposure. While epigenetic pathways regulate skin homeostasis, regeneration, and senescence, the specific epigenetic changes occurring during UV exposure, chronological aging, … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 4 · 15 Feb 2026 · 1,458 accessesView PDFCite
Research ArticleOpen accessIn the abstractDifferential Expression of Cellular and Exosomal MicroRNA Isolated from Oral Cancer Cells and their Resistance to ChemotherapyBrady Petersen, Carl Yu, Samuel Hutchings et al.MicroRNAs are abundant small non-coding RNA with a variety of known functions, including transcriptional activation and inhibition. Recent evidence has suggested that microRNA expression may influence the responsiveness of some cancers to chemotherapy, including liver and lung cancers. Some evidence has now suggested that specific microRNAs, such as miR-21, miR-155, and miR-375, may influence oral cancer responsiveness to chemotherapy – … …Current Research in Dentistry, Vol. 13, Issue 1 · 29 Jul 2022 · 5,902 accessesView PDFCite
Research ArticleOpen accessIn the abstractGenetic Diversity of Leifsonia xyli Subsp. xyli Causing Ratoon Stunting Diseases of Sugarcane in Indonesia Using Intergenic Spacer Region Sequence AnalysisSisca Prayudani Usman, Abdul Latief Abadi et al.Leifsonia xyli subsp xyli (Lxx) is the cause of Ratoon Stunting Disease (RSD) on sugarcane and it considers as a quarantine pest in certain regions of Indonesia. RSD is a systemic disease that causes severe cane yield loss. Information about genetic diversity of this bacterial pathogen in Indonesia is limited. While global trading of sugar cane seed may facilitate the … …OnLine Journal of Biological Sciences, Vol. 25, Issue 2 · 23 Jun 2025 · 3,351 accessesView PDFCite
Review ArticleOpen accessIn the abstractSalt Tolerance and Cultivation Challenges of Jojoba (Simmondsia chinensis): A ReviewHeba Allah Adel MohassebJojoba is considered to be salt tolerant, but little is known about the extent of its tolerance and the relative influence on ion uptake and ethylene production and other factors are affecting the mode of actions of jojoba salt tolerant. According to many research has done before including our article about the glyoxalase I gene from jojoba which exhibits moderate … …OnLine Journal of Biological Sciences, Vol. 25, Issue 2 · 12 Jun 2025 · 3,314 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Impact of Climate Factors on the Epidemiology and Management of Potato virus YMahabuba Mostafa, Md. Motaher HossainPlant viruses give rise to potential loss to global crop production and have the potential to cause widespread damage. Potato virus Y (PVY) is a plant virus that belongs to the genus Potyvirus and the family Potyviridae and it is considered a major concern, particularly for solanaceous crops such as potatoes. PVY represents the largest cluster of plant viruses, encompassing … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 31 Aug 2024 · 4,758 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Cross-Sectional Study of the Prevalence of Hepatitis C Virus InfectionOmar Atrooz, Rehab Thunibat, Ihssan AtroozLiver pain is increased by hepatotropic viruses, such as the Hepatitis C Virus (HCV). This illness can progress to cirrhosis and hepatocellular cancer. This study aims to determine the prevalence of hepatitis C in the Southern Jordanian cities (Karak and Tafilah) as well as the correlations between alanine Aminotransferase (ALT), Aspartate aminotransferase (AST), age and gender in hepatitis C patients. … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 5 Jul 2024 · 4,414 accessesView PDFCite
Research ArticleOpen accessIn the abstractAlcohol Intubation and Synergistic Effect of Folic Acid and Egg Yolk Powder Solution on Alcohol Dehydrogenase [ADH] Class I Gene Expression and Single Nucleotide Polymorphism Frequency in Parent and Prenatal Alcohol Exposed Wistar RatsAdejoke Olukayode Obajuluwa, Oluyinka Ajibola Iyiola, Joseph Akintade Morakinyo et al.Point mutation detections in alcohol metabolizing genes could unravel molecular targets of gestational alcohol and epigenetic remodeling capacity of maternal nutrition, which underscores growth and health endpoints in Pre­natal Alcohol Exposed (PAE) fetuses. gene expression was assayed using sequenced target and internal control gene primers in a two-step thermal cycling process from isolated RNA in purely bred alcohol male and … …OnLine Journal of Biological Sciences, Vol. 24, Issue 1 · 22 Nov 2023 · 4,857 accessesView PDFCite
Research ArticleOpen accessIn the abstractUPLC-QTOF-MS/MS and Bioinformatics Association Analysis Reveals the Pharmacodynamic Flavonoids in Scutellaria barbata and the Underlying Anti-Colorectal Cancer MechanismYi-Jie Cheng, Xin-Yun Du et al.Colorectal Cancer (CRC) is one of the most common and deadly malignancies worldwide, with no safe and effective drugs. The flavonoid in Scutellaria Barbata D. Don (SB) showed a good therapeutic effect on CRC. However, the pharmacodynamic substances and underlying mechanisms have not been elucidated which limited its development and application. This study aimed to identify the main flavonoid in … …American Journal of Biochemistry and Biotechnology, Vol. 19, Issue 4 · 14 Nov 2023 · 5,398 accessesView PDFCite
Research ArticleOpen accessIn the abstractExpression of microRNA miR-27, miR-124 and miR-218 Among Dental Pulp Stem Cell (DPSC) IsolatesMark Whiting, Karl KingsleyDental Pulp Stem Cells (DPSCs) are non-embryonic, mesenchymal stem cells that may have significant potential for therapeutic and regenerative biomedical applications. MicroRNAs are small non-coding RNA molecules that can act as transcriptional activators and repressors in many types of mesenchymal stem cells. To date, few studies have evaluated the expression or activity of microRNAs among dental pulp stem cells. Using … …Current Research in Dentistry, Vol. 9, Issue 1 · 1 Jan 2019 · 8,167 accessesView PDFCite
Research ArticleOpen accessIn the abstractExpression of Metallothionein-Like Protein 2B Gene Induced by Different Concentrations of Copper in White Spruce (Picea glauca)Megan McKergow, Kabwe NkongoloThe alterations to the expressions of metal transporter genes can induce metal ion uptake to maintain cell homeostasis when metal concentrations are low. Metallothioneins (MTs) are a class of low molecular mass (4-8 kDa), cysteine (Cys)-rich proteins that can bind metals via the thiol groups of their Cys residues. Studies on MT gene expressions in higher plants, such as conifers, … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 4 · 25 Dec 2022 · 5,118 accessesView PDFCite