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121 results for “Male Rats”
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Research ArticleOpen accessIn the abstractIntravenous Injection of Umbilical Cord-Derived Mesenchymal Stem Cells Improved Regeneration of Rat Liver after 2AAF/CCl4-Induced InjuryIsabella Kurnia Liem, Reni Oktavina, Zakiyah et al.The effectivity of Mesenchymal Stem Cell (MSC) therapy for chronic liver injury is still questioned due to its possibility to have a pro-fibrotic effects. Other consideration is the preferably peripheral Intravenous (IV) route of application rather than direct to the target organ, such as portal vein or splenic vein, since the most of MSC will be trapped in the lung … …OnLine Journal of Biological Sciences, Vol. 21, Issue 2 · 10 Jun 2021 · 6,780 accessesView PDFCite
Research ArticleOpen accessIn the abstractProtective Effect of Lactoferrin against Chromium Induced Adverse Renal Changes in Rats: Oxidative Stress TheoryMohammed H. Hassan, Dorreia Abd-Alla Mohamed Zaghloul, Marwa Ahmed Mahmoud et al.Among the toxic metals, chromium (Cr) which is a naturally occurring heavy metal commonly enters the environment through the effluents from various industries. Kidney disease is often cited as an adverse effect of chromium. We aimed to assess chromium-induced pathophysiological adverse renal damage and determine the potential protective effects of co-therapy with Lactoferrin (LF) in male albino rats. Forty male … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 2 · 28 Apr 2021 · 6,663 accessesView PDFCite
Research ArticleOpen accessIn the abstractChronic and Acute Effect of Tramadol Intoxication on Some Immunological ParametersLoveday Udu Zebedee, Zaccheus Awortu Jeremiah, Nyebuchi Jonathan, Eni-Yimini Solomon AgoroTramadol intoxication is rapidly on the increase in Nigeria with unestablished short-term and long-term effects. The study was aimed at elucidating the dose-dependent effect of acute or chronic tramadol intoxication on some immunological parameters using male rats (Rattus norvegicus). A total of fifty adult rats were used for the study as indicated by Mead's Resource Equation. The study consisted of … …American Journal of Immunology, Vol. 17, Issue 1 · 24 Apr 2021 · 8,025 accessesView PDFCite
Research ArticleOpen accessIn the abstractAmphetamine Stimulates Protein Kinase and Calcium Influx to Increase Corticosterone and Aldosterone Secretion from Male Rat Adrenal CellsLing-Ling Chang, Wan-Song Alfred Wun, Cai-Yun Jian, Paulus S. WangAmphetamine is a potent central nervous system stimulant. Clinical trials have demonstrated that in healthy adults, low (therapeutic) doses of amphetamine can improve i.e., cognition, memory, attention behavior. An amphetamine overdose can affect cardiovascular, central nervous system, musculoskeletal, respiratory, urinary, or sexual function. Furthermore, amphetamine can activate the hypothalamic-pituitary-adrenal axis to increase glucocorticoids and mineralocorticoids released from adrenal. The object … …American Journal of Pharmacology and Toxicology, Vol. 16, Issue 1 · 10 Mar 2021 · 7,872 accessesView PDFCite
Research ArticleOpen accessIn the abstractHuman Adipose Stem Cells in Collagen on Angiogenesis Process of Burn Healing in Rat Model: Its Number of Blood VesselsLuluk Yunaini, Puji Sari, Dwi Pratami Septiara et al.Angiogenesis in the burn wound healing process is important. The application stem cell therapy in burn wound problem is expected to increase formation of new blood vessel so that the distribution of oxygen and nutrients working well. The purpose of this study was to known effect of human Adipose Derived Stem Cell (hADSC) in collagen gel on the average number … …OnLine Journal of Biological Sciences, Vol. 19, Issue 1 · 7 Jan 2019 · 7,600 accessesView PDFCite
Research ArticleOpen accessIn the abstractApplication of Human Adipose Stem Cell (hADSC) in Collagen Gel on Rat Deep Dermal BurnHelsy Junaidi, Puji Sari, Dwi Pratami Septiara et al.Human adipose derived stem cells (hADSC) is expected to be an efficient solution for healing deep-dermal burns that help in wound closure. This study used 20 male Sprague dawley rats. Each rat received three wounds with different treatments (control, hADSC in collagen gel and collagen gel). Wound closure was observed at day 7th, 14th, 21th and 28th (sacrificed day) macroscopically, … …OnLine Journal of Biological Sciences, Vol. 19, Issue 3 · 13 Sep 2019 · 7,604 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Influence of Garcinia kola Seed on Sexual Behavior and Testis Physiology in Wistar RatsJonah Sydney Aprioku, Victor Nwachukwu, Blessing Ukamaka Okeke et al.Garcina kola seed is believed by some to enhance male sexual performance but existing scientific data show divergent results. In this study, the sexual and reproductive influence of ethanol (70%) seed extract of G. kola was evaluated in Wistar rats. Adult male rats were gavaged with 0, 50, 100, 200 or 300 mg kg-1 day-1 of extract for 30 days … …American Journal of Pharmacology and Toxicology, Vol. 13, Issue 1 · 25 Apr 2018 · 13,804 accessesView PDFCite
Research ArticleOpen accessIn the abstractCarica papaya Fruit Attenuates Apoptotic Degeneration After Permanent Cerebral Ischemia RatPratchaya KaewkaenApoptotic neurodegeneration is a phenomenon following cerebral ischemia. Both the increased caspase-3 and decreased Bcl-2 expression are reported to play crucial role on apoptosis in neuron. In addition, phytonutrient can successfully increase the endogenous antioxidant and lower the apoptotic responses. Therefore, anti-apoptotic effect of Carica papaya fruits was examined. To the best of our knowledge, no scientific effect was available. … …American Journal of Biochemistry and Biotechnology, Vol. 14, Issue 4 · 22 Nov 2018 · 9,790 accessesView PDFCite
Research ArticleOpen accessIn the abstractGreen Tea Treatment Attenuates Oxidative Damage and Neuromotor Deficit Induced by an Experimental Model of Intracerebral Hemorrhage in RatsMauren Assis Souza, Caroline Dalla Colletta Altermann, Alexandre dos Santos Martins et al.The present study shows the neuroprotective effect of green tea supplementation (GT; Camellia sinensis) in a model of Intracerebral Hemorrhage (ICH) in rats. ICH was induced by intra-striatum collagenase infusion in male Wistar rats. GT (400 mg Kg-1) was administered via gavage for 10 days after ICH. We assessed the effect of GT on neuromotor recovery and oxidative damage. Our … …Neuroscience International, Vol. 7, Issue 2 · 19 Mar 2017 · 8,598 accessesView PDFCite
Research ArticleOpen accessIn the abstractPreventive Effect of Marsileacrenata Leaves and Stalks Juices Against Urolithiasis Showed by Improving of Kidney FunctionSri MurwaniNowadays urolithiasisis still as a major problem in pet animals, particularly for dogs and cats. Urolithiasisis caused by formation of crystals in the urinary tract that inhibit the process of urination. It is frequently as an impact of dry food given regularly, keeping animals in a place so that the movement of the animal becomes restricted, lack of water intake, … …American Journal of Animal and Veterinary Sciences, Vol. 11, Issue 1 · 10 Feb 2016 · 9,305 accessesView PDFCite