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100 results for “Inhibitory Activity”
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Literature ReviewOpen accessIn the abstractFundamental Questions about γδT CellsMoulay Yassine Belghali, Saadia Ba-M’hamed, Mouna Khouchani, Brahim AdmouγδT cells is a minor subgroup of T lymphocytes expressing γδ-T Cell Receptor (TCR), with many subsets, dominated by Vδ2 and Vδ1. γδT cells recognize antigens independently of the context of MHC class I, MHC class II, or CD1 presenting molecules. However, this recognition requires the expression of the transmembrane Butyrophilin proteins by the presenting cells. Their activation is controlled … …OnLine Journal of Biological Sciences, Vol. 20, Issue 4 · 15 Dec 2020 · 6,384 accessesView PDFCite
Research ArticleOpen accessIn the abstractPharmacological Properties of Bioactive Extracts from the Rhizome of Aristolochia longa LAmal El Hamsas El Youbi, Dalila BoustaAristolochia longa is a medicinal plant well known in Moroccan folk medicine for its activity against constipation, intestinal infections and skin diseases. The present study was performed to evaluate in vitro and in vivo immunomodulatory and cytotoxic activities of aqueous and protein extracts of A. longa. The in vitro immunomodulatory results showed that aqueous extract at 0.1 mg/mL enhanced T-lymphocyte … …American Journal of Pharmacology and Toxicology, Vol. 15, Issue 1 · 21 Jul 2020 · 7,459 accessesView PDFCite
Research ArticleOpen accessIn the abstractInhibitory Effect of Crude Walnut Leaf Polysaccharides on Oxidative Damage of Proteins and Proliferation of SGC-7901 CellsShuqing Yang, Zhike Xie, Shuyan Yu et al.In this paper, we studied the inhibitory effect of crude Walnut Leaf Polysaccharides (WLP) on free radical-induced oxidative damage of proteins and anti-proliferation activity on human Gastric Cancer cells (SGC-7901). The oxidative degradation of Bovine Serum Albumin (BSA), mouse brain proteins (MBP) and Mouse Liver Proteins (MLP) induced by hydroxyl radical and alcoxyl radical was analyzed by Sodium Dodecyl Sulfate-Polyacrylamide … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 2 · 26 Apr 2020 · 7,061 accessesView PDFCite
Research ArticleOpen accessIn the abstractQSAR Modeling of Thirty Active Compounds for the Inhibition of the Acetylcholinesterase EnzymeNour El Houda Hammoudi, Yacine Benguerba, Widad SobhiThis work aims at developing a reliable and predictive QSAR model which allows, on one hand, an exploration of the main molecular descriptors responsible for the inhibitory activity towards the Acetylcholinesterase enzyme and, on the other hand, predict the inhibitory activity of new compounds before testing them experimentally. This study involves a series of DL0410 and its 29 DL0410 derivatives. … …Current Research in Bioinformatics, Vol. 8, Issue 1 · 2 Mar 2020 · 11,431 accessesView PDFCite
Research ArticleOpen accessIn the abstractTotal Phenolic, Resveratrol Content, Antioxidant and Antimicrobial Activity in Five Cultivars of Peanut SproutsQing Liu, Shaoqi Li, Yao Zhang et al.Peanut sprout is one of the potential natural sources of bioactive substances. In this study, five different peanut cultivars were conducted to germination, the change in total phenolic compounds, resveratrol content, antioxidant and antimicrobial activity were investigated. The sprouts of five peanut cultivars (Fuhua, Silihong, Dabaisha, Xiaobaisha and Huayu) were extracted using 75% ethanol for 3 h and the crude … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 1 · 12 Feb 2020 · 8,555 accessesView PDFCite
Research ArticleOpen accessIn the abstractExtraction Optimization and Antibacterial Property of Total Flavonoids from Zizania Latifolia Bracts and the Effect on Chilled Pork PreservationChen Pan, Shuyi Zhu, Na Niu et al.Zizania latifolia isa widely distributed aquatic vegetable, and its bracts are an agriculturalwaste with a large proportion. In this study, Total Flavonoids of Z. latifoliaBracts (TFZB) were extracted with Ultrasound-Assisted Enzymatic Extraction(UAEE) for the first time, and the extraction process was optimized usingResponse Surface Method (RSM), and compared with other methods. Then, theantibacterial activity of TFZB extracted with optimized UAEE … …American Journal of Biochemistry and Biotechnology, Vol. 18, Issue 3 · 15 Sep 2022 · 6,013 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntileishmanial and Antibacterial Activity of Essential Oils of Medicinal Plant Achillea santolina L.Abdulkarim Dakah, Mohammed MaarroufAchillea santolina is medicinal plant widely used in folk medicine for gastrointestinal disorders, anti-inflammatory and anti-diuretic. The World Health Organization (WHO) reports that about 350 million people are considered to be at risk of contracting leishmaniasis especially among people living in the developing countries. This research will be the first time that evaluate antileishmanial activity of essential oils of A. … …OnLine Journal of Biological Sciences, Vol. 19, Issue 1 · 2 Mar 2019 · 9,202 accessesView PDFCite
Research ArticleOpen accessIn the abstractPreparation of Antimicrobial Collagen Casings with High Mechanical PropertiesZhike Xie, Shuyan Yu, Ming He et al.Tea Polyphenols (TP) has received much attention for their excellent antioxidant and antibacterial activities. Some additives (such as sodium alginate and sodium pyrophosphate) have good hydrophobicity which have influence on the mechanical properties of food. The effect of TP on the antibacterial activity of collagen casing was investigated, the effect of addition of TP, sodium pyrophosphate and sodium alginate on … …American Journal of Biochemistry and Biotechnology, Vol. 16, Issue 3 · 2 Sep 2020 · 6,629 accessesView PDFCite
Research ArticleOpen accessIn the abstractHighlight of New Phosphodiesterase 10A Inhibitors Using Molecular DockingHalla Belhoula, El Hassen Mokrani, Abderrahmane Bensegueni, Djihane BioudPhosphodiesterase 10A (PDE 10A) is an effective therapeutic approach for treatments of Schizophrenia (SCZ). In order to identify in silico new potent PDE 10A inhibitors, molecular docking approach was used. In this context, the compound S235 was predicted to exhibit a high potential PDE 10A inhibitory activity among 369 compounds tested. The predicted binding energy of this compound was improved … …Current Research in Bioinformatics, Vol. 8, Issue 1 · 27 Feb 2020 · 6,706 accessesView PDFCite
Research ArticleOpen accessIn the abstractBioactive Compounds from Sponge Associated Bacteria: Anticancer Activity and NRPS-PKS Gene Expression in Different Carbon SourcesJepri Agung Priyanto, Rika Indri Astuti, Jun Nomura, Aris Tri WahyudiSponge associated bacteria with diverse NRPS-PKS genes could be the alternative source of bioactive compounds. This study aimed to analyze the activity as well as the regulatory mechanism regarding the anticancer properties derived from these bacteria against cancer cell lines. Extraction of bacterial metabolites using ethyl acetate solvent resulted yield ranging from 0.003 to 0.016% (w/v). Six extracts of bacterial … …American Journal of Biochemistry and Biotechnology, Vol. 13, Issue 4 · 5 Oct 2017 · 8,891 accessesView PDFCite