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81 articles for “Exposure Time”
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Research ArticleOpen accessIn the abstractCytotoxicity Studies of Superparamagnetic Iron Oxide Nanoparticles in Macrophage and Liver CellsAroonsri Priprem, Pramote Mahakunakorn, Chunpen Thomas, Ian ThomasSuperparamagnetic Iron Oxide Nanoparticles (SPIONs) prepared by simplified coprecipitation were attractive as MRI contrast agents and drug carriers which could internally be manipulated under the influence of an external magnetic field and also cancer treatment due to additional hyperthermia effects. Problem statement: Macrophage and liver cells are potentially exposed to internal SPIONs, thus used for this cytotoxic tests for safety … …Current Research in Nanotechnology, Vol. 1, Issue 2 · 22 Jun 2011 · 11,629 accessesView PDFCite
Research ArticleOpen accessIn the abstractBonding Property of Bituminous Crack Sealants in the Presence of WaterEllie Fini, Taher Abu-LebdehProblem statement: Crack sealing and filling is the most widely used maintenance activity for in-service pavements. If an appropriate sealant material is selected and properly installed at the appropriate time of the pavement life, it retards pavement deterioration and increases its service life at a relatively low cost. However, in some cases it is reported that sealants failed prematurely, mainly … …American Journal of Engineering and Applied Sciences, Vol. 4, Issue 1 · 12 Mar 2011 · 8,348 accessesView PDFCite
Research ArticleOpen accessIn the abstractPhotostability of Ponceau 2R Doped Thin Film Sol-Gel Silica as Luminescent Solar CollectorS.M. RedaProblem statement: Current researches had shown that the photostability of a luminescent solar collector depend on the method of its preparation and type of using dye. This research therefore aimed at studying the stability of luminescent solar collector prepared by sol-gel spin coating method using Ponceau 2R. Approach: The effect of silica matrix on the photostability and fluorescence properties of … …Energy Research Journal, Vol. 1, Issue 1 · 30 Jun 2010 · 7,224 accessesView PDFCite
Research ArticleOpen accessIn the abstractDifferential Gene Expression in Zebrafish (Danio rerio) Following Exposure to Gaseous Diffusion Plant Effluent and Effluent Receiving Stream WaterBen F. Brammell, Andrew J. WiggintonProblem statement: The expression of six genes known to serve as bioindicators of environmental stress were examined using real-time quantitative PCR in liver tissue extracted from zebrafish (Danio rerio, Hamilton) exposed to effluent and effluent containing stream water associated with the Paducah Gaseous Diffusion Plant (PGDP). Approach: The PGDP, the only active uranium enrichment facility in the US, is located … …American Journal of Environmental Sciences, Vol. 6, Issue 3 · 30 Jun 2010 · 7,775 accessesView PDFCite
Research ArticleOpen accessIn the abstractAssessing Community Health Risks: Proactive Vs Reactive SamplingSarah Taylor, Chelsea Papadopoulos, Sarah Vieillet, Peter Di MarcoProblem statement: A considerable number of native birds died in the West Australian coastal town of Esperance and surroundings during late 2006 and early 2007, which raised community concerns about environmental contamination. Forensic investigations of dead birds suggested that lead may have been the causative agent. At the time, lead and nickel, as well as iron ore and other materials, … …American Journal of Environmental Sciences, Vol. 5, Issue 6 · 31 Dec 2009 · 6,845 accessesView PDFCite
Research ArticleOpen accessIn the abstractP-Glycoprotein-Mediated Efflux and Drug Sequestration in Lysosomes Confer Advantages of K562 Multidrug Resistance Sublines to Survive Prolonged Exposure to Cytotoxic AgentsNathupakorn Dechsupa, Samlee MankhetkornProblem statement: Cellular drug resistance to anticancer agents is major obstacle in cancer chemotherapy and the mechanisms by which these MDR cells possess for protecting themselves to survive prolonged exposure to cytotoxic agents still debating. The study aimed to clarify the role of P-glycoprotein (Pgp) and enhanced drug sequestration in lysosomes to confer the multidrug resistance K562 cells with varied … …American Journal of Applied Sciences, Vol. 6, Issue 9 · 30 Sep 2009 · 7,508 accessesView PDFCite
Research ArticleOpen accessIn the abstractMountain Sheep: An Environmental Epidemiological Survey of Variation in Metal Exposure and Physiological Biomarkers Following Mine DevelopmentLawrence K. Duffy, Michael W. Oehler, R. Terry Bowyer, Vernon C. BleichProblem Statement: Anthropogenic activities, such as mining and industrial operations, are a major environmental source of metal exposure for wildlife. Quantitative data regarding biochemical effects of exposure to mineral extraction on mountain sheep, Ovis canadensis, are limited, although their habitats are becoming increasingly affected by expanded resource development. Decisions relating to environmental protection and wildlife conservation should be based on … …American Journal of Environmental Sciences, Vol. 5, Issue 3 · 30 Jun 2009 · 6,656 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of γ- ray, Microwave Heating and Solar Irradiation of Apple Juice on Organochlorinated Pesticides ResiduesK. Al-Ismail, S. Herzallah, H. DmoorThis study was conducted to evaluate the effect of solar radiation, microwave heating and γ-irradiation on the Organochlorinated Pesticide (OCP’s) in apple juice. The solar radiation caused a destruction of 20% after 20 hr exposure to sunlight compared to 12% reduction for the tested OCP’s after microwave heating for 10 min. On the other hand, the use of γ-irradiation leads … …American Journal of Agricultural and Biological Sciences, Vol. 4, Issue 1 · 31 Mar 2009 · 8,165 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Mathematical Modeling Approach to Characterize Hormesis, Caloric Restriction and Toxicity in Mortality Data from Toxicity StudiesPatricia J. NeafseyThe mortality of a population reflects the combined effects of natural aging with environmental insults (e.g. toxicant exposure, caloric restriction, over feeding, infections, etc.). No single endpoint, such as carcinogenesis, completely describes toxicant-induced effects in laboratory animals. Mathematical models of mortality and time-dependent exposure to toxicants can yield indices of net injury from all causes. With careful manipulation of diet … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 7,163 accessesView PDFCite
Research ArticleOpen accessIn the abstractAT1-IR-beta Association: A New Mechanism for the Inhibition of Insulin Receptor Function in Breast CancerLakshmi Pulakat, Ravindra Kolhe, Nara GaviniEpidemiological evidence show that increased mortality in breast cancer is linked to hypertension and insulin resistance. Because Angiotensin II (Ang II), a hormone implicated in hypertension and insulin resistance, is a normal mitogen for breast tissue and elevated expression of the Ang II receptor AT1 is seen in breast cancer, we analyzed the effects of Ang II exposure on the … …American Journal of Biochemistry and Biotechnology, Vol. 4, Issue 1 · 31 Mar 2008 · 7,019 accessesView PDFCite