Sign inSubmit
Tips: “quotes” for a phrase · author:Lee · a DOI goes straight to its article

97 results for “Dose Dependent”
Set a search alert
Research ArticleOpen accessIn the abstractTHE EFFECTS OF ORAL ADMINISTRATION OF DIFFERENT DOSES OF HYDROALCOHOLIC EXTRACT OF SILYMARIN ON STATUS OF SERUM TRACE ELEMENTSJ. Sajedianfard, S. Nazifi, H. A. ShamsaeiIn this research, the effect of oral administration of different doses of hydroalcoholic extract of silymarin on the status of trace elements with antioxidant properties (Se, Cu, Zn, Mn and Fe) was studied. Fifty male rats were randomly used in five groups including healthy control group (treated by saline), diabetic control group (treated by saline) and three diabetic groups that … …American Journal of Animal and Veterinary Sciences, Vol. 9, Issue 3 · 24 Oct 2014 · 6,646 accessesView PDFCite
Research ArticleOpen accessIn the abstractEXPOSURE TO SWINE HOUSING DUST MODULATES MACROPHAGE MORPHOLOGY AND FUNCTIONRuth J. Pender, Radiah C. Minor, Steven L. Hurley et al.Swine Confinement Facility (SCF) dust consists of a complex mixture of feed grain particles, bacterial components, organic particulates and gases. When these particles are inhaled they deposit along the respiratory tract and mediate respiratory symptoms and disease in swine farmers and facility workers. Macrophages ingest and eliminate microbes and debris under chronic conditions; however, the role of macrophages in agricultural-related … …American Journal of Immunology, Vol. 10, Issue 1 · 25 Mar 2014 · 7,609 accessesView PDFCite
Research ArticleOpen accessIn the abstractAMELIORATIVE EFFECT OF HIBISCUS SABDARIFFA LINN ON SUBCHRONIC CHLORPYRIFOS-INDUCED ALTERATIONS IN SEX AND THYROID HORMONES IN MALE WISTAR RATSShittu Muftau, Olatunji Omobolanle Aisha, Suleiman Folorunsho Ambali et al.Studies have shown that Chlorpyrifos (CPF), an Organophosphate (OP) insecticide alters both sex and thyroid hormones. Apart from inhibiting Acetylcholinesterase (AChE) activity, CPF has been shown to cause oxidative stress. The antioxidant potentials of many flavonoid-containing plants are increasingly being exploited in the therapy of many infectious and non-infectious diseases. Hibiscus Sabdariffa (HS) is one of the most widely used … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 1 · 20 Feb 2014 · 9,102 accessesView PDFCite
Research ArticleOpen accessIn the abstractEthanolic Extract of Leaves of Newbouldia laevis Attenuates Glycosylation of Hemoglobin and Lipid Peroxidation in Diabetic RatsKolawole O. Timothy, Akanji M. Adewumi, Awe O. Emmanuel, Akiibinu M. OlayemiDiabetes is one of the major health problems around the world and the incidence of this metabolic disorder is on the increase. Current therapeutic interventions have not done much in preventing complications of diabetes. Therefore this study investigated the effect of ethanolic extract of Newbouldia laevis leaves (NLet) on lipid peroxidation and glycosylation of hemoglobin, which are pathological indicators of … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 4 · 13 Nov 2013 · 8,126 accessesView PDFCite
Research ArticleOpen accessIn the abstractAdaptogenic Potentials of Cyphostemma glaucophilla Aqueous Leaf ExtractOjogbane Eleojo, Nwodo Okwesili Fred Chiletugo, Omale JamesCytophostemma glaucophilla aqueous extract is used in Kogi and Kwara States of Nigeria to treat Kwashiorkor and to boost immunity. As part of the effort to evaluate its effect on stress, it was screened for adaptogenic potentials. This investigation was conducted using albino rats to determine the ability of this plant to increase non specific resistance against physical, biological and … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 3 · 4 Sep 2013 · 7,124 accessesView PDFCite
Research ArticleOpen accessIn the abstractImmunomodulatory Activity of Argan Oil (Argania spinosa L)Youcef Necib, Ahlem Bahi, Sakina Zerizer et al.Immunomodulatory activity of Argan oil was evaluated on phagocytic activity by carbon clearance test. Adult Albinos Wistar rats randomly divided into four groups, were the first was served as a control, while animals of treatment group were given Argan oil at dose of: 2.5, 5 and 10 mL kg-1 by gavage respectively 10 days before injected the carbon ink suspension. … …American Journal of Immunology, Vol. 9, Issue 3 · 20 Aug 2013 · 6,935 accessesView PDFCite
Research ArticleOpen accessIn the abstractAroclor 1254 Toxicity to Mice Liver Membrane AtpasesShweta Pathak, Rahul KunduPresent communication reports the sub-acute dose and exposure duration dependent effects of Aroclor 1254 on total, Na+, K+, Ca++ and Mg++-ATPases of the mouse liver cells. The study tests two hypotheses, (a) whether the sublethal dose or the exposure duration dependent in vivo exposure of hydrophobic PCB (Aroclor 1254) affects the hydrophilic membrane-bound ion dependent ATPases of the liver cells … …American Journal of Pharmacology and Toxicology, Vol. 8, Issue 2 · 13 Jul 2013 · 6,795 accessesView PDFCite
Research ArticleOpen accessIn the abstractDiphenylhydantoin Promotes Proliferation in The Subventricular Zone and Dentate GyrusAlma Y. Galvez-Contreras, Rocio E. Gonzalez-Castaneda, Sonia Luquin et al.Problem statement: Diphenylhydantoin (phenytoin) is an antiepileptic drug that generates hyperplasia in some tissue by stimulating Epidermal Growth Factor (EGFR) and Platelet-Derived Growth Factor beta (PDGFR-β) receptors and by increasing serum levels of basic fibroblast growth factor (bFGF, FGF2 or FGF-β). Neural stem cells in the adult brain have been isolated from three regions: the Subventricular Zone (SVZ) lining the … …Neuroscience International, Vol. 3, Issue 1 · 6 Mar 2012 · 9,141 accessesView PDFCite
Research ArticleOpen accessIn the abstractZinc Phosphide Induced DNA Damage in the Blood Cells of Gallus sp. using Comet DNA AssayK. A. Muid, R. M. Shahjahan, R. Begum, R. A. BegumProblem statement: The comet DNA assay is considered a suitable and rapid test for DNA-damaging potential in environmental and biomonitoring studies. Approach: During the study comets were analyzed as a measure of DNA damage to quantify the damage in the blood cells of fowls (Gallus sp.) after exposure to Zinc Phosphide (Zn3P2). Here the potential for DNA strand breaks by … …American Journal of Agricultural and Biological Sciences, Vol. 7, Issue 1 · 3 Mar 2012 · 8,957 accessesView PDFCite
Research ArticleOpen accessIn the abstractIn Silico, In Vitro and In Vivo Assessment of Safety and Anti-inflammatory Activity of CurcuminM. Venkata, R. Sripathy, D. Anjana et al.Problem statement: Curcumin the active component of turmeric is known for its wide biological actions. Extensive studies on curcumin highlighted its anti-inflammatory, anti-oxidant, anti-microbial, anti-carcinogenic and anti-coagulant activity. The anti-inflammatory activities of curcumin have been demonstrated both in vitro and in vivo. Though curcumin and its anti-inflammatory properties are well documented, the exact mechanism of action and effective in vivo … …American Journal of Infectious Diseases, Vol. 8, Issue 1 · 23 Feb 2012 · 9,006 accessesView PDFCite