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143 results for “Cell model”
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EditorialOpen accessIn the abstractFocalize the Structure of Myd88 in TLR Signaling Pathway to Modulate Innate Immune Response: New Target for Old DiseasesShuai Xing, Ping ZhouAll diseases have their Achilles’ Heel to target and this is especially true for immunorelated diseases which must be treated by targeting the immune system somewhere and somehow correctly. In the most recent decade, immunologists recognized that the Toll-Like Receptor (TLR) signaling pathway in innate immune system plays a double-edged role in the pathogenesis of many notorious diseases. Although the … …American Journal of Immunology, Vol. 13, Issue 3 · 6 Sep 2017 · 7,862 accessesView PDFCite
Research ArticleOpen accessIn the abstractA New Approach to Model Concentrating PV Cells Under Non-Uniform IlluminationHang Zhou, Yuehong Su, Gang Pei et al.Concentrating PV (CPV) cells are often designed optimally depending on solar concentrator characteristics and operating conditions to ensure the best system performance. Before reaching a PV cell, solar radiation may experience some optical losses caused by the different physical phenomena occurring in a solar concentrator. A particular issue with the CPV technology is the non-uniformity of the concentrated radiation, which … …Energy Research Journal, Vol. 8, Issue 2 · 30 Aug 2017 · 7,137 accessesView PDFCite
EditorialOpen accessIn the abstractIs Rerum® the New Coley's Vaccine?Marco RuggieroColey's Vaccine and Cancer Immunotherapy Dr. William B. Coley is credited for having been the first to translate the observation of an association between bacterial infections, high fever and cancer remission into a successful cancer treatment. However, it is worth noting that such an association dates back to at least one century before Coley's times; as Wiemann and Starnes from … …American Journal of Immunology, Vol. 13, Issue 2 · 31 May 2017 · 12,281 accessesView PDFCite
Research ArticleOpen accessIn the abstractDesign of a Low Power and High Speed Comparator using MUX based Full Adder Cell for Mobile CommunicationsG. Ramana Murthy, Ajay Kumar Singh, P. Velraj Kumar, Tan Wee Xin WilsonThis paper presents an implementation of comparator (1-bit) circuit using a MUX-6T based adder cell. MUX-6T full adder cell is designed with a combination of multiplexing control input and Boolean identities. The proposed comparator design features higher computing speed and lower energy consumption due to the efficient MUX-6T adder cell. The design adopts multiplexing technique with control input to alleviate … …American Journal of Applied Sciences, Vol. 14, Issue 1 · 16 Jan 2017 · 8,251 accessesView PDFCite
Research ArticleOpen accessIn the abstractSeparation, Purification and Anti-aging Activity of Tobacco PolysaccharidesMengyue Huang, Jingwu Song, Shuaishuai Chang et al.To separate tobacco polysaccharides and investigate their antioxidant and anti-aging properties, crude tobacco polysaccharides were extracted from raw tobacco using hot water, followed by purification through DEAE-52 cellulose column chromatography. The molecular weight and monosaccharide composition of the isolated polysaccharides were analyzed using HPGPC and HPLC. The antioxidant activities of these tobacco polysaccharides were tested using DPPH, ABTS, hydroxyl radicals … …American Journal of Biochemistry and Biotechnology, Vol. 21, Issue 1 · 15 Jan 2025 · 5,103 accessesView PDFCite
Research ArticleOpen accessIn the abstractPotential of HMEC-1 Line and HUVEC Primary Culture Cells to Study the Neonatal IgG Fc Receptor in vitroLuz Belinda Ortiz-Alegría, Irma Cañedo-Solares, Felipe Vadillo-Ortega et al.The neonatal IgG Fc receptor (FcRn) plays an important role in IgG homeostasis and immunity passive transfer. Fine points regarding these mechanisms, however, are still emerging. In order to obtain information about these phenomena, it is essential to have in vitro models of endothelium that express this receptor. In this study we chose two widely used models of human endothelial … …American Journal of Immunology, Vol. 12, Issue 1 · 21 Mar 2016 · 9,446 accessesView PDFCite
Research ArticleOpen accessIn the abstractDetermination of Predictors Associated With HIV/AIDS Patients on ART Using Accelerated Failure Time Model for Interval Censored Survival DataPrafulla Kumar Swain, Gurprit GroverThe main objective of this paper is to identify the independent predictors affecting the survival of HIV/AIDS infected patients on Antiretroviral Therapy (ART), an interval censored event time outcome. A total of 2052 HIV/AIDS patients, who were on ART at Ram ManoharLohia Hospital, New Delhi, India, during the period of April 2004 to December 2010, were included for analysis. Accelerated … …Current Research in Biostatistics, Vol. 6, Issue 1 · 12 Jan 2016 · 8,311 accessesView PDFCite
EditorialOpen accessIn the abstractAre we Able to Harness the Immunomodulatory Power of Cytokines for Novel Autoimmune Disease Treatments?Giuseppe Nocentini, Graziella Migliorati, Carlo RiccardiSince the end of the 1970s, interleukin 2 (IL-2) has been known as a key player in T cell expansion/activation (Watson et al., 1980). In the late 1980s, some groups used IL-2 to stimulate the immune systems of tumour patients (Jacobs et al., 1986). The idea seemed brilliant and several attempts were made, but the results were disappointing (Lim et … …American Journal of Pharmacology and Toxicology, Vol. 10, Issue 2 · 22 Oct 2015 · 7,625 accessesView PDFCite
Research ArticleOpen accessIn the abstractControl of Incoming H2/O2 Flows in a PEM Fuel CellDhia Mzoughi, Nabila Khili, Hatem Allagui, Abdelkader MamiIt has become crucial, with the dwindling of energy resources related to the depletion risk of fossil and fissile resources, to find energy alternatives which have the same properties as those of a hydrocarbon in terms of transport and storage. In this context, the fuel cell appears as a very serious element both at the industrial and research levels. The … …American Journal of Applied Sciences, Vol. 12, Issue 1 · 26 Feb 2015 · 7,276 accessesView PDFCite
EditorialOpen accessIn the abstractNeutrophil Extracellular Traps as Therapeutic Targets for Inflammatory DiseaseRory R. KoenenNeutrophilic granulocytes, or neutrophils are the most abundant circulating white blood cell and constitute a first line of defense against pathogens. They are characterized by a large polymorphic lobular nucleus and the presence of many secretory granules in their cytoplasm. Neutrophils are essential for a functional host defense, as is evidenced by the occurrence of severe infections in individuals with … …American Journal of Pharmacology and Toxicology, Vol. 9, Issue 4 · 25 Feb 2015 · 8,737 accessesView PDFCite