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41 articles for “Cardiovascular system”
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Research ArticleOpen accessIn the abstractRole of Galphaq Containing Protein in Immune RegulationYuan Liu, Lu Gan, Guixiu ShiG proteins, one of the most important transmembrane signal transducers, contain four subfamilies. Gαq is the α subunit of Gq protein subfamily. The Gαq containing protein initially attracted attention for its physiological significance is in cardiovascular system. In recent years, its role in immune regulation has been indicated. Studies domenstrated that Gαq plays crucial role in regulating both innate and … …American Journal of Immunology, Vol. 8, Issue 4 · 18 Oct 2012 · 7,417 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Niacin on Hyperleptinemia and Ob Gene mRNA Over-Expression in Adipose Tissue of Dexamethasone Treated RatsTahoora Shomali, Mahnaz Taherianfard, Mehdi Fazeli, Niloofar SafaeiProblem statement: Glucocorticoid-induced ob gene over-expression and resulted hyperleptinemia may lead to adverse consequences especially on cardiovascular system; therefore, the present study was conducted to evaluate the effects of niacin on hyperleptinemia and ob gene over-expression due to dexamethasone administration in rats. Approach: Twenty four adult male rats divided randomly into four equal groups: 1- normal saline (control), 2- dexamathasone … …American Journal of Pharmacology and Toxicology, Vol. 6, Issue 2 · 17 Aug 2011 · 7,988 accessesView PDFCite
Research ArticleOpen accessIn the abstractAlmond Consumption Decreases Fasting and Post Prandial Blood Glucose Level in Female Type 2 Diabetes SubjectParul Choudhary, Saroj Kothari, Vimal SharmaProblem statement: Population studies indicate that individuals who regularly consume nuts have reduced risk for cardiovascular diseases and diabetes. The beneficial role of almonds has been established with respect to serum lipid profile however, its beneficial effects on glycemia is still to be established. Aim of the study was to investigate the response of almond feeding on fasting and post … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 8,092 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of the Severity of Mitral Valvular Regurgitation with Doppler Echocardiography Using Proximal Flow Convergence MethodPinjari Abdul Khayum, M.N. Giriprasad, P.V. SrideviProblem statement: Valvular regurgitation is recognized as the central cause of morbidity and mortality. Even though the clinician can detect the presence of regurgitation by mere physical examination; diagnostic methods become inevitable while estimating the severity of valvular regurgitation and in the transformation of cardiac chambers as in reaction to the volume overload condition. Lately, a promising new technology, the … …Journal of Computer Science, Vol. 5, Issue 2 · 28 Feb 2009 · 7,220 accessesView PDFCite
Research ArticleOpen accessIn the abstractγ-Aninobutyric acid (GABA) suppresses antigen-specific immune responses in ovalbumin γ(OVA)-immunized BALB/c miceTohru Sakai, Hiroko Okada, Mitsuo Kise et al.γ-Aminobutruic acid (GABA) is known to be a ubiquitous inhibitory neurotransmitter in the central nervous system. Furthermore, recent studies have shown that GABA modulates cardiovascular and respiratory functions. In this study, we examined the effect of GABA on antigen (Ag)-specific immune responses and elucidated the mechanisms underlying those effects in ovalbumin (OVA)-immunized BALB/c mice. OVA-specific proliferative responses were decreased in … …American Journal of Immunology, Vol. 1, Issue 3 · 30 Sep 2005 · 6,501 accessesView PDFCite
Research ArticleOpen accessIn the abstractVariability in Antihypertensive Drug Therapy and Compliance: Results from a Random Survey in the United Arab EmiratesSyed Azhar Syed Sulaiman, Muaed Jamal Alomar, Claire Caroline StrauchProblem statement: Hypertension is one of the most common diseases known as the ‘silent killer’ because it shows no clinical signs and symptoms. The high prevalence of hypertension in the United Arab Emirates stresses the importance to initiate a nation-wide effort to prevent and control high blood pressure in the population, especially since the prevalence rates are indicative of one … …American Journal of Pharmacology and Toxicology, Vol. 4, Issue 3 · 30 Sep 2009 · 7,230 accessesView PDFCite
Research ArticleOpen accessIn the abstractFour Dimensional (4-D) BioChemInfoPhysics Models of Cardiac Cellular and Sub-Cellular Vibrations (Oscillations)Kang Cheng, Chang-Hua ZouProblem statement: Cardiovascular Diseases (CVD) continued to be the leading cause of death. Failure or abnormal cardiac cellular or sub-cellular vibrations (oscillations) could lead failure or abnormal heart beats that could cause CVD. Understanding the mechanisms of the vibrations (oscillations) could help to prevent or to treat the diseases. Scientists have studied the mechanisms for more than 100 years. To … …OnLine Journal of Biological Sciences, Vol. 9, Issue 2 · 15 Jun 2009 · 7,057 accessesView PDFCite
Research ArticleOpen accessIn the abstractHormetic Triggers for Intervention in Aging, Disease and TraumaJoan Smith SonnebornHormesis refers to the ability of a chemical or physical agent to condition the physiological state of an organism to tolerate stress with low doses of otherwise harmful agents. Evolutionary evidence shows that the survival and longevity of species hinge on their optimal ability to resist stress challenge. Hormesis is a potent strategy to stimulate latent repair processes to tolerate … …American Journal of Pharmacology and Toxicology, Vol. 3, Issue 1 · 31 Mar 2008 · 7,895 accessesView PDFCite
Review ArticleOpen accessAll words, across the recordCoenzyme Q10 Supplementation Effect on Systemic DiseasesAya Jabbar HusseinThis review paper aims to examine recent RandomizedClinical Trials (RCTs) and review articles evaluating the role of CoQ10 in themanagement of atherosclerosis, and coronary heart disease, with particularfocus on Statin-Associated Muscle Symptoms (SAMS), chronic heart failure, andthe effect on cardiovascular risk factors. With an evaluation of its impacts onpatients' well‐being, it seeks to outline the existing opportunities for usingCoQ10 in … …American Journal of Pharmacology and Toxicology, Vol. 17, Issue 1 · 20 Oct 2022 · 6,525 accessesView PDFCite
Review ArticleOpen accessAll words, across the recordObesity as a Predisposing Factor for AtherosclerosisAnastasia Vladimirovna Poznyak, Victoria Alexandrovna Khotina et al.Obesity stands as a pressing global health concern, associated with a myriad of threats to human well-being and longevity. Within the scope of this review, we zero in on how obesity impacts the onset of atherosclerosis, given its well-established link as a risk factor in its development. The progression of atherosclerosis is notably hastened by obesity, driven by a host … …OnLine Journal of Biological Sciences, Vol. 25, Issue 2 · 23 Jul 2025 · 2,737 accessesView PDFCite