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114 results for “Cardiovascular Disease”
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Review ArticleOpen accessIn the keywordsOverview of Vascular Smooth Muscle Cells, Endothelial Cells, and Macrophages Apoptosis During Atherosclerosis DevelopmentAnastasia Vladimirovna Poznyak, Varvara Alexandrovna Orekhova, Vasily Nikolaevich Sukhorukov et al.Atherosclerosis is a complex disease that has garnered significant attention from researchers studying its various aspects. Its pathogenesis involves a wide array of cellular and molecular components, as well as crucial mechanisms and processes crucial for cellular and organismal functioning. Atherosclerosis is considered a chronic inflammatory disease characterized by disrupted lipid metabolism, oxidative stress, and immune response. Apoptosis, a fundamental … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 5 Jul 2024 · 4,677 accessesView PDFCite
Review ArticleOpen accessIn the keywordsSubfractions of Low-Density-Lipoprotein: Which is the Most Atherogenic?Anastasia Vladimirovna Poznyak, Vasily Nikolaevich Sukhorukov, Mikhail Аleksandrovich Popov et al.Atherosclerosis is a widespread disease of the arteries, which manifests itself in the narrowing of the lumen of the vessel due to the formation of plaque on its walls. Despite an impressive history of study, atherosclerosis still leaves room for researchers. This is realized due to the complexity of pathogenesis, in which important roles are assigned to a variety of … …OnLine Journal of Biological Sciences, Vol. 23, Issue 4 · 3 Sep 2023 · 4,706 accessesView PDFCite
Review ArticleOpen accessIn the keywordsObesity as a Predisposing Factor for AtherosclerosisAnastasia Vladimirovna Poznyak, Victoria Alexandrovna Khotina et al.Obesity stands as a pressing global health concern, associated with a myriad of threats to human well-being and longevity. Within the scope of this review, we zero in on how obesity impacts the onset of atherosclerosis, given its well-established link as a risk factor in its development. The progression of atherosclerosis is notably hastened by obesity, driven by a host … …OnLine Journal of Biological Sciences, Vol. 25, Issue 2 · 23 Jul 2025 · 2,742 accessesView PDFCite
Research ArticleOpen accessIn the keywordsAssociation Between Particulate Matter (PM10) Exposure and Cardiorespiratory Hospital Admissions: A Time Series AnalysisNur Nabila Abd Rahim, Abqariyah Yahya, Wan Rozita Wan MahiyuddinThis study aimed to evaluate the association between particulate matter (PM10) exposure and cardiorespiratory hospital admissions and develop a time series model for cardiorespiratory hospital admissions in Johor, Malaysia. Retrospective time series analysis was utilised to study cardiorespiratory hospital admissions for the study period 2015-2016. Over-dispersed Poisson generalized linear models with parametric smoothing functions were used to examine the association … …American Journal of Environmental Sciences, Vol. 17, Issue 2 · 27 May 2021 · 6,921 accessesView PDFCite
Review ArticleOpen accessIn the keywordsCardiolipin in Pathology: Implications in AtherosclerosisAnastasia Vladimirovna Poznyak, Vasily Nikolaevich Sukhorukov, Anton Yuvenalievich Postnov et al.Mitochondria are cell organelles whose main role is to generate the energy needed for cell biochemical reactions via oxidative phosphorylation. Cardiolipin is a phospholipid that is present in the inner mitochondrial membrane and other energy-transducing membranes. Mitochondrial structure largely depends on cardiolipin, as it is involved in the biogenesis of mitochondrial cristae, folds in the inner mitochondrial membrane designed to … …OnLine Journal of Biological Sciences, Vol. 23, Issue 4 · 23 Sep 2023 · 4,794 accessesView PDFCite
Research ArticleOpen accessIn the keywordsDietary Fats and Heart Disease: From Prenatal to Postnatal EnvironmentSukhinder K. CheemaProblem statement: Heart disease is the leading cause of death worldwide and is dramatically increasing in developing countries. Preventive approaches, such as dietary and lifestyle changes can have major health implications to prevent the onset of heart disease. Besides healthy nutrition in the adult life, maternal nutrition during pregnancy and lactation can also have a significant impact on the outcome … …Current Research in Medicine, Vol. 3, Issue 2 · 10 Aug 2012 · 7,437 accessesView PDFCite
Research ArticleOpen accessIn the keywordsMyocardial Motion Analysis of Echocardiography Images using Optical Flow Radial Direction DistributionSlamet Riyadi, Mohd Marzuki Mustafa, Aini HussainProblem statement: Myocardial motion is important information for physicians in diagnosing cardiac abnormalities. The motion vector of myocardial can be computed using optical flow technique, which then can be further analyzed based on its magnitude and angle. In practice, physicians are not concern about the angle of vector itself, but are more interested on whether a segment is moving to … …Journal of Computer Science, Vol. 7, Issue 7 · 28 Jun 2011 · 6,637 accessesView PDFCite
Review ArticleOpen accessIn the abstractJAK Inhibitors for Rheumatoid Arthritis: Assessing Efficacy and Safety in TreatmentAnastasia V. Poznyak, Varvara A Orekhova, Natalia Vladimirovna Elizova et al.Rheumatoid Arthritis (RA) is a chronic autoimmune disease characterized by synovial inflammation, progressive joint destruction, and systemic complications. Dysregulated cytokine signaling through the Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway plays a central role in RA pathogenesis, making JAK inhibitors an important therapeutic option. Tofacitinib, baricitinib, and upadacitinib are oral targeted synthetic disease-modifying antirheumatic drugs that interfere with … …OnLine Journal of Biological Sciences, Vol. 26, Issue 4 · 8 Oct 2026 · 430 accessesView PDFCite
Research ArticleOpen accessIn the abstractImpact of Vitamin D Deficiency on Cardio Metabolic Ageing in Middle Aged Adults in India: A Comparative AnalysisSumit Kumar, Adithi K, Shailaja S MoodithayaAdvancing age is accompanied by a gradual deterioration in physiological function, resulting in an increased risk of chronic diseases and early mortality. Growing evidence suggests that inadequate vitamin D status may be associated with unfavourable metabolic and cardiovascular alterations. Nevertheless, information regarding the association of vitamin D status with integrated cardio-metabolic biomarkers of ageing in middle-aged adults is currently limited. … …OnLine Journal of Biological Sciences, Vol. 26, Issue 3 · 3 Sep 2026 · 738 accessesView PDFCite
Research ArticleOpen accessIn the abstractEW-GAT: Edge-Weighted Graph Attention Framework for Patient-Aware Heart Disease Classification Using Feature-to-Feature Similarity GraphsRamakrishna Reddy Badveli, Nijaguna Gollara Siddappa, Sundeep Kumar KanipakapatnamHeart disease remains an important cause of global death, requiring accurate and clinically interpretable prediction models. However, traditional Machine Learning (ML) methods often fail to capture meaningful dependencies among clinical features and lack robustness across diverse patient populations. To overcome these issues, this research introduces an Edge-Weighted Graph Attention Network (EW-GAT) for patient-aware heart disease classification. The approach first models … …Journal of Computer Science, Vol. 22, Issue 7 · 25 Jul 2026 · 920 accessesView PDFCite