Sign inSubmit
Tips: “quotes” for a phrase · author:Lee · a DOI goes straight to its article

37 results for “Alexander N. Orekhov”
Set a search alert
Review ArticleOpen accessIn the author namesFemale Sex Hormones Contribute to Vulnerability to Athero-Sclerosis: Overview of Mechanisms and Specific Risk FactorsAnastasia Vladimirovna Poznyak, Victoria Alexandrovna Khotina, Alexandra Alexandrovna Melnichenko et al.Atherosclerosis poses a significant challenge to the general population, with its prevalence particularly prominent among older individuals. Age, however, is not the sole determinant of risk, as gender also plays a crucial role. Sex-related disparities exist not only in the incidence of atherosclerosis but also in its progression and development. The intricate interplay of hormones in the female reproductive system … …OnLine Journal of Biological Sciences, Vol. 24, Issue 2 · 11 Jan 2024 · 4,635 accessesView PDFCite
Review ArticleOpen accessIn the author namesOverview of the Most Popular Currently Used Murine Models of AtherosclerosisAnastasia Vladimirovna Poznyak, Victoria Alexandrovna Khotina, Alexandra Alexandrovna Melnichenko et al.Atherosclerosis is a widespread and serious problem. Every year it causes a huge number of deaths and morbidity. Many aspects of this disease remain not fully understood, which indicates the need to search for the most representative model of atherosclerosis in animal and cell culture models. Animal models resembling the pathophysiology in humans are needed to study the immunometabolic mechanisms … …OnLine Journal of Biological Sciences, Vol. 24, Issue 2 · 4 Jan 2024 · 4,673 accessesView PDFCite
Literature ReviewOpen accessIn the author namesMitochondrial Dysfunction Model in the Pathogenesis of Inflammatory Response Development in ObesityAlexander Blagov, Varvara Orekhova et al.Obesity is one of the growing problems of modern society. Although currently used methods of treating obesity, including diet, exercise, and drug therapy, have shown their applicability to more effectively combat obesity, an understanding of the pathogenesis of this disease is required. One of the insufficiently studied factors in the pathogenesis of obesity is the development of mitochondrial dysfunction understanding … …OnLine Journal of Biological Sciences, Vol. 24, Issue 1 · 19 Nov 2023 · 4,937 accessesView PDFCite
Research ArticleOpen accessIn the author namesThe Association of Blood Serum Atherogenicity with Risk Factors for Cardiovascular DiseaseTatiana Vladimirovna Kirichenko, Igor Alexandrovich Sobenin et al.Cardiovascular Diseases (CVD) caused by atherosclerosis are the most frequent cause of mortality worldwide, so the identification of new biomarkers of atherosclerosis development is quite actual. The atherogenicity of blood serum is considered as the potential of human serum to cause cholesterol accumulation in primary culture macrophages. The current study aimed to evaluate the association of the atherogenicity of blood … …OnLine Journal of Biological Sciences, Vol. 24, Issue 1 · 30 Oct 2023 · 4,921 accessesView PDFCite
Review ArticleOpen accessIn the author namesCardiolipin in Pathology: Implications in AtherosclerosisAnastasia Vladimirovna Poznyak, Vasily Nikolaevich Sukhorukov, Anton Yuvenalievich Postnov et al.Mitochondria are cell organelles whose main role is to generate the energy needed for cell biochemical reactions via oxidative phosphorylation. Cardiolipin is a phospholipid that is present in the inner mitochondrial membrane and other energy-transducing membranes. Mitochondrial structure largely depends on cardiolipin, as it is involved in the biogenesis of mitochondrial cristae, folds in the inner mitochondrial membrane designed to … …OnLine Journal of Biological Sciences, Vol. 23, Issue 4 · 23 Sep 2023 · 4,794 accessesView PDFCite
Review ArticleOpen accessIn the author namesBrief Overview of Specific Features of Cancer in Atherosclerosis Patients and Therapeutic StrategiesAnastasia Vladimirovna Poznyak, Varvara Alexandrovna Orekhova, Vasily Nikolaevich Sukhorukov et al.Cardiovascular Conditions (CVD) as well as cancer are the main death causes globally. Characteristically, there are numerous interrelations and intersections between these two groups of diseases. So, in particular, cardiovascular disease is one of the main comorbidities and death causes in cancer patients. The development of atherosclerosis is promoted by aggressive anticancer therapy regimens and various risk factors, including hypertension, … …OnLine Journal of Biological Sciences, Vol. 23, Issue 4 · 22 Sep 2023 · 4,526 accessesView PDFCite
Review ArticleOpen accessIn the author namesSubfractions of Low-Density-Lipoprotein: Which is the Most Atherogenic?Anastasia Vladimirovna Poznyak, Vasily Nikolaevich Sukhorukov, Mikhail Аleksandrovich Popov et al.Atherosclerosis is a widespread disease of the arteries, which manifests itself in the narrowing of the lumen of the vessel due to the formation of plaque on its walls. Despite an impressive history of study, atherosclerosis still leaves room for researchers. This is realized due to the complexity of pathogenesis, in which important roles are assigned to a variety of … …OnLine Journal of Biological Sciences, Vol. 23, Issue 4 · 3 Sep 2023 · 4,706 accessesView PDFCite