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325 results for “Objective Model”

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Research ArticleOpen accessAll words, across the recordConstrained Probabilistic Lost Sales Inventory System with Normal Distribution and Varying Order CostHala, A. Fergany, Mona, F. EL-WakeelThis study derives the probabilistic lost sales inventory system when the order cost is a function of the order quantity. Our objective is to minimize the expected annual total cost under a restriction on the expected annual holding cost when the lead-time demand follows the normal distribution by using the Lagrangian method. Then a published special case is deduced and … …Journal of Mathematics and Statistics, Vol. 2, Issue 1 · 31 Mar 2006 · 7,195 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordModeling Hepatocellular Toxicity of Enavatuzumab, a Humanized Anti-TweakR AntibodyDonghee Choi, Yanhong Zhu, Debra Tien Chao et al.In a Phase 1 clinical study, treatment with enavatuzumab, a humanized monoclonal antibody to TweakR, resulted in liver toxicity in a subset of patients. The objective of this current study was to evaluate the ability of preclinical studies to predict liver toxicity in humans. Enavatuzumab was evaluated in cynomolgus monkeys, where serum liver enzyme and cytokine levels were measured and … …American Journal of Pharmacology and Toxicology, Vol. 12, Issue 2 · 9 Nov 2017 · 7,719 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordField Scale Modeling to Estimate Phosphorus and Sediment Load Reductions Using a Newly Developed Graphical User Interface for Soil and Water Assessment ToolAaron R. Mittelstet, Erin R. Daly, Daniel E. Storm et al.Streams throughout the North Canadian River watershed in northwest Oklahoma, USA have elevated levels of nutrients and sediment. Soil and Water Assessment Tool (SWAT) was used to identify areas that likely contributed disproportionate amounts of Phosphorus (P) and sediment to Lake Overholser, the receiving reservoir at the watershed outlet. These sites were then targeted by the Oklahoma Conservation Commission (OCC) … …American Journal of Environmental Sciences, Vol. 8, Issue 6 · 28 Dec 2012 · 6,470 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordPerformance Analysis and Components Irreversiblities of a (25 MW) Gas Turbine Power Plant Modeled with a Spray CoolerFidelis Ibiang Abam, Ikpi U. Ugot, Dodeye Ina IgbongIn this study the effect of inlet air cooling system and components irreversibilities on the performance of an active 25MW gas turbine power plant was investigated. The objective of this study was to establish the potential benefits of improving the performance of the current gas turbine plant into a more advanced cycle with high efficiency and power output through inlet … …American Journal of Engineering and Applied Sciences, Vol. 5, Issue 1 · 24 Feb 2012 · 9,379 accessesView PDFCite
Research ArticleOpen accessAll words, across the recordEvaluation of a Dual-Purpose Chemical Applicator for Paddy FieldsMohammed Shu’aibu Abubakar, Desa Ahmad, Othman Jamarei et al.Problem statement: One of the major problems of rice production is the shortage of labor resulting from migration from rural to urban areas, making it very difficult to meet peak demands for paddy production. In most developing countries of Southeast Asia, agricultural mechanization of paddy field operation is mostly carried out using conventional machines. For example in rice production powerintensive … …American Journal of Applied Sciences, Vol. 8, Issue 4 · 18 Apr 2011 · 7,542 accessesView PDFCite