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302 articles for “Rats”
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Research ArticleOpen accessIn the abstractGrowth of Bone Marrow Derived Osteoblast-Like Cells into Coral Implant Scaffold: Preliminary Study on Malaysian CoralK. A. AL-SalihiProblem statement: Biomaterial fabrication in Malaysia started as a consequence of the demand for cheaper implant materials. Various biomaterials have been developed utilizing local resources like Malaysian coral. Locally processed Malaysian coral need to be complemented with proper evaluation and testing including toxicology, biocompatibility, mechanical properties, physicochemical characterization and in vivo testing. The present study was carried out to assess … …American Journal of Biochemistry and Biotechnology, Vol. 5, Issue 3 · 30 Sep 2009 · 6,590 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnti-Inflammatory Activity of Vitex leucoxylon L. Bark Extracts Against Freund's Complete Adjuvant Induced Arthritis in Sprague Dawley RatAlluri V. Krishnaraju, Chundi B.M. Rao, Dodda Sundararaju et al.Problem statement: Anti-inflammatory agents, particularly steroids and cyclooxygenase inhibitors are often associated with adverse side effects including, GI irritation, ulcers, hypertension and cardiac abnormalities. A safe and effective intervention is essential for the treatment of inflammatory disorders. Approach: Abstract Vitex leucoxylon L., a medicinal plant of the verbenaceae family, used in traditional medicine for relieving headache and catarrh. VL-89/185A, was … …American Journal of Infectious Diseases, Vol. 5, Issue 2 · 30 Jun 2009 · 8,044 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Hypoglycemic Properties of BAE Maca Max PreparationEdward V. Krizhanovsky, Kamila B. Tursunova, Lim Kwong Choong, Ng Chee PingProblem statement: Considering an urgency of a question of diabetes treatment and decrease the side effects of hypoglycemic therapies, there is a necessity to elaborate a new approaches to this problem. This study was directed on estimation of possibilities of a preparation of naturally modified BAE maca max product for improvement of semeiology of diabetes and reduce the glucose level … …OnLine Journal of Biological Sciences, Vol. 9, Issue 1 · 31 Mar 2009 · 7,848 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Bacillus subtilis 'PB6' (ATCC - PTA 6737) on Clostridium difficile Associated Diarrhea (CDAD) and Inflammatory Bowel Disease (IBD) in Animal ModelsEric Peys, Jerry Varghese, Ponusami Suresh et al.The administration of probiotic bacteria is emerging as a potential means of preventing the onset or recurrence of Clostridium difficile associated diarrhea (CDAD) and of attenuating inflammatory activity and preventing relapses in inflammatory bowel disease (IBD). We evaluated the efficacy of Bacillus subtilis 'PB6' (ATCC - PTA 6737) in a hamster model of antibiotic-induced CDAD and in a rat model … …American Journal of Infectious Diseases, Vol. 3, Issue 4 · 31 Dec 2007 · 7,097 accessesView PDFCite
Research ArticleOpen accessIn the abstractEvaluation of the Immunomodulatory Properties of a Calf Lipid Thymus Extract and Standardization of a Method for Quantification of its Biological ActivityMiodrag Colic, Radmila Popovic, Dusanka Mrdakovic et al.The aim of this study was to test the immunobiological properties of a new formulation of the lipid thymus calf extract (Thymsol), prepared for in vitro cell culture experiments. At first, we showed that Thymsol enhanced the antigen specific immune response in AO rats in vitro, using Keyhole limpet hemocyanin (KLH). At lower concentrations (0.5-2.5 μg mL-1) the extract increased … …American Journal of Immunology, Vol. 3, Issue 2 · 31 Dec 2007 · 7,039 accessesView PDFCite
Research ArticleOpen accessIn the abstractChromium Picolinate did not Effect on the Proliferation and Differentiation of MyoblastsM.C. Tsa, T.F. LienThis experiment is conducted in vitro to investigate trivalent chromium picolinate affects the proliferation and differentiation of myoblasts. A myoblasts cell line (C2C12) from rats was used in the experiment. These were randomly divided into the control group, the Pic group (50ppb picolinate) and the CrPic group (50ppb chromium picolinate). The differentiation of myoblasts reveals that the number of differentiated … …American Journal of Animal and Veterinary Sciences, Vol. 2, Issue 4 · 31 Dec 2007 · 6,414 accessesView PDFCite
Research ArticleOpen accessIn the abstractCorrelation Between MMP-3, TIMP-3 Expression and Neuronal Apoptosis After Ischemia -Reperfusion Injury in RatesZi Xiaohong, Mutasem Abuhamed, Yuan Yi et al.Matrix metalloproteinases (MMPs) play a central role in many biological processes, such as embryogenesis, normal tissue remodeling, wound healing, and angiogenesis. How MMP3, TIMP3 expression and neuronal apoptosis (Fas, Fas-L and Bcl) may provide detrimental or beneficial actions during the injury and repair processes after cerebral ischemia-reperfusion injury in rates was studied. Adult rats underwent middle cerebral artery occlusion (MCAO) … …American Journal of Immunology, Vol. 3, Issue 2 · 30 Nov 2007 · 7,175 accessesView PDFCite
Research ArticleOpen accessIn the abstractCardiovascular Effect of Capparis spinosa Aqueous Extract. Part VI: in vitro Vasorelaxant EffectN. A. Zeggwagh, J. B. Michel, M. EddouksThe aim of this study was to investigate the in vitro vasorelaxanteffect of Capparis spinosa aqueous extract (CSAE) at a dose of 10 mg mL-1. Aortic rings isolated from normal wistar rats were used. The addition of CSAE during the plateau phase of contraction, induced by noradrenaline and KCl, produced a rapid relaxation. Incubation of aortic ring with CSAE during … …American Journal of Pharmacology and Toxicology, Vol. 2, Issue 3 · 30 Sep 2007 · 7,444 accessesView PDFCite
Research ArticleOpen accessIn the abstractIntranasal Administration of Quercetin Liposome Decreases Anxiety-like Behavior and Increases Spatial MemoryJintanaporn Wattanathorn, Wathita Phachonpai, Aroonsri Priprem, Saengrawee SuthiparinyanontAt present, the effects of quercetin liposome on anxiolytic activity and cognitive function are unclearly known. In this study, male Wistar rats were administered quercetin liposome via intranasal route once daily continually for 4 weeks. The anxiolytic activity and cognitive enhancing effect were determined after single administration, 1, 2, 3 and 4 weeks of treatment using elevated plus maze test … …American Journal of Agricultural and Biological Sciences, Vol. 2, Issue 1 · 31 Mar 2007 · 9,091 accessesView PDFCite
Research ArticleOpen accessIn the abstractInflammatory Cytokine Expression Patterns in Rat Skin Exposed to JP-8 Jet FuelRandle M. Gallucci, Bethany M. MickleOne of the main complaints of personnel exposed to JP-8 jet fuel is irritant dermatitis. The purpose of this investigation is to describe the JP-8 induced inflammatory cytokine response in skin over various periods of exposure. JP-8 jet fuel or acetone control (300 μL) was applied to the denuded skin of rats once a day for up to seven days. … …American Journal of Pharmacology and Toxicology, Vol. 1, Issue 3 · 30 Sep 2006 · 7,042 accessesView PDFCite