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82 articles for “underlying mechanism”
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Literature ReviewOpen accessIn the abstractAtherosclerosis and Alzheimer’s Disease Interconnection: Inflammation, Aβ and MoreAnastasia Vladimirovna Poznyak, Victoria Khotina, Roghayyeh Vakili-Ghartavol et al.Despite being the leading cause of CVD and cardiovascular mortality globally, Atherosclerosis (ATH) remains underdiagnosed and undertreated. The reasons behind Alzheimer’s Disease (AD) also remain unclear and there is currently no cure for it. At present, at least 55 million people are believed to be suffering from the disorder and the figures are expected to grow. At the same time, … …OnLine Journal of Biological Sciences, Vol. 24, Issue 4 · 26 May 2024 · 4,764 accessesView PDFCite
Review ArticleOpen accessIn the abstractLong Way of Evaluating Niacin for Atherosclerosis TreatmentAnastasia Vladimirovna Poznyak, Victoria Alexandrovna Khotina, Elizaveta Mikhailovna Pleshko et al.Atherosclerosis is a significant public health challenge, as it is closely associated with a wide range of cardiovascular diseases and complications. Despite its grave implications, the timely detection and treatment of atherosclerosis remain complex tasks due to the intricate pathogenesis involved, which encompasses numerous processes and mechanisms. Extensive research has been conducted to investigate various therapeutic methods and drugs aimed … …OnLine Journal of Biological Sciences, Vol. 24, Issue 3 · 24 Feb 2024 · 5,123 accessesView PDFCite
Review ArticleOpen accessIn the abstractFemale Sex Hormones Contribute to Vulnerability to Athero-Sclerosis: Overview of Mechanisms and Specific Risk FactorsAnastasia Vladimirovna Poznyak, Victoria Alexandrovna Khotina, Alexandra Alexandrovna Melnichenko et al.Atherosclerosis poses a significant challenge to the general population, with its prevalence particularly prominent among older individuals. Age, however, is not the sole determinant of risk, as gender also plays a crucial role. Sex-related disparities exist not only in the incidence of atherosclerosis but also in its progression and development. The intricate interplay of hormones in the female reproductive system … …OnLine Journal of Biological Sciences, Vol. 24, Issue 2 · 11 Jan 2024 · 4,635 accessesView PDFCite
EditorialOpen accessIn the abstractBig Data and Parkinson’s Disease - from Understanding of Disease to Personalised MedicineYen F. Tai, Nicola PaveseThe advancement of information technology in recent years has generated a huge amount of datasets in all areas of scientific research. This has led to new opportunities to harness the 'Big Data' to improve our understanding of diseases - from investigating disease mechanisms to monitoring treatment responses. The Big Data approach is a data-driven and often hypothesis-free, way of studying … …Neuroscience International, Vol. 7, Issue 1 · 27 Jul 2016 · 7,761 accessesView PDFCite
Literature ReviewOpen accessIn the abstractThe Effects of Glucocorticoids on Trabecular Meshwork and its Role in GlaucomaAlina GenisPrimary Open-Angle Glaucoma (POAG), an optic neuropathy that is a leading cause of irreversible blindness, has been studied extensively in hopes of better understanding its underlying mechanism. Glucocorticoids (GC) are commonly used to treat inflammatory ocular conditions but are also known to increase the risk of glaucoma by raising Intraocular Pressure (IOP) in susceptible individuals, leading to steroid-induced glaucoma. Based … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 4 · 14 Oct 2015 · 8,224 accessesView PDFCite
Research ArticleOpen accessIn the abstractBispectral Analysis of Scalp Electroencephalograms: Quadratic Phasecoupling Phenomenon in Detecting Brain TumorV. Salai Selvam, S. ShenbagadeviSince the power spectral analysis of a non-Gaussian process generated by a nonlinear mechanism e.g., EEG, does not provide much information on the underlying nonlinear dynamics due to the lack of phase information, the higher-order statistics such as the bispectra are used to better understand the underlying nonlinear dynamics e.g., the quadratic phase coupling phenomena. The quadratic phase couplings have … …American Journal of Applied Sciences, Vol. 10, Issue 3 · 27 Mar 2013 · 6,542 accessesView PDFCite
Research ArticleOpen accessIn the abstractMulberry Fruits Extract Mitigate Vascular DementiaPratchaya Kaewkaen, Jintanaporn Wattanathorn, Terdthai Thong-Un et al.To date, Vascular Dementia (VaD) is the second most commonly found dementia following Alzheimer�s disease. Though VaD is still increasing its importance, the therapeutic efficacy is still not in satisfaction level. Therefore, the searching for an acceptable cheap and safe neuroprotective agent is in a great demand. Based on the neuroprotective and cognitive enhancing effects in alcohol neurotoxicity of mulberry … …American Journal of Applied Sciences, Vol. 9, Issue 11 · 1 Sep 2012 · 6,973 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffects of Mulberry Fruit Powder in Animal Model of StrokePratchaya Kaewkaen, Terdthai Tong-Un, Jintanaporn Wattanathorn et al.Stroke is the leading cause of death and the important cause of disability worldwide. Presently, the effectiveness of therapeutic strategy is still very limited. Based on the role neuroprotective effect of substance possessing antioxidant effect previously reported, we hypothesized mulberry fruit a substance possessing anti-oxidant activity, might be able to protect against cognitive impairment induced by stroke or cerebral ischemia. … …American Journal of Agricultural and Biological Sciences, Vol. 7, Issue 3 · 15 Aug 2012 · 9,042 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Stringent Authorization using Principles and Policy for Grid ComputingA. R. Jayasudha, T. PurusothamanProblem statement: The current information security mechanisms are insufficient to address authorization issues. The access control models today are mostly static and they are not wellsuited for the service-oriented environments where information access is dynamic in nature. Traditional authorization security techniques do not directly address these concerns as they primarily use access control lists for authorization, where the user whose … …Journal of Computer Science, Vol. 7, Issue 8 · 8 Aug 2011 · 6,638 accessesView PDFCite
Research ArticleOpen accessIn the abstractRole of Evaporation in Degrading the "Oil Lakes"Al Rashed Ahamad, Colin BarkerProblem statement: Oil Spills are degraded by aerobic bacteria, water washing, evaporation and oxidation. In the absence of water the first two of these processes cannot operate. This is the situation in the low rainfall environment of the Kuwaiti desert where oil lakes still persist 20 years after the initial spills. The oils contain longer chain n-alkanes but have lost … …American Journal of Environmental Sciences, Vol. 7, Issue 3 · 11 Jul 2011 · 6,750 accessesView PDFCite