Research ArticleOpen accessIn the abstractEmerging Trends in Designing Short and Efficient Protein Purification ProtocolsSaurabh Gautam, Joyeeta Mukherjee, Ipsita Roy, Munishwar Nath GuptaProtein purification is carried out in both academic and industrial sectors. Both non-chromatographic approaches (precipitation, crystallization, partitioning) and chromatographic methods are used. When recombinant proteins are over expressed in foreign hosts, inclusion bodies are obtained. Many purification methods can be used to refold proteins. Many strategies allow one to avoid formation of inclusion bodies. The concept of affinity based separation … …American Journal of Biochemistry and Biotechnology, Vol. 8, Issue 4 · 25 Dec 2012 · 9,007 accessesView PDFCite
Research ArticleOpen accessIn the abstractThe Wear of Tunnel Boring Machine Excavation Tools in RockClaudio Oggeri, Pierpaolo OresteSome of the most important aspects in the study of the fragmentation of rock due to the action of TBM disks concern the abrasiveness of the rock and the wear of the tools. The wear of the disks in fact means that they have to be substituted, with consequent effects on the efficiency of the excavation, on the speed of … …American Journal of Applied Sciences, Vol. 9, Issue 10 · 16 Aug 2012 · 7,654 accessesView PDFCite
Research ArticleOpen accessIn the abstractVariability of Hydraulic Conductivity Due to Multiple FactorsSanjit K. Deb, Manoj K. ShuklaSoil properties are greatly influenced by intrinsic factors of soil formation as well as extrinsic factors associated with land use and management and vary both in time and space. Intrinsic variability is caused by the pedogenesis and usually takes place at large time scales. The variability caused by extrinsic factors could take effect relatively quickly and could not be treated … …American Journal of Environmental Sciences, Vol. 8, Issue 5 · 13 Aug 2012 · 10,219 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Wireless Sensor Node Supporting Various Powers Supply and Communication MethodsStefan Gruber, Hannes Reinisch, Hartwig Unterassinger et al.Problem statement: This study presents a wireless sensor node dedicated for in-tire pressure and temperature monitoring. Additional features set it apart from the many different systems available on the highly competitive market. State-of-the-art implementations are mounted on the rim of a tire. Here the sensor node will be mounted on the inner liner of the tire. By moving the sensor … …American Journal of Engineering and Applied Sciences, Vol. 4, Issue 4 · 12 Jan 2012 · 8,032 accessesView PDFCite
Research ArticleOpen accessIn the abstractModeling Heterogeneity in Phase II Clinical TrialsChristopher N. Barnes, Shesh N. RaiProblem statement: The common assumption in non-randomized Phase II clinical trials is a homogeneous population with homogeneous response. This assumption is at odds with many trials today; a heterogeneous response due to the existence of subgroups. Approach: In order to examine the effects of heterogeneity on the trial outcome, a systematic platform is developed to quantify the range and classes … …Current Research in Biostatistics, Vol. 1, Issue 1 · 30 Jun 2010 · 10,127 accessesView PDFCite
Research ArticleOpen accessIn the abstractLand Cover Change Detection Using Texture AnalysisXiaofeng Wu, Fen Yang, Roly LishmanProblem statement: It is an important task to detect land cover changes from remotely sensed data for environmental monitoring. Although there are some applications of visual textures to the land use, they are limited to a few land cover categories with the application of one texture measure. Since land cover types are complex and often the integration of various objects, … …Journal of Computer Science, Vol. 6, Issue 1 · 31 Jan 2010 · 8,198 accessesView PDFCite
Research ArticleOpen accessIn the abstractA Note on Model Selection in Mixture ExperimentsKadri Ulaş AkayIn mixture experiments, determination of the best model for modeling the mixture system is significant in both understanding and interpreting the system. For obtaining the best model in mixture experiments, different methods have been used. Most commonly used methods are the stepwise type methods. However, the models obtained with these methods are not always the best model depending on the … …Journal of Mathematics and Statistics, Vol. 3, Issue 3 · 30 Sep 2007 · 6,939 accessesView PDFCite
Research ArticleOpen accessIn the abstractImproved SVM with Hyperparameter Tuning for Fake News DetectionAtcharaporn Nachaithong, Kittipol WisaengIn today’s digital age, accessing information has become effortless. An abundance of resources is available online, from trustworthy news outlets providing factual information to unverified opinions shared by anonymous individuals. With the advent of modern technology, social media platforms have revolutionized interaction and staying informed, providing instant access to news and information related to a wide range of topics. They … …Journal of Computer Science, Vol. 20, Issue 10 · 28 Aug 2024 · 5,636 accessesView PDFCite
Review ArticleOpen accessIn the abstractUnveiling the Impact of Endogenous Sialidases on Human Non-Infectious Disease PathogenesisRaisa Sergeevna Surkova, Anastasia Vladimirovna Poznyak, Dmitry Alexandrovich Kashirskikh et al.In our review, we have compiled existing information regarding the role of endogenous sialidases (neuraminidases) in the initiation and development of various non-infectious processes in humans. Precisely, pathologies of the cardiovascular system, tumor formations, neurological and metabolic disorders, and hereditary diseases. Sialidases appeared to be widely involved in a variety of human pathologies. An increase or decrease in the enzymatic … …OnLine Journal of Biological Sciences, Vol. 24, Issue 3 · 10 Feb 2024 · 4,546 accessesView PDFCite