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82 articles for “plasma concentration”
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Research ArticleOpen accessIn the abstractAnalytical Method Validation of Vilazodone with Spectrofluorimetric Detection in Rabbit PlasmaIrene Sartini, Marco Salvadori, Beata Łebkowska-Wieruszewska et al.Vilazodone (VLZ) is an antidepressant agent approved in 2011 by Food and Drug Administration (FDA) for the treatment of major depressive syndromes. Its chemical structure derives from trazodone which is used as an off-label drug for dogs and cats in order to induce sedation and reduce anxiety, behavioural and pre-and post-operative stress. VLZ could be a potentially useful compound in … …American Journal of Animal and Veterinary Sciences, Vol. 14, Issue 1 · 2 Apr 2019 · 7,744 accessesView PDFCite
Research ArticleOpen accessIn the abstractStudies on Pharmacokinetics and Liver Microsome Metabolism of Nuciferine in Different Species of AnimalsDong Xiao-Chen, Liu Ming-Qi, Liu Jun et al.This study aimed to compare the characteristics of pharmacokinetics and liver microsome metabolism among different species of animals including rabbit, rat and mouse and healthy New Zealand white rabbits, SPF Sprague Dawley (SD) rats and ICR mice were given intraperitoneal injection of nuciferine at a dose of 50 mg per kg body weight. Blood samples were collected via caudal vein … …American Journal of Biochemistry and Biotechnology, Vol. 17, Issue 3 · 12 Aug 2021 · 6,473 accessesView PDFCite
Research ArticleOpen accessIn the abstractInfrared Thermography and Metabolic Changes in Castrated Piglets due to the Effects of Age and the Number of Incisions in the TesticlesEfraín Pérez-Pedraza, Daniel Mota-Rojas, Miguel González-Lozano et al.The objective of the study was to evaluate infrared temperature and metabolic responses in different-aged piglets castrated surgically with one or two incisions. The piglets were divided into groups according to age (5- and 13-day old) and the number of incisions: simulated castration; castration with one incision (C1I5 and C1I13); and castration via two incisions (C2I5 and C2I13). Temperature evaluations … …American Journal of Animal and Veterinary Sciences, Vol. 13, Issue 3 · 4 Oct 2018 · 8,180 accessesView PDFCite
Research ArticleOpen accessIn the abstractNovel LC-MS/MS Method for CJ-023423 (Grapiprant) Determination in Rabbit PlasmaElena Baralla, Virginia De Vito, Maria Vittoria Varoni et al.Grapiprant is a new anti-inflammatory drug that preferentially targets the EP4 receptor of prostaglandin E2 limiting the wide range of adverse effects caused by the classical non steroideal anti-inflammatory drugs. The aim of this study was to develop and validate a new, simple, sensitive and rapid Liquid Chromatography tandem Mass Spectrometry method (LC-MS/MS) in order to quantify this novel drug … …American Journal of Animal and Veterinary Sciences, Vol. 13, Issue 2 · 24 May 2018 · 7,995 accessesView PDFCite
Research ArticleOpen accessIn the abstractEffect of Platelet Rich Plasma on Post Cryopreservation Viability, Morphology and Proliferation of Human Umbilical Cord Stem CellsNoviyanti Goei, Isabella Kurnia Liem, Jeanne Adiwinata Pawitan, Dian MedianaIn most cryopreservation medium, Fetal Bovine Serum (FBS) is used as supplement, while it is well known that FBS contains xenoproteins that can be incorporated into the cells and may be harmfull, as they can elicit immune response. Therefore, finding other xenofree materials as FBS alternative in cryopreservation medium is very important. Platelet Rich Plasma (PRP) is albumin rich and … …OnLine Journal of Biological Sciences, Vol. 15, Issue 2 · 4 Jun 2015 · 7,390 accessesView PDFCite
Research ArticleOpen accessIn the abstractDETERMINATION THE CONCENTRATION OF SOME METALS IN IMPORTED CANNED FOOD AND CHICKEN STOCKM. A. AL-RajhiThis study was carried out to determine the level of same selected metals namely Cd, Cr, Cu, Fe, K, Mg, Mn, Ni, Pb, Zn, As, Se, Al and V in some imported canned foods and chicken stock purchased from the local market in Riyadh, Saudi Arabia. The measurements were performed using inductively coupled plasma-optical emission Spectrometer (SPECTRO) analytical instruments. The … …American Journal of Environmental Sciences, Vol. 10, Issue 3 · 5 May 2014 · 7,456 accessesView PDFCite
Research ArticleOpen accessIn the abstractSTUDY OF SOME HEAVY METALS AND TRACE ELEMENTSAL-Rajhi, M.A.This study provides an overview of the measurements of trace elements and heavy metals in table salt in Saudi Arabia. The aim of this study is to investigate the heavy metal concentration in different type of salt samples consumed in Riyadh Saudi Arabia and comparing the concentrations of such elements with the limits recommended by the World Health Organization (WHO) … …Physics International, Vol. 5, Issue 2 · 22 Apr 2014 · 7,109 accessesView PDFCite
Research ArticleOpen accessIn the abstractBONE MEAL AS ALTERNATIVE TREATMENT FOR ACIDIC AND METAL CONTAMINATED ACID MINE DRAINAGE WATER EFFLUENT: LAB SCALECarolyn Payus, Olga David, Moh Pak YanThe typical methods of treatment for acidic and metal contaminated water effluent such as the Acid Mine Drainage (AMD) will always focus on either civil engineering methods, such as disposal, excavation, drainage and encapsulation or process based technologies such as effluent washing and treatment. These techniques are not environmental friendly, costly and unsustainable, thus environmental damaging. Nowadays, there is a … …American Journal of Environmental Sciences, Vol. 10, Issue 1 · 3 Mar 2014 · 7,981 accessesView PDFCite
Research ArticleOpen accessIn the abstractChemical and Statistical Analyses of Elements in River Water of Morava e BincesFatbardh Gashi, Naser Troni, Fatmir Faiku et al.The objective of this research was assessment of environmental toxic elements downstream the river of Morava e Binces (Kosovo) and this study is a continuation of earlier studies of surface waters in our country. The sampling and analysis are conducted in accordance with EU and WHO standards. This study uses both quantitative and qualitative analysis to assess the water quality … …American Journal of Environmental Sciences, Vol. 9, Issue 2 · 8 Apr 2013 · 8,679 accessesView PDFCite
Research ArticleOpen accessIn the abstractButyrate-Mediated Genomic Changes Involved in Non-Specific Host Defenses, Matrix Remodeling and the Immune Response in the Rumen Epithelium of Cows Afflicted with Subacute Ruminal AcidosisLouis Dionissopoulos, Anne Hermen Laarman, Ousama AlZahal et al.Subacute Ruminal Acidosis (SARA) is a disorder in cattle which can lead to chronic inflammation in the rumen epithelium, known as rumenitis. Butyrate has been shown to attenuate some of the detrimental effects of inflammatory gastroenteral disorders but the molecular mechanisms mediated by butyrate have not been defined. The objective of this study was to define the inflammatory-related genomic changes … …American Journal of Animal and Veterinary Sciences, Vol. 8, Issue 1 · 10 Jan 2013 · 8,065 accessesView PDFCite