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38 articles for “inhibitory compounds”
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Research ArticleOpen accessIn the abstractExtraction, Partial Identification and Bioactivities of Total Flavonoids from Carex meyeriana KunthHongbiao Wang, Penghui Wang, Xiudong Yang et al.To date, knowledge associated with extraction, chemical constituents and bioactivities of Total Flavonoids from Carex meyeriana Kunth (TFCMK) that remains unclear. Therefore, this paper was designed to optimize the ethanol reflux extraction method by response surface methodology and determine the chemical constituents by Liquid Phase-Mass Spectrometry (HPLC-MS); additionally, the bioactivities including antioxidant, antibacterial and hemolysis test were also explored. The … …American Journal of Biochemistry and Biotechnology, Vol. 15, Issue 3 · 7 Aug 2019 · 7,523 accessesView PDFCite
Research ArticleOpen accessIn the abstractMicrowave Assisted Regioselective Synthesis and Biological Evaluation of Pyrano[2,3-c]Pyridine Derivatives Utilizing DMAP as a CatalystAsmaa M. FahimRegioselective facile production of pyrano[2,3-c]pyridine through multicomponent reaction of aromatic aldehydes, ethyl cyano acetate or malononitrile and C-H activated compound of 3-hydroxy picolinic acid in the occurrence of smaller amount of DMAP catalyst utilizing microwave apparatus, which is green and simple environmentally with high yield, recyclability catalyst. Totally the products were partitioned for antimicrobiogical action; it was detected that were … …OnLine Journal of Biological Sciences, Vol. 17, Issue 4 · 14 Dec 2017 · 8,019 accessesView PDFCite
Research ArticleOpen accessIn the abstractBioactive Compounds from Sponge Associated Bacteria: Anticancer Activity and NRPS-PKS Gene Expression in Different Carbon SourcesJepri Agung Priyanto, Rika Indri Astuti, Jun Nomura, Aris Tri WahyudiSponge associated bacteria with diverse NRPS-PKS genes could be the alternative source of bioactive compounds. This study aimed to analyze the activity as well as the regulatory mechanism regarding the anticancer properties derived from these bacteria against cancer cell lines. Extraction of bacterial metabolites using ethyl acetate solvent resulted yield ranging from 0.003 to 0.016% (w/v). Six extracts of bacterial … …American Journal of Biochemistry and Biotechnology, Vol. 13, Issue 4 · 5 Oct 2017 · 8,886 accessesView PDFCite
Research ArticleOpen accessIn the abstractAntibacterial Activity of Lotus Leaves (Nelumbo Nucifera) Against Food-Borne PathogensJianxin Chen, Changyin Wang, Xiaotian Chen et al.The antibacterial activity of different solvent extracts from lotus leaves against four food-borne bacteria (Escherichiacoli, Salmonellatyphimurium, Staphyloccocusaureus, Bacillussubtilis) was analyzed by agar diffusion method and the ethanol extract of the plant was found to have the highest antimicrobial activity with the diameter of inhibition zones ranging from 17.2 to 17.8 mm. Then the ethanol extract of lotus leaves were further … …American Journal of Biochemistry and Biotechnology, Vol. 11, Issue 1 · 18 Nov 2014 · 10,152 accessesView PDFCite
Research ArticleOpen accessIn the abstractINHIBITORY ACTIVITY OF POTENTOX AGAINST DNA GYRASE OF ENTEROBACTERIACEAEManu Chaudhary, Anurag PayasiDNA gyrase, a type II topoisomerase catalyzes the supercoiling of relaxed closed circular DNA. In this report we evaluated the in vitro inhibitory effect of non antibiotic adjuvant compounds disodium edetate and sodium citrate against supercoiling activity of bacterial DNA gyrase. Further, we assessed the effect of different drugs alone and in combination with one or more adjuvants in overcoming … …American Journal of Infectious Diseases, Vol. 10, Issue 1 · 8 Feb 2014 · 7,288 accessesView PDFCite
Research ArticleOpen accessIn the abstractCHEMICAL ANALYSIS AND ANTIOXIDANT ACTIVITY OF "NERIUM OLEANDER" LEAVESLakhmili Siham, Obraim Saida, Taourirte Moha et al.The phenolic products of medicinal plants have a great pharmacological interest. This product gives the powers of medicinal plants. They are the source of several active principles widely used in modern medicine. The use of Nerium oleander in Moroccan traditional medicine is very common. Few studies have focused on the chemical analysis and phenolic compounds of this plant. For this, … …OnLine Journal of Biological Sciences, Vol. 14, Issue 1 · 13 Dec 2013 · 8,285 accessesView PDFCite
Research ArticleOpen accessIn the abstractCOMPARATIVE STUDY OF IN VITRO ANTIMICROBIAL ACTIVITIES OF FOENICULUM VULGARE MILL. (UMBELLIFERAE) EXTRACTKhadija Dahak, Moha TaourirteThe importance to push scientifically the investigations on the organic extracts of the plants aromatic as potential source of new antimicrobial compounds comes from the traditional use of the plants. However, the consumption of these natural products requires à thorough research in this field. The antimicrobial effect of organic and aqueous leaves extracts of Foeniculum vulgare Mill., However, which makes … …OnLine Journal of Biological Sciences, Vol. 13, Issue 4 · 12 Oct 2013 · 8,671 accessesView PDFCite
Research ArticleOpen accessIn the abstractPhytochemical and Pharmacological Evaluation of Selected PlantsSneh Verma, Tandra Mohanta, T. Revathy et al.Araucaria cookii, Bauhinia blakeana and Brassaia actinophylla are ornamental plants. The presence of various phytochemicals and pharmacologically important compounds in these plants can be exploited for their medicinal use. But there are no reports on the phytochemical and pharmacological evaluation of these plants and this study aims at investigating these. The plant extracts were prepared in different solvents like methanol, … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 3 · 21 Sep 2013 · 8,217 accessesView PDFCite
Research ArticleOpen accessIn the abstractAnti-Oxidant and Enzyme-Inhibitory Potential of Marine StreptomycesT. Revathy, M. A. Jayasri, K. SuthindhiranMarine actinomycetes are potential source for the discovery of novel compounds and enzymes. Though extensive research on marine actinomycetes is underway globally, the actinomycetes research from Indian marine ecosystem is unexplored and understudied. Hence, the present research is focussed on the screening of bioactive compounds from marine actinomycetes isolated from Indian coastal region. This study is designed to determine the … …American Journal of Biochemistry and Biotechnology, Vol. 9, Issue 3 · 21 Sep 2013 · 7,239 accessesView PDFCite
Research ArticleOpen accessIn the abstractBio-Guided Study on Melastoma malabathricum Linn Leaves and Elucidation of its Biological ActivitiesMourouge Saadi Alwash, Nazlina Ibrahim, Wan Yaacob AhmadThe present study aimed to isolate and identify constituents with antibacterial activity from the Methanol extract of Melastoma malabathricum leaves (MMML) through bioassay guided fractionation. Furthermore, the study scoped to evaluate the cytotoxic effects of M. malabathricum leaves fractions for possible protective effect of antoxidative constituents present in the fractions. The MMML extract was fractionated by Vacuum Liquid Chromatography (VLC) … …American Journal of Applied Sciences, Vol. 10, Issue 8 · 24 Jul 2013 · 9,513 accessesView PDFCite